Simethicone | 8050-81-5

Description :

Overview of Simethicone

Simethicone is an anti-foaming agent used for relieving symptoms of gas, bloating, and flatulence in the gastrointestinal tract. Known for its ability to reduce surface tension of gas bubbles, allowing them to coalesce and be expelled more easily, Simethicone is widely used in antacid formulations, anti-gas products, and as an adjunct in gastrointestinal diagnostic procedures.

This compound appears as a clear to translucent viscous liquid or emulsion with characteristic properties. Its mechanism—reducing surface tension of gas bubbles in the GI tract—allows smaller bubbles to combine into larger ones that can be more easily eliminated through belching or passing gas.

Related products include Activated Charcoal, Digestive Enzymes, and other anti-gas and digestive aid agents used in gastrointestinal symptom relief.

Applications of Simethicone

Pharmaceutical Applications

• Used in anti-gas medications for gas, bloating, and flatulence relief
• Combined with antacids for comprehensive digestive symptom relief
• Applied in infant colic formulations (gas drops)
• Used as premedication before endoscopy and ultrasound procedures
• Applied in postoperative gas pain management
• Used in the treatment of functional dyspepsia treatment

Formulation Development

• It is used in chewable suspensions for oral use, tablets, and soft gels
• In emulsion form or liquid form
• Most often, HTML0 is combined with magnesium hydroxide, calcium carbonate, and aluminum hydroxide
• Formulations for children are offered in chewables and drops
• Stable over a broad pH range
• Compatible with a variety of antacids and ingredients for digestive aids

Gastrointestinal Treatment

• Gives immediate relief from discomfort caused by gas.
• Does not prevent gas formation but aids in elimination
• and is safe for use over a long period of time with minimal absorption into the system.
• It is appropriate for people of all ages, including babies
• No significant drug interactions
• are a local effect in the GI tract with no effects on the system.

Safety and Guidelines for Handling

• Make sure you wear gloves and appropriate clothing when handling ng
• Storage in tightly sealed containers
• Avoid extreme temperatures
• Use the COA as well as the MSDS directions strictly.

Where to Buy Simethicone?

Simethicone Manufacturer

ChemicalBull supplies high-purity Simethicone that meets IP/EP/USP quality standards for pharmaceutical applications.

Simethicone Supplier & Distributor

• Available in bulk packing for formulation units
• Multiple viscosity grades available
• Stable emulsions form for various applications
• COA, MSDS, and regulatory documents provided

MSDS

Includes detailed safety instructions, hazard identification, and storage guidelines.

Frequently Asked Questions (FAQs)

1. What is Simethicone used for?
   

   Simethicone is used to relieve gas, bloating, pressure, and discomfort in the stomach and intestines; treat infant colic; and reduce gas interference in diagnostic procedures.
   
   

2. How does Simethicone work?
   

   It reduces the surface tension of gas bubbles in the digestive tract, causing them to coalesce into larger bubbles that are more easily expelled through belching or flatulence.
   
   

3. Is Simethicone safe for infants?
   

   Yes, simethicone is considered safe for infants and is commonly used for infant colic and gas relief, available in specially formulated drops.