Diethylaminosulfur Trifluoride

Description :

Overview of Diethylaminosulfur Trifluoride

Diethylaminosulfur Trifluoride (DAST) (CAS 38078-09-0) is extremely reactive and is extensively used in pharmaceuticals, organic synthesis, agricultural chemicals, and industrial chemical transformations.

It appears as a clear to pale yellow liquid and is known for its strong ability to convert alcohols, carbonyl compounds, and carboxylic acids into their corresponding fluorinated derivatives.

DAST is a key reagent in fine chemical manufacturing due to its efficiency, selectivity, and ability to perform smooth fluorination under mild conditions. It is extensively used in producing API intermediates, fluorinated agroactives, speciality chemicals, and research chemicals.

Related products available on ChemicalBull: Trifluoromethanesulfonic Anhydride, Sulfuryl Fluoride, Trifluoroacetic Anhydride – used in fluorination, halogenation, and advanced organic synthesis.

 

Applications of Diethylaminosulfur Trifluoride (DAST)

Pharmaceutical Intermediates

  • Used for introducing fluorine into drug molecules
  • Helps in manufacturing APIs with enhanced stability and bioactivity
  • Suitable for converting alcohols to alkyl fluorides and carbonyls to gem-difluorides

Agrochemical Synthesis

  • Applied in producing fluorinated herbicides, pesticides, and fungicides
  • Supports the synthesis of fluorine-containing agro intermediates

Speciality Chemical Manufacturing

  • Used in fluorination reactions for fine chemicals
  • Essential in transforming hydroxyl groups to fluorinated variants
  • Useful for the synthesis of high-value speciality intermediates

Organic Synthesis & Research

  • Widely used in academic and industrial R&D labs
  • Suitable for fluorination of alcohols, amides, and sulfoxides
  • Applied in developing fluorine-containing building blocks

Safety & Handling Guidelines

General Handling

  • Highly reactive—avoid contact with moisture
  • Use gloves, goggles, and full protective equipment
  • Handle under dry, well-ventilated conditions
  • Store in airtight containers away from heat and humidity
  • Follow COA and MSDS guidelines strictly

 

MSDS

  • Refer to the full MSDS for spill control and emergency response

 

Where to Buy Diethylaminosulfur Trifluoride?

Diethylaminosulfur Trifluoride Manufacturer

ChemicalBull supplies high-purity Diethylaminosulfur Trifluoride (DAST) suitable for pharmaceuticals, agrochemicals, and industrial fluorination processes.

Diethylaminosulfur Trifluoride Supplier & Distributor

  • Available in moisture-sealed laboratory and bulk packaging
  • Ideal for fine chemical and speciality synthesis
  • COA, MSDS, and technical specifications provided

 

Frequently Asked Questions (FAQs)

What is the molecular formula of Diethylaminosulfur Trifluoride?

  • Molecular Formula: C₄H₁₀F₃NS
  • Molecular Weight: 161.19 g/mol

What is Diethylaminosulfur Trifluoride used for?

Used mainly as a fluorinating reagent in pharmaceuticals, agrochemicals, and organic synthesis.

Is Diethylaminosulfur Trifluoride hazardous?

Yes. It is reactive and moisture-sensitive. Handle with extreme care using PPE and follow MSDS guidelines.