Triphenylphosphine Oxide | 791-28-6

Cas No :

791-28-6

Form :

Crystalline Solid

Molecular Weight :

278.3G/Mol

Molecular Formula :

C18H15OP

Melting Point :

150 - 157 °C

Boiling Point :

360 °C

Solubility :

Slightly Soluble In Water; Soluble In Methanol

Flash Point :

180 °C

Description :

Overview of Triphenylphosphine Oxide

Triphenylphosphine Oxide (TPPO) is an organophosphorus compound widely used as a chemical intermediate and stabiliser in organic synthesis and speciality chemical applications. It is the oxidised form of triphenylphosphine, possessing a phosphorus-oxygen double bond that gives it high stability and reactivity in various chemical processes.

TPPO is primarily employed in pharmaceutical synthesis, organophosphorus chemistry, and as a by-product in reactions like the Wittig reaction. It is strictly an industrial and laboratory chemical, not intended for food, fragrance, or cosmetic use.


Application of Triphenylphosphine Oxide

Pharmaceutical & Organic Synthesis Applications

Triphenylphosphine Oxide is used as a by-product or intermediate in Wittig, Mitsunobu, and other organophosphorus reactions.
It can also serve as a crystallisation aid, ligand, or stabiliser in multi-step organic synthesis.
Can be interlinked with related products such as Triphenylphosphine, Phosphine Derivatives, and Organophosphorus Reagents from the ChemicalBull.


Stabiliser & Catalysis Applications

Used as a stabiliser in polymer synthesis and organometallic chemistry.
Serves as a ligand or additive in catalysis, enhancing selectivity and reaction efficiency.
Commonly paired with other phosphorus-based reagents in research and industrial applications.


Research & Fine Chemical Applications

Widely used in academic and industrial research laboratories.
Valuable for studying phosphorus chemistry, reaction mechanisms, and organophosphorus ligand effects.
Used as a reference compound in organophosphorus reaction studies.

 

Safety and Handling Guidelines

  • Handle using gloves, safety goggles, and protective clothing

  • Avoid inhalation of dust and direct skin contact

  • Store in a cool, dry, and well-ventilated area

  • Keep containers tightly closed when not in use

  • Not intended for food, cosmetic, or fragrance applications

  • Follow MSDS and standard industrial safety protocols

Where to Buy Triphenylphosphine Oxide?

Triphenylphosphine Oxide Manufacturer

Produced by speciality chemical manufacturers under controlled conditions to ensure purity and consistency.


Triphenylphosphine Oxide Supplier & Distributor

ChemicalBull Pvt. Ltd. supplies Triphenylphosphine Oxide for pharmaceutical, organophosphorus, and specialty chemical applications.


MSDS for Triphenylphosphine Oxide

The MSDS contains information on safe handling, storage, and hazard management and is available on request.

 

Frequently Asked Questions (FAQs)

  1. What is Triphenylphosphine Oxide used for?

    It is used as a chemical intermediate, stabiliser, and ligand in pharmaceutical, polymer, and organophosphorus reactions.

  2. Is Triphenylphosphine Oxide safe for food or cosmetics?

    No, it is strictly an industrial and laboratory chemical.

  3. How is Triphenylphosphine Oxide formed?

    It is typically produced as the oxidation product of Triphenylphosphine in organic reactions such as the Wittig reaction.

  4. Can it be used in catalysis?

    Yes, it can act as a stabiliser or ligand in various catalytic processes.

  5. Which related products can be interlinked with Triphenylphosphine Oxide?

    Triphenylphosphine, Phosphine Derivatives, Organophosphorus Reagents, Phosphine Oxide Derivatives, and Speciality Chemical Intermediates.