Entecavir Anhydrous | 142217-69-4

Description :

Overview of Entecavir Anhydrous

It is a powerful antiviral agent. Anhydrous is a powerful antiviral guanosine nucleoside analogue employed to treat persistent hepatitis B virus (HBV) disease. It is renowned for its effectiveness against viruses, and its lower resistance profiles. Entecavir Anhydrous is frequently utilised in hepatology for the long-term care of persistent HBV infection, in treatment-naive patients and those who are resistant to lamivudine.

The API manifests as an off-white to white crystalline powder that is extremely stable in storage under controlled conditions. Its mechanism--selective inhibition of HBV polymerase (reverse transcriptase)--blocks viral DNA synthesis and replication, effectively suppressing HBV viral load and improving liver function.

Related products include Tenofovir, Lamivudine, Adefovir, and other nucleoside/nucleotide analogue antivirals used in the treatment of chronic hepatitis B and HIV.

Applications of Entecavir Anhydrous

Pharmaceutical API

• Used in antiviral medications for chronic hepatitis B treatment
• Effective in both HBeAg-positive and HBeAg-negative chronic HBV infection
• Treats lamivudine-resistant HBV strains
• Reduces viral load and normalises liver enzymes
• Decreases progression to cirrhosis and hepatocellular carcinoma

Formulation Development

• Used in film-coated tablets and oral solutions
• Requires once-daily dosing on an empty stomach
• Offers excellent oral bioavailability
• Stable in solid and liquid dosage forms
• Available in pediatric and adult formulations

Hepatological Treatment

• Provides sustained viral suppression with long-term therapy
• High genetic barrier to resistance development
• Improves histological outcomes and reduces liver fibrosis
• Well-tolerated with a favourable safety profile
• First-line therapy for chronic hepatitis B

Safety & Handling Guidelines

• Avoid inhalation of fine powder
• Use gloves, goggles, and protective clothing during handling
• Potent antiviral—handle in controlled environments
• Store in a cool, dry place away from light and moisture
• Follow COA and MSDS instructions strictly

Where to Buy Entecavir Anhydrous?

Entecavir Anhydrous Manufacturer

ChemicalBull supplies high-purity Entecavir Anhydrous API that meets IP/EP/USP quality standards for pharmaceutical formulations.

Entecavir Anhydrous Supplier & Distributor

• Available in bulk packing for formulation units
• Stable and high-purity grade for research and production
• COA, MSDS, and regulatory documents provided

MSDS

Includes detailed safety instructions, hazard identification, and storage guidelines.

Frequently Asked Questions (FAQs)

1. What is Entecavir Anhydrous?
   

   Entecavir Anhydrous is the anhydrous (water-free) form of Entecavir, a nucleoside analogue antiviral medication used to treat chronic hepatitis B virus infection.
   
   

2. What is Entecavir Anhydrous used for?
   

   It is used for long-term treatment of chronic hepatitis B infection in adults and children, including patients with compensated and decompensated liver disease.
   
   

3. How does Entecavir work?
   

   It competes with natural substrates and inhibits HBV polymerase, blocking viral DNA synthesis, reverse transcription, and viral replication.