Tacrolimus | 104987-11-3

Description :

Overview of Tacrolimus

Tacrolimus is a potent immunosuppressant API widely used in preventing organ transplant rejection and treating autoimmune skin disorders. Classified as a calcineurin inhibitor, it works by reducing T-cell activation and suppressing immune responses.

Recognized in major pharmacopeias, Tacrolimus is formulated into capsules, injections, ointments, and topical creams. During manufacturing, it is often processed with ChemicalBull products such as Lactose Monohydrate, Magnesium Stearate, Microcrystalline Cellulose, Propylene Glycol, and Ethanol to achieve stable dosage performance.

Applications of Tacrolimus

Pharmaceutical Formulations

• Essential ingredient in anti-rejection medicines used for kidney, liver, heart, and lung transplants

• Formulated into capsules, oral solutions, and injectable preparations

• Used with excipients like Magnesium Stearate and MCC

Dermatology & Topical Treatments

• Used in ointments and creams for:

  • Atopic dermatitis

  • Eczema

  • Vitiligo

  • Psoriasis

  • Chronic inflammatory skin conditions

• Compatible with Propylene Glycol and White Soft Paraffin

Research & Clinical Development

• Used in immunology research

• Supports studies on T-cell regulation and calcineurin inhibition

• Applied in bioequivalence and stability studies

Specialty Formulations

• Used in nano-delivery systems

• Employed in controlled-release and micro-emulsion formulations

Safety & Handling Guidelines

• Store in airtight containers at recommended temperatures

• Avoid inhalation and skin contact; use gloves, masks, and goggles

• Protect from light and moisture

• Follow MSDS for hazard details, toxicology data, and first-aid measures

Where to Buy Tacrolimus?

Tacrolimus Manufacturer

Produced under strict GMP and international regulatory standards to ensure high purity and consistent therapeutic profile.

Tacrolimus Supplier & Distributor

ChemicalBull supplies bulk Tacrolimus API to pharmaceutical companies, formulation facilities, and global importers. COA, MSDS, DMF support, and export-grade packaging available.

MSDS for Tacrolimus

MSDS includes:

• Hazard classification

• Exposure control guidelines

• Stability & reactivity information

• Storage and handling precautions

• Emergency response and disposal instructions

Frequently Asked Questions (FAQs)

1. What is Tacrolimus used for?

   It is used as an immunosuppressant to prevent organ transplant rejection and treat skin conditions like eczema.
   
   

2. Is Tacrolimus used topically?

   Yes, it is used in ointment/cream form for dermatological disorders such as atopic dermatitis.
   
   

3. Do you provide Tacrolimus in bulk?

   Yes, ChemicalBull supplies bulk Tacrolimus API with COA, MSDS, and export-compliant packaging.