Poloxamer 407 | 2594628

Cas No :

2594628

Form :

Solid 

Molecular Weight :

12600 G/Mol

Molecular Formula :

C572H1146O259

Melting Point :

56 °C

Boiling Point :

350 °C

Solubility :

Soluble In Water

Flash Point :

230 °C

Description :

Overview of Poloxamer 407

Poloxamer 407 is a non-ionic triblock copolymer composed of poly(ethylene oxide) and poly(propylene oxide). It is widely used as a surfactant, emulsifier, solubilizer, and rheology modifier in pharmaceutical, cosmetic, and industrial formulations. Poloxamer 407 is known for its thermoreversible gelation behavior, high purity, and excellent biocompatibility, making it suitable for advanced formulation systems.

In industrial and pharmaceutical applications, Poloxamer 407 is valued for consistent molecular weight distribution, stability, and compatibility with active ingredients. It is frequently used alongside Poloxamer 188, PEG derivatives, and Propylene Glycol, available on ChemicalBull, enabling seamless formulation and product interlinking.

 

Applications of Poloxamer 407

Pharmaceutical Formulations

  • Used as a solubilizer and stabilizer in oral, topical, and injectable formulations

  • Supports controlled drug release and enhanced bioavailability


Cosmetics & Personal Care

  • Acts as an emulsifier and thickening agent in creams, gels, and lotions

  • Improves texture, spreadability, and product stability


Drug Delivery Systems

  • Used in thermosensitive gels and sustained-release systems

  • Enhances drug encapsulation and delivery efficiency


Industrial & Speciality Applications

  • Used as a surfactant in cleaning formulations and speciality chemicals

  • Provides excellent wetting and dispersion properties

 

Safety & Handling Guidelines

  • Handle using standard industrial and laboratory PPE

  • Avoid inhalation of dust during handling

  • Store in a cool, dry place away from direct heat and moisture

  • Keep containers tightly closed when not in use

  • Follow MSDS, SDS, and standard safety guidelines

 

Where to Buy Poloxamer 407?

Poloxamer 407 Manufacturer

ChemicalBull supplies high-quality Poloxamer 407 suitable for pharmaceutical, cosmetic, and industrial applications.


Poloxamer 407 Supplier & Distributor

  • Bulk and customized packaging options

  • Pharmaceutical and industrial grade material

  • COA, TDS & MSDS available

  • Reliable supply for manufacturers, formulators, and R&D units

  • Explore related products: Poloxamer 188, PEG 400, Propylene Glycol

 

Poloxamer 407 MSDS

The Material Safety Data Sheet (MSDS) provides detailed information on handling, storage, exposure controls, and emergency measures. Always consult the MSDS before formulation or industrial use.

 

Frequently Asked Questions (FAQs)

  1. What is Poloxamer 407 used for?

    It is used as a surfactant, solubilizer, emulsifier, and gel-forming agent in pharmaceutical, cosmetic, and industrial formulations.

  2. Is Poloxamer 407 safe for pharmaceutical use?

    Yes, it is widely used in pharmaceutical formulations due to its biocompatibility and non-ionic nature.

  3. Can Poloxamer 407 form gels?

    Yes, it exhibits thermoreversible gelation, forming gels at higher temperatures.