Diacerein | 13739-02-1

Description :

Overview of Diacerein

Diacerein is a drug that slowly acts to treat disease-modifying osteoarthritis (DMOAD), which is used to treat osteoarthritis as well as degenerative joint diseases. It is renowned for its anti-inflammatory, anabolic and anti-catabolic effects for cartilage metabolism. Diacerein is frequently utilised in rheumatology to aid the long-term treatment of osteoarthritis.

This API appears as a yellow-to-orange crystalline powder and is stable under controlled storage conditions. Its mechanism—inhibition of interleukin-1β (IL-1β) synthesis and activity—reduces cartilage degradation, stimulates cartilage repair, and provides symptomatic relief in osteoarthritis.

Related products include Glucosamine, Chondroitin Sulfate, Ibuprofen, and other disease-modifying and symptomatic osteoarthritis treatments.

Applications of Diacerein

Pharmaceutical API

• Used in disease-modifying osteoarthritis medications
• Effective in treating knee, hip, and other joint osteoarthritis
• Reduces pain, stiffness, and improves joint function
• Slows the structural progression of osteoarthritis

Formulation Development

• Used in capsules and tablets
• Suitable for long-term therapy formulations
• Often combined with NSAIDs like Ibuprofen for a synergistic effect
• Offers good stability in solid dosage forms

Rheumatological Treatment

• Provides sustained symptomatic relief with continued use
• Modifies disease progression by protecting cartilage
• Reduces the need for NSAIDs and analgesics over time
• Suitable for patients who cannot tolerate NSAIDs

Safety & Handling Guidelines

• Avoid inhalation of fine powder
• Use gloves, goggles, and protective clothing during handling
• Store in a cool, dry place away from light and moisture
• Follow COA and MSDS instructions strictly

Where to Buy Diacerein?

Diacerein Manufacturer

ChemicalBull provides Diacerein with high-purity API that is in compliance with specifications for quality of IP/EP/USP in the pharmaceutical industry.

Diacerein Supplier & Distributor

• In bulk packaging for formula units
• High-purity and stable for use in research and production
• COA MSDS as well as regulatory documentation available

MSDS

Provides detailed safety guidelines, including hazard identification as well as storage guidance .

Frequently Asked Questions (FAQs)

1. What is the Diacerein dosage?
   

   Typical adult dosage is 50 mg twice daily, taken with meals. Treatment should be initiated gradually to minimise gastrointestinal side effects.
   
   

2. What is Diacerein injection?
   

   Diacerein is primarily available as an oral formulation (capsules/tablets). Injectable forms are not standard; the medication is designed for oral administration.
   
   

3. What are the uses of the Diacerein tablet?
   

   Diacerein tablets are used for long-term treatment of osteoarthritis, reducing joint pain and stiffness while slowing cartilage degradation.
   
   

4. What is Diacerein used for?
   

   It is used as a disease-modifying agent in the treatment of osteoarthritis, particularly of the knee and hip joints.
   
   

5. How does Diacerein work?
   

   Diacerein inhibits the production and activity of interleukin-1β, a key inflammatory cytokine involved in cartilage breakdown, thereby protecting cartilage and reducing inflammation.