Tri-N-Butylphosphine | 998-40-3

Description :

Overview of Tri-N-Butylphosphine

Tri-N-Butylphosphine (CAS: 998-40-3) is an important organophosphorus compound widely used in organic synthesis, catalyst systems, polymer chemistry, and pharmaceutical intermediate production. It typically appears as a colorless to pale yellow liquid with a strong odor and is known for its strong nucleophilic and reducing properties.

This compound is frequently used as a ligand and catalyst component in transition metal catalysis, particularly in reactions such as cross-coupling, polymerization, and carbon–carbon bond formation. Due to its reactivity and chemical stability, Tri-N-Butylphosphine is widely applied in fine chemical synthesis, pharmaceutical manufacturing, and specialty material production.

In organophosphorus chemistry, compounds such as Triphenylphosphine, Trioctylphosphine, and Tributyl Phosphate are also commonly used in catalysis, ligand chemistry, and industrial synthesis processes.

Applications of Tri-N-Butylphosphine

Chemical & Organic Synthesis

Tri-N-Butylphosphine is widely used as a reagent and catalyst component in organic reactions.

• Acts as a strong nucleophilic phosphine reagent

• Used in carbon–carbon bond forming reactions

• Supports fine chemical and intermediate synthesis

Catalysis & Ligand Chemistry

This compound is an important ligand for transition metal catalysts.

• Used in palladium-catalyzed reactions

• Helps stabilize metal catalyst complexes

• Improves reaction selectivity and efficiency

Polymer & Material Chemistry

Tri-N-Butylphosphine plays a role in polymer chemistry and advanced material synthesis.

• Used in polymerization catalyst systems

• Supports specialty resin and polymer development

• Applied in advanced materials research

Pharmaceutical & Fine Chemical Industry

It is frequently used in pharmaceutical intermediate synthesis.

• Used as a reagent in drug intermediate production

• Supports specialty chemical manufacturing

• Applied in complex organic reaction processes

Laboratory & Research Applications

This compound is widely used in academic and industrial R&D laboratories.

• Suitable for catalyst development studies

• Used in organophosphorus chemistry research

• Important reagent for advanced organic synthesis

Safety & Handling Guidelines

• Handle with protective gloves, goggles, and lab safety equipment

• Avoid inhalation of vapors or direct skin contact

• Use in well-ventilated laboratories or fume hoods

• Store in tightly sealed containers away from air and oxidizing agents

• Protect from heat, moisture, and strong oxidizers

Where to Buy Tri-N-Butylphosphine?

Tri-N-Butylphosphine Manufacturer

ChemicalBull supplies high-purity Tri-N-Butylphosphine suitable for organic synthesis, catalytic reactions, pharmaceutical intermediates, and specialty chemical manufacturing.

Tri-N-Butylphosphine Supplier & Distributor

• Available in laboratory and bulk industrial packaging

• Suitable for catalysis, polymer chemistry, and fine chemical production

• COA, MSDS, and technical documentation available

Tri-N-Butylphosphine MSDS

• May cause skin, eye, and respiratory irritation

• Flammable and air-sensitive organophosphorus compound

• Avoid exposure to open flames and oxidizing chemicals

• Use proper chemical protective equipment

• Refer to complete MSDS documentation for emergency procedures

Frequently Asked Questions (FAQs)

1. What is the molecular formula of Tri-N-Butylphosphine?

   Molecular Formula: C₁₂H₂₇P
   Molecular Weight: 202.32 g/mol
   
   

2. What is Tri-N-Butylphosphine used for?

   It is mainly used as a ligand in catalyst systems, reagent in organic synthesis, and intermediate in pharmaceutical and specialty chemical production.
   
   

3. Which industries use Tri-N-Butylphosphine?

   Common industries include pharmaceutical manufacturing, polymer chemistry, catalysis, and specialty chemical production.
   
   

4. Is Tri-N-Butylphosphine hazardous?

   Yes, it can cause irritation to skin, eyes, and respiratory system, and it should be handled using proper protective equipment and safety precautions.
   
   

5. Why is Tri-N-Butylphosphine important in catalysis?

   It acts as a strong electron-donating ligand, helping stabilize transition metal catalysts and improve reaction efficiency.