Atovaquone | 95233-18-4
Cas No :
95233-18-4
Form :
Powder
Molecular Weight :
345.40 G/Mol
Molecular Formula :
C22H19CLO3
Boiling Point :
450 °C
Melting Point :
172 °C
Flash Point :
280 °C
Solubility :
Practically Insoluble In Water; Soluble In Organic Solvents (E.g., Dmso, Methanol, Ethanol)
Description :
Overview of Atovaquone
Atovaquone is a pharmaceutical-grade antiprotozoal active pharmaceutical ingredient (API) used primarily in the treatment and prevention of certain parasitic infections. It belongs to the hydroxynaphthoquinone class of compounds and is known for its activity against malaria parasites and Pneumocystis jirovecii.
In pharmaceutical manufacturing, Atovaquone is valued for its targeted antimicrobial activity and suitability for oral dosage forms such as tablets and suspensions. It is produced under controlled GMP conditions to ensure purity, consistent potency, and regulatory compliance.
As a pharma chemical, Atovaquone is mainly used in anti-malarial and antiparasitic product development.
Applications of Atovaquone
Antimalarial Formulation Development
Atovaquone is widely used in combination therapies for the prevention and treatment of malaria. It is commonly formulated with Proguanil Hydrochloride to enhance therapeutic effectiveness and reduce resistance development.
Treatment of Opportunistic Infections
Atovaquone is used in formulations intended for the treatment and prevention of Pneumocystis pneumonia (PCP), particularly in immunocompromised patients. It may be evaluated alongside Trimethoprim and Sulfamethoxazole in infection-management portfolios.
Regulated Pharmaceutical Manufacturing Use
Atovaquone is manufactured under strict pharmaceutical standards to ensure high purity and batch consistency. The API is suitable for large-scale GMP-compliant production for global pharmaceutical markets.
Safety & Handling Guidelines
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Store in a cool and dry place
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Protect from moisture and direct light
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Keep containers tightly sealed
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Avoid inhalation of dust during handling
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Avoid direct contact with eyes and skin
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Use appropriate personal protective equipment
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Follow pharmaceutical manufacturing safety standards
Where to Buy Atovaquone?
Atovaquone Manufacturer
Atovaquone is manufactured for pharmaceutical applications requiring controlled potency, consistent quality, and regulatory documentation.
Atovaquone Supplier & Distributor
Pharmaceutical-grade Atovaquone is supplied in suitable packaging for formulation companies. As a pharmaceutical chemicals supplier and distributor, Chemicalbull Pvt. Ltd. supports reliable sourcing with standard documentation.
MSDS for Atovaquone
The MSDS for Atovaquone provides detailed information regarding safe handling, storage requirements, exposure controls, and emergency procedures. It should be reviewed prior to pharmaceutical manufacturing use.
Frequently Asked Questions (FAQs)
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What is Atovaquone?
Atovaquone is an antiprotozoal pharmaceutical ingredient used to treat and prevent malaria and certain opportunistic infections such as Pneumocystis pneumonia. -
What is Atovaquone used for?
Atovaquone is used for the prevention and treatment of malaria and for managing Pneumocystis pneumonia, particularly in patients with weakened immune systems. -
What are the side effects of Atovaquone?
Common side effects of Atovaquone may include nausea, vomiting, diarrhea, headache, rash, and abdominal discomfort. Medical supervision is recommended during treatment. -
Which is better, Doxycycline or Atovaquone?
Doxycycline and Atovaquone are used for different clinical purposes. Doxycycline is a broad-spectrum antibiotic often used for malaria prevention and bacterial infections, while Atovaquone is specifically used in antimalarial and antiparasitic treatments. The choice depends on the medical condition and physician recommendation. -
What is another name for Atovaquone?
Atovaquone is commonly known by brand names in finished formulations, such as in combination products containing Atovaquone and Proguanil. The generic name remains Atovaquone.