Sodium Aminosalicylate | 6018-19-5

Description :

Overview of Sodium Aminosalicylate

Sodium Aminosalicylate (Sodium PAS) is a second-line antituberculosis treatment that is employed in conjunction therapy to treat tuberculosis that is resistant to treatment. It is known due to its bacteriostatic effects against Mycobacterium tuberculosis, as well as its role in multidrug-resistant (MDR) treatment for TB.

Sodium Aminosalicylate is a key element of sophisticated TB treatment protocols.

This API appears as a white to off-white or slightly yellow crystalline powder with characteristic properties. Its mechanism—inhibition of folic acid synthesis and iron uptake in mycobacteria—provides bacteriostatic activity and is particularly valuable in combination with other anti-TB drugs.

Related products include Isoniazid, Rifampicin, Ethambutol, and other anti-tuberculosis medications used in TB treatment protocols.

Applications of Sodium Aminosalicylate

Pharmaceutical API

• Used in second-line anti-tuberculosis therapy
• Essential component of MDR-TB treatment regimens
• Applied when resistance to first-line drugs exists
• Used in combination with other anti-TB medications
• Applied to extensively drug-resistant (XDR) TB
• Part of the WHO-recommended MDR-TB treatment protocols

Formulation Development

• Used in tablets and granules for oral administration
• Often formulated as enteric-coated or delayed-release
• Large doses required (8-12 g daily in divided doses)
• Requires protection from light and air
• Buffered formulations reduce gastric irritation
• Stable in properly formulated products

Tuberculosis Treatment

• Provides bacteriostatic activity against M. tuberculosis
• Helps prevent the development of resistance to companion drugs
• Used in lengthy treatment courses (18-24 months or longer)
• Requires monitoring for side effects and therapeutic response
• Important option when first-line drugs fail or are contraindicated

Safety & Handling Guidelines

• Do not inhale fine powder
• Wear gloves, goggles as well as protective clothes when handling
• Guard against sunlight and exposure to air
• Keep in tightly sealed and light-resistant container under dry, cool conditions.
• Use COA as well as MSDS directions completely

Where can I buy sodium Aminosalicylate?

Sodium Aminosalicylate Manufacturer

ChemicalBull supplies pure Sodium Aminosalicylate API that is compliant with USP/IP/EP quality standards for formulations in pharmaceuticals.

Sodium Aminosalicylate Supplier & Distributor

• In bulk packaging for formula units
• High-purity and stable to make anti-TB medications
• Needs to be stored in controlled requirements
• COA MSDS as well as regulatory documentation are provided.

MSDS

Includes detailed safety instructions, hazard identification, and storage guidelines.

Frequently Asked Questions (FAQs)

1. What is Sodium Aminosalicylate used for?
   

   It is used as a second-line anti-tuberculosis medication in the treatment of drug-resistant TB, particularly MDR-TB and XDR-TB.
   
   

2. How does Sodium Aminosalicylate work?
   

   It inhibits folic acid synthesis and iron metabolism in mycobacteria, providing bacteriostatic activity against M. tuberculosis.
   
   

3. What is the dosage of Sodium Aminosalicylate?
   

   Typical adult dose is 8-12 grams daily in 2-3 divided doses, usually given with food to reduce GI side effects.