Dimethyl Sulfoxide | 67-68-5

Cas No :

67-68-5

Form :

Liquid

Molecular Weight :

78.13 G/Mol

Molecular Formula :

C2H6OS

Boiling Point :

189 °C

Melting Point :

18.5 °C

Flash Point :

94 °C

Solubility :

Miscible With Water; Soluble In Many Organic Solvents

Description :

Overview of Dimethyl Sulfoxide

Dimethyl Sulfoxide (DMSO) is a pharmaceutical-grade polar aprotic solvent widely used in pharmaceutical manufacturing, formulation development, and drug delivery research. It is known for its exceptional solvating power and ability to enhance transdermal and cellular penetration of active compounds.

In pharmaceutical production, Dimethyl Sulfoxide is valued for its high purity, chemical stability, and compatibility with a wide range of active pharmaceutical ingredients. It is manufactured under controlled conditions to meet pharmacopeial and regulatory standards.

As a pharma chemical, Dimethyl Sulfoxide functions primarily as a solvent, carrier, and formulation aid rather than as a therapeutic API.


Applications of Dimethyl Sulfoxide

Pharmaceutical Solvent & Formulation Aid

Dimethyl Sulfoxide is used as a solvent in pharmaceutical formulations where poor water solubility of active ingredients is a challenge. It supports dissolution and uniform distribution of APIs in liquid and semi-solid dosage forms.

Drug Delivery & Penetration Enhancement

Dimethyl Sulfoxide is widely used in pharmaceutical research and topical formulations to enhance penetration of active compounds through biological membranes. Its carrier properties improve delivery efficiency of drugs applied via dermal or mucosal routes.

Cryopreservation & Biopharmaceutical Processing

Dimethyl Sulfoxide is used in pharmaceutical and biopharmaceutical processing as a cryoprotective agent. It helps preserve cell integrity during freezing and storage of biological materials used in regulated pharmaceutical research.

Regulated Pharmaceutical Manufacturing Use

Dimethyl Sulfoxide is manufactured as a high-purity pharmaceutical raw material with strict control over residual impurities and moisture content. It is suitable for GMP-compliant pharmaceutical and biopharmaceutical production environments.

In solvent and formulation-support systems, it is often evaluated alongside Polyethylene Glycol, Propylene Glycol, and Ethanol for comparative solvency and compatibility.


Safety & Handling Guidelines

  • Store in a cool, dry, and controlled environment

  • Protect from contamination and excessive heat

  • Keep containers tightly sealed and clearly labelled

  • Avoid prolonged skin contact

  • Use appropriate personal protective equipment

  • Handle under controlled pharmaceutical manufacturing conditions

  • Dispose of waste according to regulatory guidelines


Where to Buy Dimethyl Sulfoxide?

Dimethyl Sulfoxide Manufacturer

Dimethyl Sulfoxide is manufactured for pharmaceutical and biopharmaceutical applications where controlled purity, consistent quality, and regulatory compliance are required.

Dimethyl Sulfoxide Supplier & Distributor

Pharmaceutical-grade Dimethyl Sulfoxide is supplied in suitable packaging for formulation manufacturers and research facilities. As a pharmaceutical chemicals supplier and distributor, Chemicalbull Pvt. Ltd. supports reliable sourcing with standard documentation.


MSDS for Dimethyl Sulfoxide

The MSDS for Dimethyl Sulfoxide provides information on hazards, handling precautions, storage conditions, exposure controls, and emergency response measures. It should be reviewed before pharmaceutical manufacturing or research use.


Frequently Asked Questions (FAQs)

  1. What is Dimethyl Sulfoxide used for?

    Dimethyl Sulfoxide is used in pharmaceutical formulations as a solvent, penetration enhancer, and processing aid.

  2. Is Dimethyl Sulfoxide an API?

    No, Dimethyl Sulfoxide is primarily used as a pharmaceutical solvent and formulation aid rather than an active pharmaceutical ingredient.

  3. Are there side effects associated with Dimethyl Sulfoxide?

    Dimethyl sulfoxide side effects may occur with improper handling or exposure and include skin irritation or odour-related effects.

  4. Is Dimethyl Sulfoxide suitable for regulated pharmaceutical manufacturing?

    Yes, pharmaceutical-grade Dimethyl Sulfoxide is widely used in GMP-compliant pharmaceutical and biopharmaceutical production.

  5. Can Dimethyl Sulfoxide be used in topical formulations?

    Yes, it is commonly used to support penetration and solubility in topical pharmaceutical products.