N,N-Dicyclohexylcarbodiimide | 538-75-0

Description :

Overview of N, N-Dicyclohexylcarbodiimide

N, N-Dicyclohexylcarbodiimide (DCC) is a widely used coupling reagent in organic synthesis and peptide chemistry. The reagent is known for its efficacy in the formation of amide bonds as well as esters. DCC is a key component in the research of pharmaceuticals, API synthesis, and the production of fine chemicals.

This chemical appears as a white to pale yellow crystalline solid with a characteristic odor. Its mechanism—activation of carboxylic acids for nucleophilic substitution—makes it indispensable in peptide synthesis and in the manufacture of pharmaceutical intermediates.

Related products include N, N-Diisopropylcarbodiimide (DIC), 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC), and other carbodiimide coupling agents used in synthetic chemistry.

Applications of N, N-Dicyclohexylcarbodiimide

Pharmaceutical Synthesis

• Used as a coupling reagent in peptide and protein synthesis
• Facilitates the formation of amide bonds in API manufacturing
• Essential in the synthesis of pharmaceutical intermediates
• Enables efficient esterification reactions

Research & Development

• Widely used in academic and industrial research laboratories
• Key reagent in organic synthesis and medicinal chemistry
• Applied in polymer chemistry and material science
• Used in the synthesis of complex organic molecules

Fine Chemical Production

• Employed in the synthesis of specialty chemicals
• Used in the production of agrochemicals and advanced intermediates
• Facilitates condensation reactions in multi-step synthesis
• Offers high yield and selectivity in coupling reactions

Safety & Handling Guidelines

• Avoid contact with skin, eyes, and mucous membranes
• Use in well-ventilated areas or under a fume hood
• Wear appropriate PPE, including gloves, goggles, and a lab coat
• Store in tightly closed containers in a cool, dry place
• Follow COA and MSDS instructions strictly
• Moisture-sensitive—handle under anhydrous conditions

Where to Buy N, N-Dicyclohexylcarbodiimide?

N, N-Dicyclohexylcarbodiimide Manufacturer

ChemicalBull supplies high-purity N, N-Dicyclohexylcarbodiimide that meets technical and research-grade quality standards for synthetic applications.

N, N-Dicyclohexylcarbodiimide Supplier & Distributor

• Available in various pack sizes for laboratory and industrial use
• High-purity grade for research and production
• COA, MSDS, and technical specifications provided

MSDS

Includes detailed safety instructions, hazard identification, and storage guidelines.

Frequently Asked Questions (FAQs)

1. What is N, N-Dicyclohexylcarbodiimide used for?
   

   It is primarily used as a coupling reagent in peptide synthesis and organic chemistry.
   
   

2. Is DCC moisture-sensitive?
   

   Yes, it should be stored and handled under anhydrous conditions to maintain its reactivity.
   
   

3. What are the safety concerns with DCC?
   

   It can cause skin and eye irritation and should be handled with appropriate protective equipment in well-ventilated areas.