1-Bromo-4-Iodobenzene | 589-87-7

Description :

Overview of 1-Bromo-4-Iodobenzene

1-Bromo-4-Iodobenzene is a halogenated aromatic compound widely used as an industrial intermediate in organic synthesis, pharmaceutical production, and advanced material chemistry. It has bromine and Iodine substituents, which are placed opposite to each other in a benzene ring. This makes it extremely valuable in the process of selective cross-coupling.

As an industrial chemical, 1-Bromo-4-Iodobenzene is primarily applied in palladium-catalysed coupling processes such as Suzuki, Heck, and Sonogashira reactions, where differentiated halogen reactivity enables stepwise functionalization.

Applications of 1-Bromo-4-Iodobenzene

Suzuki Coupling & Cross-Coupling Reactions

1-Bromo-4-Iodobenzene is extensively used in Suzuki coupling reactions due to the higher reactivity of the iodine substituent compared to bromine. This permits specific substitution, which makes it extremely effective in multi-step syntheses.

It may be processed alongside Tetrakis-Triphenylphosphine Palladium, 4-Fluorophenylboronic Acid, and Triphenylphosphine Oxide in structured cross-coupling systems.

Advanced Material & Electronic Chemicals

1-Bromo-4-Iodobenzene is used in the preparation of speciality polymers, OLED materials, and fine electronic intermediates.

Fine Chemical Production

It supports the production of substituted aromatic compounds in agrochemical and speciality chemical industries.

Safety & Handling Guidelines

• Store in tightly sealed containers in a cool, dry place
• Avoid exposure to heat and open flames
• Prevent inhalation of vapours
• Avoid skin and eye contact
• Use protective gloves and safety goggles
• Handle under proper industrial ventilation

Always consult the MSDS before industrial handling.

Where to Buy 1-Bromo-4-Iodobenzene?

1-Bromo-4-Iodobenzene Manufacturer

1-Bromo-4-Iodobenzene is manufactured under controlled industrial standards to ensure high purity and consistent halogen substitution performance.

1-Bromo-4-Iodobenzene Supplier & Distributor

Buy 1-Bromo-4-Iodobenzene from Chemicalbull Pvt. Ltd., a reputable industrial chemical distributor and supplier in India with dependable sources and an efficient logistics service.

For bulk supply and pricing details, contact Chemicalbull Pvt. Ltd. for a competitive industrial quotation.

MSDS for 1-Bromo-4-Iodobenzene

The MSDS for 1-Bromo-4-Iodobenzene provides detailed information on hazard identification, safe handling procedures, storage requirements, exposure controls, and emergency response measures.

Frequently Asked Questions (FAQs)

1. What is the formula of 1-Bromo-4-Iodobenzene?
   

   The chemical formula of 1-Bromo-4-Iodobenzene is C6H4BrI.
   
   

2. What is the structure of 1-Bromo-4-Iodobenzene?
   

   It is composed of a benzene ring that has been substituted by a bromine atom as well as an iodine atom located in the para (1,4-) position.
   
   

3. How is 1-Bromo-4-Iodobenzene used in Suzuki coupling?
   

   In Suzuki coupling, the iodine group typically reacts first due to higher reactivity, allowing selective carbon–carbon bond formation.
   
   

4. Is 1-Bromo-4-Iodobenzene soluble in organic solvents?
   

   Yes, it is soluble in common organic solvents such as toluene, dichloromethane, and ethanol, but insoluble in water.
   
   

5. How is 1-Bromo-4-Iodobenzene synthesized?
   

   It is typically synthesised via controlled chemical reactions such as halogenation or substitution under controlled industrial conditions.