Chlorthalidone | 77-36-1

Cas No :

77-36-1

Form :

Solid

Molecular Weight :

338.77 G/Mol

Molecular Formula :

C14H11CLN2O4S

Boiling Point :

600 °C

Melting Point :

270 °C

Flash Point :

190 °C

Solubility :

Sparingly Soluble In Water; Soluble In Acetone And Methanol

Description :

Overview of Chlorthalidone

Chlorthalidone is a thiazide-like diuretic pharmaceutical active ingredient widely used in the management of hypertension and fluid retention (oedema). It works by increasing the excretion of sodium and water through the kidneys, thereby reducing blood volume and lowering blood pressure.

Chlorthalidone appears as a white to off-white crystalline powder with good chemical stability. It is practically insoluble in water but soluble in organic solvents, making it suitable for solid oral dosage forms such as tablets. Due to its long duration of action and proven clinical efficacy, Chlorthalidone is commonly used in long-term cardiovascular therapy.

ChemicalBull supplies pharma-grade Chlorthalidone with high purity, consistent particle size, and reliable batch-to-batch quality suitable for regulated pharmaceutical manufacturing. Each shipment is supported with complete documentation, including MSDS, COA, and technical data sheets, ensuring compliance with pharmaceutical quality standards.

As a trusted chemical supplier and reliable distributor, ChemicalBull ensures dependable availability of Chlorthalidone. You may also like Hydrochlorothiazide, Indapamide, Metolazone, and Pharmaceutical APIs for related antihypertensive and diuretic applications.

Applications of Chlorthalidone

Pharmaceutical Formulations

  • Used in antihypertensive tablet formulations

  • Applied in oedema and fluid management therapies

  • Suitable for long-term cardiovascular treatment

Cardiology & Clinical Use

  • Used in the treatment of high blood pressure

  • Applied in heart failure and fluid retention management

  • Widely prescribed in cardiovascular care

Generic Drug Manufacturing

  • Used in branded and generic diuretic medicines

  • Suitable for large-scale pharmaceutical production

  • Ensures consistent potency and formulation stability

Pharmaceutical Research & Development

  • Used in bioequivalence and formulation studies

  • Applied in cardiovascular drug research

  • Suitable for controlled pharmaceutical laboratories

Safety & Handling Guidelines

  • Handle using gloves and appropriate protective equipment

  • Avoid inhalation of fine powder

  • Use in well-ventilated pharmaceutical manufacturing areas

  • Store in tightly sealed containers protected from moisture

  • Follow MSDS and standard pharmaceutical safety practices

Where to Buy Chlorthalidone?

Chlorthalidone Manufacturer

ChemicalBull supplies pharmaceutical-grade Chlorthalidone suitable for antihypertensive and diuretic drug formulations.

Chlorthalidone Supplier & Distributor

  • Bulk and customised pharmaceutical packaging options

  • Export-grade quality with COA, TDS & MSDS

  • Reliable supply across India and international markets

  • Trusted chemical supplier for pharmaceutical APIs

Chlorthalidone MSDS

The Chlorthalidone MSDS provides essential information on safe handling, storage conditions, exposure controls, stability, and emergency procedures. Always review the MSDS before bulk handling or pharmaceutical manufacturing use.

Frequently Asked Questions (FAQs)

  1. Why is Chlorthalidone considered long-acting?

    It has a longer half-life compared to many other diuretics, allowing sustained blood pressure control.

  2. Is Chlorthalidone chemically the same as thiazide diuretics?

    No, it is thiazide-like but has a different chemical structure.

  3. Can Chlorthalidone be used in combination therapies?

    Yes, it is often combined with other antihypertensive agents.

  4. Is Chlorthalidone water-soluble?

    No, it is practically insoluble in water.

  5. Is safety documentation provided with the supply?

    Yes, every shipment includes MSDS, COA, and complete technical documentation.