Triphenylphosphine Oxide | 791-28-6
Cas No :
791-28-6
Form :
Crystalline Solid
Molecular Weight :
278.3G/Mol
Molecular Formula :
C18H15OP
Boiling Point :
360 °C
Flash Point :
180 °C
Solubility :
Slightly Soluble In Water; Soluble In Methanol
Description :
Overview of Triphenylphosphine Oxide
Triphenylphosphine Oxide is an organic phosphorus chemical that is extensively utilized as a chemical intermediate in industrial processes, as a catalyst by-product, and a ligand modification in organic syntheses. It is usually obtained in the form of a white crystal and typically occurs during reactions that involve triphenylphosphine.
As an industrial chemical, Triphenylphosphine Oxide plays an important role in pharmaceutical manufacturing, fine chemical synthesis, polymer chemistry, and coordination chemistry processes. It is valued for its thermal stability, coordination properties, and compatibility in advanced synthetic systems.
Applications of Triphenylphosphine Oxide
Pharmaceutical & Fine Chemical Intermediate
Triphenylphosphine Oxide is widely used in pharmaceutical and specialty chemical synthesis. It appears as a reaction intermediate or by-product in Wittig, Mitsunobu, and other phosphine-mediated transformations.
It may be processed alongside Triphenylphosphine, Tetrakis-Triphenylphosphine Palladium, and Bromobenzene in structured industrial synthesis systems.
Catalyst & Ligand Systems
Due to its phosphorus-oxygen functionality, Triphenylphosphine Oxide is used in coordination chemistry and metal complex stabilization. It acts as a ligand in certain catalytic and extraction processes.
It supports regulated industrial reaction systems.
Polymer & Resin Manufacturing
Triphenylphosphine Oxide is utilized in specialty resin and polymer formulations where thermal stability and chemical resistance are required.
It contributes to advanced material production.
Chemical Research & Process Development
In industrial R&D environments, Triphenylphosphine Oxide is used for reaction optimization, purification studies, and catalyst system evaluation prior to scale-up production.
Safety & Handling Guidelines
- Store in a cool, dry, well-ventilated location
- Keep containers well-sealed
- Beware of inhaling dust.
- Prevent contact with skin and eyes
- Use gloves, goggles, and appropriate industrial protective equipment
- Handle under controlled industrial safety conditions
- Dispose of chemical waste according to regulatory standards
Always consult the MSDS before industrial handling.
Where to Buy Triphenylphosphine Oxide?
Triphenylphosphine Oxide Manufacturer
Triphenylphosphine Oxide is manufactured under controlled industrial standards to ensure consistent purity and performance for chemical and pharmaceutical industries.
Triphenylphosphine Oxide Supplier & Distributor
Triphenylphosphine Oxide is available in bulk industrial packaging formats. Buy Triphenylphosphine Oxide from Chemicalbull Pvt. Ltd., a trusted industrial chemicals supplier and distributor in India, ensuring reliable sourcing and compliant logistics support.
MSDS for Triphenylphosphine Oxide
The MSDS for Triphenylphosphine Oxide contains detailed information about the identification of hazards, safe handling techniques, storage specifications, as well as exposure control measures and emergency procedures for responding. It is important to read it before use.
Frequently Asked Questions (FAQs)
-
What is Triphenylphosphine Oxide used for?
Triphenylphosphine Oxide is used as an intermediate and by-product in phosphine-mediated reactions, catalyst systems, pharmaceutical synthesis, and specialty chemical manufacturing. -
Is Triphenylphosphine Oxide toxic?
It should be handled according to industry safety guidelines. While it's not particularly volatile, prolonged exposure could cause irritation. Always adhere to MSDS instructions. -
What is the solubility of Triphenylphosphine Oxide?
Triphenylphosphine Oxide is generally insoluble in water but soluble in many organic solvents such as chloroform, dichloromethane, and alcohols. -
What is the structure of Triphenylphosphine Oxide?
It consists of a phosphorus atom double-bonded to oxygen (P=O) and bonded to three phenyl (C₆H₅) groups. -
What is the chemical formula of Triphenylphosphine Oxide?
The chemical formula is C₁₈H₁₅OP.