N,N-Diisopropylcarbodiimide | 693-13-0

Description :

Overview of N,N-Diisopropylcarbodiimide

N,N-Diisopropylcarbodiimide (DIC) is a widely used coupling reagent in organic synthesis, particularly in peptide synthesis and pharmaceutical intermediate manufacturing. It is primarily employed for activating carboxylic acids to facilitate amide bond formation, making it essential in API development and fine chemical production.

N,N-Diisopropylcarbodiimide appears as a clear to pale yellow liquid with good reactivity and stability under controlled conditions. It is soluble in most organic solvents and is valued for its efficiency in carbodiimide-mediated coupling reactions. Due to its selective reactivity and reduced by-product formation compared to some other carbodiimides, it is extensively used in laboratory and industrial-scale synthesis.

ChemicalBull supplies pharma and industrial-grade N,N-Diisopropylcarbodiimide with controlled purity, consistent reactivity, and reliable batch-to-batch performance. Each shipment is supported with complete documentation, including MSDS, COA, and technical data sheets.

As a trusted chemical supplier and reliable distributor, ChemicalBull ensures dependable availability of N,N-Diisopropylcarbodiimide. You may also like DCC (Dicyclohexylcarbodiimide), EDC Hydrochloride, HATU, and Pharmaceutical Intermediates for related peptide coupling and synthesis applications.

Applications of N,N-Diisopropylcarbodiimide

Pharmaceutical Intermediates

• Used in peptide bond formation

• Applied in API and drug intermediate synthesis

• Supports amide coupling reactions
  
  

Peptide & Organic Synthesis

• Used in solid-phase and solution-phase peptide synthesis

• Applied in the activation of carboxylic acids

• Enables efficient condensation reactions
  
  

Research & Development

• Used in medicinal chemistry research

• Applied in laboratory-scale reaction optimisation

• Suitable for pilot and industrial-scale production
  
  

Fine Chemical Manufacturing

• Used in speciality organic compound synthesis

• Applied in custom contract manufacturing

• Ensures controlled and reproducible reaction outcomes
  
  

Safety & Handling Guidelines

• Handle using gloves and appropriate protective equipment

• Avoid inhalation of vapours and skin contact

• Use in well-ventilated laboratories or processing areas

• Store in tightly sealed containers away from moisture

• Follow MSDS and standard chemical safety practices
  
  

Where to Buy N,N-Diisopropylcarbodiimide?

N,N-Diisopropylcarbodiimide Manufacturer

ChemicalBull supplies pharma and industrial-grade N,N-Diisopropylcarbodiimide suitable for peptide synthesis and pharmaceutical intermediate production.

N,N-Diisopropylcarbodiimide Supplier & Distributor

• Bulk and customised packaging options

• Export-grade quality with COA, TDS & MSDS

• Reliable supply across India and international markets

• Trusted chemical supplier for pharmaceutical intermediates and coupling reagents
  
  

N,N-Diisopropylcarbodiimide MSDS

The N,N-Diisopropylcarbodiimide MSDS provides essential information on safe handling, storage conditions, exposure controls, chemical stability, and emergency procedures. Always review the MSDS before handling or industrial use.

Frequently Asked Questions (FAQs)

1. Why is N,N-Diisopropylcarbodiimide commonly used in peptide synthesis?

   It efficiently activates carboxylic acids for amide bond formation.
   
   

2. How does DIC differ from DCC?

   DIC forms more easily removable urea by-products compared to DCC.
   
   

3. Is N,N-Diisopropylcarbodiimide supplied as a liquid?

   Yes, it is typically available as a clear to pale yellow liquid.
   
   

4. Can N,N-Diisopropylcarbodiimide be used in industrial-scale manufacturing?

   Yes, it is widely used in both laboratory and large-scale pharmaceutical production.
   
   

5. Is safety documentation provided with the supply?

   Yes, every shipment includes MSDS, COA, and complete technical documentation.