Sodium Ethoxide | 141-52-6

Cas No :

141-52-6

Synonyms :

Form :

Solid

Molecular Weight :

68.05 G/Mol

Molecular Formula :

C2H5NAO

Boiling Point :

200 °C

Melting Point :

157 °C

Flash Point :

12 °C

Solubility :

Soluble In Ethanol; Reacts With Water To Form Ethanol And Sodium Hydroxide

Description :

Overview of Sodium Ethoxide 

Sodium Ethoxide, also known as Sodium Ethylolate, is a potent alkoxide and a strong nucleophilic base with a Molecular Weight of 68.05 g/mol and a Melting Point of 260°C (Decomposes). Sodium Ethoxide Chemical Formula(structure) is C2H5NaO. As a premier Industrial Chemical Supplier, Chemical Bull manufactures and distributes Sodium Ethoxide in both a free-flowing 98% powder and a 21% ethanol solution.

Identified by CAS 141-52-6, this compound is significantly more basic than sodium hydroxide. It is a cornerstone reagent in anhydrous organic chemistry, favored for its ability to facilitate complex carbon-carbon bond formations without the interference of water.

Application of Sodium Ethoxide 

The Sodium Ethoxide manufacturing process at Chemical Bull involves the controlled reaction of high-purity sodium metal with anhydrous ethanol under a strict nitrogen blanket. This prevents the formation of sodium hydroxide and ensures the active content remains stable.


Pharmaceutical Synthesis 

In the Pharmaceutical Intermediates, it is a "Star" reagent:

  • Condensation Reactions: It is the primary catalyst for Claisen Condensations, used to synthesize esters, vitamins (such as Vitamin B1), and various barbiturates.

  • Ring Closure: Facilitates the formation of heterocyclic rings essential for many Active Pharmaceutical Ingredients (APIs).   

  • Synergistic Synthesis: It is frequently used alongside reagents like triphosgene in advanced organic synthesis to build complex molecular frameworks for modern medicine.

 

Biodiesel Manufacture

Sodium Ethoxide is the preferred industrial use catalyst in high-efficiency energy plants:

  • Transesterification: It converts triglycerides into biodiesel more effectively than traditional hydroxides. Because it does not produce water as a byproduct, it prevents "soaping" and maximizes fuel yield. During final processing, organic acids like Lactic Acid may be used for precise pH neutralization.


Fine Chemical & Organic Synthesis

  • Ether Synthesis: A key nucleophile in Williamson Ether Synthesis for the production of high-end fragrances and dyes.

  • Solvent Compatibility: Often formulated with anhydrous solvents like Ethyl Lactate to ensure reaction stability in moisture-sensitive environments


Safety, Handling & Professional Storage

Due to its high reactivity and corrosive nature, safe handling is mandatory:

  • Handling: Sodium Ethoxide is highly alkaline and moisture-sensitive. It reacts with atmospheric humidity to form Sodium Hydroxide and Ethanol. Always use specialized PPE, including nitrile gloves and a full-face shield, to prevent chemical burns.

  • Storage: Store in a cool, dry, and nitrogen-purged environment. To maintain chemical integrity, containers must be hermetically sealed. This prevents the product from absorbing CO_2 and degrading into sodium carbonate.

  • Regulatory Compliance: Every batch is rigorously tested for "Free Alkali" and "Active Content," backed by a comprehensive COA and MSDS.


Why Buy from Chemical Bull?

Sodium Ethoxide Manufacturer 

  • Assay Stability: We guarantee high-purity levels by using vacuum-sealed, moisture-barrier packaging that protects the product's reactive potency.

  • Bulk Versatility: We support manufacturing requirements ranging from small-scale R&D to metric-ton industrial production.

  • Technical Support: Our team provides the exact solubility and purity profiles required to satisfy your internal Quality Assurance (QA) and safety protocols.


Sodium Ethoxide Supplier & Distributor

we cater to both small-scale R&D labs and large-scale industrial plants. We provide flexible packaging options, ranging from vacuum-sealed moisture-barrier bags for 98% powder to specialized steel drums for 21% liquid solutions, ensuring safe transit to any industrial hub.


MSDS 
Sodium Ethoxide 

Due to its corrosive and moisture-sensitive nature, safe handling is our priority. Every batch is supplied with an updated MSDS (Material Safety Data Sheet) and a COA (Certificate of Analysis). These documents provide critical data on flammability, pH, and emergency neutralisation procedures to ensure your facility meets international safety standards.


Frequently Asked Questions (FAQs)

  1. Why is the 260°C Melting Point significant?
    While it shows the solid's thermal limits, the product decomposes at this temperature. For manufacturing safety, reactions using Sodium Ethoxide are typically performed at much lower temperatures.

  2. What is the shelf life of the 98% powder?
    In original, nitrogen-blanketed packaging, it remains stable for 12 months. Exposure to air will cause rapid degradation through moisture absorption.

  3. Can Sodium Ethoxide be used in water-based reactions?
    Absolutely not. It reacts immediately and violently with water. All Sodium Ethoxide uses must be conducted in anhydrous (water-free) organic solvents.