Zoledronic Acid | 165800-06-6
Cas No :
165800-06-6
Form :
Solid
Molecular Weight :
272.11 G/Mol
Molecular Formula :
C5H12N2O8P2
Melting Point :
198 °C
Boiling Point :
300 °C
Solubility :
Sparingly Soluble In Water
Flash Point :
180 °C
Description :
Overview of Zoledronic Acid
Zoledronic Acid is a high-quality pharmaceutical bisphosphonate that is extensively used for the treatment of bone-related diseases. It is well-known due to its high affinity to bone tissue as well as its potent reduction in bone Resorption.
In the pharmaceutical industry, Zoledronic Acid is valued because of its specific effect on osteoclast function and its lasting therapeutic effect. It is often utilised in regulated oncology as well as osteoporosis treatments in which precise dosage and strict quality control are essential. As a chemical in the pharmaceutical industry, Zoledronic Acid plays a critical role in the management of bone metabolism.
Zoledronic Acid is manufactured and supplied in India for pharmaceutical use under controlled regulatory standards.
Applications of Zoledronic Acid
Bone Disorders & Oncology Use
Zoledronic Acid is mostly used for treating osteoporosis, Paget's Disease of bone, as well as bone-related complications that are caused by cancer. It can help reduce the loss of bone, strengthen bone structure, and decrease the chance of breaking.
In oncology-related formulations, it is often evaluated alongside compounds such as Alendronate Sodium for bone resorption management.
Pharmaceutical Chemistry & Mechanism of Action
The mechanism of action is to inhibit the mevalonate pathway within osteoclasts. This results in decreased osteoclasts' bone resorption as well as an increase in density. The term bisphosphonate is used to describe it because of its phosphonate group that binds tightly with bone minerals.
It is also compared with other bisphosphonates such as Ibandronic Acid in pharmaceutical research and formulation development.
Clinical & Hospital-Based Pharmaceutical Use
Zoledronic Acid is commonly administered in hospital and clinical settings via intravenous infusion. Its long duration of action allows for infrequent dosing under strict medical supervision. It is also used in combination therapy regimens with supportive agents such as Calcium Gluconate to maintain mineral balance during treatment.
Safety & Handling Guidelines
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Keep it in a cool, humid, dry and well-controlled area
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Seal containers well and keep them clearly labelled
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Beware of inhaling dust or aerosols
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Avoid direct contact with skin and eyes
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Use protective gloves, goggles, and appropriate pharmaceutical-grade protective clothing
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Handle under strictly controlled pharmaceutical and clinical conditions
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Dispose of waste according to hazardous pharmaceutical waste regulations
Where to Buy Zoledronic Acid?
Zoledronic Acid Manufacturer
Zoledronic Acid is manufactured for pharmaceutical applications where high purity, consistent potency, and compliance with bisphosphonate drug standards are required.
Zoledronic Acid Supplier & Distributor
Zoledronic Acid pharma chemical supplier in India provides pharmaceutical-grade material for hospitals, oncology centres, and formulation manufacturers. As a pharmaceutical chemicals supplier and distributor, Chemicalbull Pvt. Ltd. supports customers with reliable sourcing and standard documentation.
MSDS for Zoledronic Acid
The MSDS for Zoledronic Acid provides detailed information on hazards, safe handling practices, storage conditions, exposure controls, first-aid measures, and emergency response procedures. Always review the MSDS before pharmaceutical use.
Frequently Asked Questions (FAQs)
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Is Zoledronic Acid a bisphosphonate?
Yes, Zoledronic Acid is a nitrogen-containing bisphosphonate used to inhibit bone resorption. -
What is the chemical name for Zoledronic Acid?
The chemical name for Zoledronic Acid is (1-hydroxy-2-imidazol-1-ylethylidene) bisphosphonic acid. -
What is Zoledronic Acid used for?
Zoledronic Acid is used to treat osteoporosis, bone metastases, Paget’s disease of bone, and other conditions involving excessive bone loss. -
What is the most common side effect of Zoledronic Acid?
The most common zoledronic acid side effect is flu-like symptoms, including fever, muscle pain, and fatigue, following administration. -
Where can I buy Zoledronic Acid in India?
Zoledronic Acid can be sourced from Chemicalbull, a pharmaceutical chemical supplier in India that provides regulated bisphosphonate compounds with standard documentation.