Overview of Diisopropyl Azodicarboxylate
Diisopropyl Azodicarboxylate (DIAD) is an organic azo compound widely used as a reagent in organic synthesis, particularly in the Mitsunobu reaction. It typically appears as a yellow to orange liquid and is valued for its ability to facilitate the conversion of alcohols into various functional groups through nucleophilic substitution reactions.
The compound is commonly referred to as Diisopropyl azodicarboxylate (DIAD) and has the molecular formula C₈H₁₄N₂O₄. The Diisopropyl Azodicarboxylate density is approximately 1.03 g/cm³ at 25°C. Due to its reactive azo functionality, it is mainly used in pharmaceutical synthesis, research laboratories, and specialty chemical production.
Applications of Diisopropyl Azodicarboxylate
Organic Synthesis & Mitsunobu Reactions
Diisopropyl Azodicarboxylate is widely used as a reagent in Mitsunobu reactions to convert alcohols into esters, ethers, or other functional derivatives. It plays an important role in forming carbon–oxygen and carbon–nitrogen bonds during organic transformations.
It is often used in combination with Triphenylphosphine in controlled reaction systems.
Pharmaceutical & API Intermediate Production
In pharmaceutical chemistry, DIAD is applied in the synthesis of drug intermediates and complex organic molecules where selective substitution reactions are required.
Research & Laboratory Applications
Diisopropyl Azodicarboxylate is commonly used in academic and industrial research laboratories for studying reaction mechanisms and developing new synthetic methodologies.
Diisopropyl Azodicarboxylate Synthesis
Diisopropyl azodicarboxylate synthesis is typically carried out through controlled oxidation of diisopropyl hydrazodicarboxylate using suitable oxidizing agents under regulated reaction conditions.
Safety & Handling Guidelines
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Store in tightly sealed containers in a cool, well-ventilated area
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Keep away from heat, sparks, and open flames
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Avoid inhalation of vapors and direct skin contact
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Use protective gloves, goggles, and laboratory protective clothing
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Handle under proper ventilation or a chemical fume hood
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Dispose of material according to hazardous waste regulations
Where to Buy Diisopropyl Azodicarboxylate?
Diisopropyl Azodicarboxylate Manufacturer
Diisopropyl Azodicarboxylate is manufactured under controlled chemical synthesis conditions to ensure high purity and stable performance for research and industrial applications.
Diisopropyl Azodicarboxylate Supplier & Distributor
Buy Diisopropyl Azodicarboxylate from Chemicalbull Pvt. Ltd., a trusted industrial chemical supplier and distributor in India offering reliable bulk supply and compliant logistics support.
For the latest Diisopropyl azodicarboxylate price and bulk supply details, contact Chemicalbull Pvt. Ltd. for a competitive industrial quotation.
MSDS for Diisopropyl Azodicarboxylate
The MSDS for Diisopropyl Azodicarboxylate provides detailed information on hazard identification, toxicity data, safe handling procedures, storage requirements, exposure controls, and emergency response measures. Industrial users must review the safety data sheet before use.
Frequently Asked Questions (FAQs)
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What is Diisopropyl Azodicarboxylate (DIAD)?
It is an azo compound used as a reagent in organic synthesis, especially in Mitsunobu reactions.
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What is Diisopropyl azodicarboxylate density?
The density is approximately 1.03 g/cm³ at 25°C.
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What are the hazards of diisopropyl azodicarboxylate?
It may cause irritation to skin, eyes, and respiratory system and should be handled with appropriate safety precautions.
