Diclofenac Diethylamine | 78213-16-8

Cas No :

78213-16-8

Form :

Solid

Molecular Weight :

369 G/Mol

Molecular Formula :

C18H22CL2N2O2

Boiling Point :

310 °C

Melting Point :

170 °C

Flash Point :

210 °C

Solubility :

Soluble In Water; Soluble In Ethanol; Sparingly Soluble In Nonpolar Solvents

Description :

Overview of Diclofenac Diethylamine

Diclofenac Diethylamine is a pharmaceutical-grade salt of diclofenac, developed to enhance solubility and skin penetration in topical and transdermal formulations. It belongs to the non-steroidal anti-inflammatory drug (NSAID) category and is widely used in pain and inflammation management products.

In pharmaceutical manufacturing, Diclofenac Diethylamine is valued for its improved bioavailability in topical applications, consistent anti-inflammatory activity, and formulation flexibility. Diclofenac Diethylamine API Manufacturer in India supplies this compound under GMP conditions to meet pharmacopeial and regulatory requirements.

As a pharma chemical, Diclofenac Diethylamine is primarily used in topical gels, sprays, and dermatological preparations.


Applications of Diclofenac Diethylamine

Pharmaceutical API & Topical Formulations

Diclofenac Diethylamine is extensively used as an active pharmaceutical ingredient in topical and transdermal formulations designed for localised pain relief and inflammation control. Its diethylamine salt form supports enhanced skin absorption and rapid onset of action.

In topical NSAID formulation development, it is often evaluated alongside Diclofenac Sodium for route-of-administration selection.

Pharmaceutical Chemistry & Functional Characteristics

From a pharmaceutical chemistry perspective, the diclofenac diethylamine structure consists of the diclofenac anion complexed with diethylamine, resulting in improved solubility and formulation compatibility. Diclofenac diethylamine's solubility characteristics make it suitable for semi-solid and liquid dosage forms.

Its molecular properties support consistent performance in topical pharmaceutical products.

Industrial & Regulated Manufacturing Use

Diclofenac Diethylamine is manufactured as a high-purity pharmaceutical raw material with strict control over assay, residual solvents, and impurity profile. It is suitable for large-scale pharmaceutical production under regulated environments.

In pain-management API research, it may be referenced alongside compounds such as Ketoprofen and Ibuprofen for comparative anti-inflammatory formulation studies.


Safety & Handling Guidelines

  • Store in a cool, dry, and controlled environment
  • Protect from light and moisture
  • Keep containers tightly sealed and clearly labelled
  • Avoid inhalation of dust during handling
  • Avoid direct contact with skin and eyes
  • Use appropriate personal protective equipment
  • Handle under controlled pharmaceutical manufacturing conditions
  • Dispose of waste according to regulatory guidelines


Where to Buy Diclofenac Diethylamine?

Diclofenac Diethylamine Manufacturer

Diclofenac Diethylamine is manufactured for pharmaceutical applications where controlled synthesis, consistent potency, and regulatory compliance are essential. Diclofenac Diethylamine API Manufacturer in India supplies regulated material for domestic and export markets.

Diclofenac Diethylamine Supplier & Distributor

Pharmaceutical-grade Diclofenac Diethylamine is supplied in suitable packaging for formulation manufacturers. As a pharmaceutical chemicals supplier and distributor, Chemicalbull Pvt. Ltd. supports reliable sourcing with standard documentation.


MSDS for Diclofenac Diethylamine

The MSDS for Diclofenac Diethylamine provides information on chemical hazards, handling precautions, storage conditions, exposure controls, and emergency measures. It should be reviewed before use in pharmaceutical manufacturing.


Frequently Asked Questions (FAQs)

  1. What is Diclofenac Diethylamine used for?

    Diclofenac Diethylamine is used in pharmaceutical formulations for localised pain and inflammation management, mainly in topical applications.

  2. What is the classification of Diclofenac Diethylamine?

    Diclofenac Diethylamine is classified as a non-steroidal anti-inflammatory drug (NSAID).

  3. What are the side effects of Diclofenac Diethylamine?

    Diclofenac diethylamine side effects may include local skin irritation when used topically, depending on formulation and exposure.

  4. What is the solubility of Diclofenac Diethylamine?

    Diclofenac diethylamine solubility is higher than that of other diclofenac salts, supporting its use in topical and semi-solid dosage forms.

  5. What is the structure of Diclofenac Diethylamine?

    Diclofenac diethylamine structure consists of diclofenac combined with diethylamine to enhance absorption and formulation stability.