Tamoxifen Citrate | 54965-24-1

Description :

Overview of Tamoxifen Citrate

Tamoxifen Citrate is a selective estrogen receptor modulator (SERM) used for treating and preventing hormone receptor-positive breast cancer. Known for its dual action as an estrogen antagonist in breast tissue and an agonist in bone/uterus, Tamoxifen Citrate is widely used in oncology for breast cancer treatment, prevention in high-risk women, and as adjuvant therapy.

This API appears as a white to off-white crystalline powder. Its mechanism—competitive inhibition of estrogen binding to estrogen receptors in breast tissue—blocks estrogen-stimulated growth of hormone-sensitive breast cancer cells while providing estrogenic effects in other tissues.

Related products include Letrozole, Anastrozole, Raloxifene, and other hormonal anticancer agents used in breast cancer treatment and prevention.

Applications of Tamoxifen Citrate

Pharmaceutical API

• Used in hormone receptor-positive breast cancer treatment
• Applied in breast cancer prevention in high-risk women
• Used as adjuvant therapy following surgery/chemotherapy
• Applied to metastatic breast cancer
• Used in male breast cancer
• Applied in certain cases of infertility (off-label)

Formulation Development

• Used in immediate-release tablets
• Available in multiple strengths (10, 20 mg)
• Once or twice daily dosing
• Film-coated for improved stability
• Stable in solid dosage forms
• Generic formulations are widely available

Oncological Treatment

• Reduces breast cancer recurrence risk by ~40%
• Improves overall survival in ER+ breast cancer
• Reduces contralateral breast cancer risk
• Standard treatment duration: 5-10 years
• Well-established efficacy and safety profile
• Cost-effective cancer therapy

Safety & Handling Guidelines

• Cytotoxic—handle with appropriate precautions
• Avoid inhalation of fine powder
• Use gloves, goggles, and protective clothing during handling
• Store in a cool, dry place protected from light
• Follow COA and MSDS instructions strictly

Where to Buy Tamoxifen Citrate?

Tamoxifen Citrate Manufacturer

ChemicalBull offers Tamoxifen with high purity Citrate API , which meets the IP/EP/USP standards for quality for formulations of pharmaceuticals.

Tamoxifen Citrate Supplier & Distributor

• It is available in bulk packaging to make formulation units
• Highly pure and stable for production of oncology
• COA MSDS along with other documents for regulatory purposes available

MSDS

With detailed safety tips as well as hazard identification and instructions for storage.

Frequently Asked Questions (FAQs)

1. What is Tamoxifen Citrate used for?
   

   Used for treating hormone receptor-positive breast cancer, preventing breast cancer in high-risk women, and as adjuvant therapy post-surgery/chemotherapy.
   
   

2. How does Tamoxifen work?
   

   Acts as a selective estrogen receptor modulator (SERM), blocking estrogen effects in breast tissue (anti-estrogenic) while maintaining estrogenic effects in bone and uterus.
   
   

3. What is the typical dosage?
   

   Standard dose: 20 mg once daily; Prevention: 20 mg once daily for 5 years; Treatment duration: typically 5-10 years for adjuvant therapy.