L-Proline | 147-85-3

Cas No :

147-85-3

Synonyms :

Form :

Powder

Molecular Weight :

115.13 G/Mol

Molecular Formula :

C5H9NO2

Boiling Point :

250 °C

Melting Point :

187 °C

Flash Point :

210 °C

Solubility :

Soluble In Water; Soluble In Ethanol

Description :

Overview of L-Proline

L-Proline (C5H9NO2) is a unique proteinogenic amino acid characterized by its secondary amine structure, where the side chain cyclizes back onto the nitrogen atom to form a five-membered pyrrolidine ring. Naturally occurring and essential for human physiology, it is a white crystalline powder primarily recognized as the fundamental building block of collagen. As a prominent speciality chemicals manufacturer, Chemical Bull offers high-purity L-Proline, refined to meet the stringent demands of the pharmaceutical, nutraceutical, and technical sectors.

Crystalline powder is primarily recognized as the fundamental building block of collagen. As a prominent speciality chemicals manufacturer, Chemical Bull offers high-purity L-Proline, refined to meet the stringent demands of the pharmaceutical, nutraceutical, and technical sectors.

Whether you are seeking an L-Proline manufacturer for the synthesis of ACE inhibitors or for formulating high-performance skincare and joint-support products, our material ensures a consistent purity profile and excellent solubility. To explore how our grades can optimize your specific chemical process, you can connect with our technical team directly to discuss bulk supply and current market pricing.

 

Applications of L-Proline

As an established industrial chemical manufacturer in India, we supply L-Proline to several specialized manufacturing streams:

  • Pharmaceuticals: A vital starting material for the synthesis of ACE inhibitors (such as Captopril and Enalapril) used in blood pressure management. As a pharma-grade chemical manufacturer, we provide materials with high optical purity and low impurity profiles.

  • Cosmeceuticals & Personal Care: Essential for anti-aging formulations. As the primary precursor to collagen, it is used in topical creams and serums to improve skin elasticity and promote tissue repair.

  • Nutraceuticals: Widely used in the production of sports nutrition and joint-health supplements. It supports the maintenance of cartilage and connective tissues.

  • Asymmetric Organocatalysis: Utilized as a "green" chiral catalyst in organic synthesis. It is highly valued by speciality chemical manufacturers for its ability to drive enantioselective reactions like the Aldol condensation.

  • Agro Chemicals Manufacturers: Acts as a powerful osmoprotectant. It is formulated into biostimulants to help crops withstand environmental stresses like drought, salinity, and extreme temperatures.

  • Cell Culture Media: A necessary component in many fermentation processes and biotechnological applications to support robust cell growth and protein expression.

 

Safety, MSDS & Professional Storage

Due to its hygroscopic nature and crystalline form, professional handling is a top priority:

  • MSDS Profile: Registered under CAS No. 147-85-3. It is generally recognized as non-hazardous for transport; however, standard precautions should be taken to avoid inhalation of dust.

  • Handling: Wear appropriate PPE, including safety goggles and gloves. Use a dust mask during bulk handling to avoid respiratory irritation.

  • Storage: Store in a cool, dry, and dark warehouse. Because L-Proline is hygroscopic, it must be kept in original, tightly sealed packaging to prevent clumping and degradation. Keep away from strong oxidizing agents.

  • Regulatory Compliance: Every shipment is accompanied by a full COA and MSDS, ensuring it meets the rigorous quality standards for pharmaceutical and food-grade distribution.


Where to Buy?

L-Proline Manufacturer

Chemical Bull is a leading partner with a high-purity chemical manufacturer in India and a key chemical manufacturer in Gujarat. We ensure our L-Proline maintains a high assay ($98.5\%$ min) with strictly controlled specific rotation and residue levels. As a trusted chemical manufacturer in India, we provide consistent quality across every batch to ensure your production remains uninterrupted.


L-Proline Suppliers & Distributors

Operating from the industrial hub of Vapi, we manage a specialized supply chain for bulk distribution across domestic and international markets. We provide logistics for standard 25kg bags and fiber drums, ensuring the material is protected from moisture due to its hygroscopic nature. Our chemical manufacturers' contact desk ensures that all technical documentation, including COA and stability data, is provided for your regulatory compliance.


Related Products

  • L-Hydroxyproline – A derivative essential for collagen stability and specialized pharma synthesis.

  • L-Arginine – Often used in conjunction with Proline in cardiovascular and sports nutrition formulations.

  • Glycine – Another primary amino acid found in high concentrations within collagen structures.

  • L-Lysine – Frequently paired with Proline for tissue repair and immune system support

 

L-Proline MSDS


L-Proline is a stable amino acid generally recognized as safe; however, in concentrated form, it is hygroscopic and may cause mild respiratory or eye irritation. It should be stored in a cool, dry, well-ventilated warehouse in tightly sealed, moisture-proof packaging to maintain stability. For a detailed COA or technical dossier, please submit your bulk inquiry to our sales division for current lead times.

Frequently Asked Questions (FAQ)

  1. What is the primary role of L-Proline in skincare?

    L-Proline is essential for collagen synthesis. By promoting collagen production, it enhances skin elasticity and helps maintain structural firmness, making it a common active ingredient in anti-aging products.

  2. Is L-Proline safe for use in food and supplements?

    Yes, L-Proline is a naturally occurring amino acid and is widely regarded as safe for use in nutritional supplements, functional foods, and beverages.

  3. How does L-Proline differ from other amino acids?

    L-Proline is unique because it is a cyclic amino acid (a secondary amine). This structure gives it structural rigidity, which is critical for the stability of proteins like collagen.