Diethyl Acetamidomalonate | 1068-90-2

Description :

Overview of Diethyl Acetamidomalonate

Diethyl Acetamidomalonate (DEAM) is an important organic compound widely utilized in agrochemical, pharmaceutical, and fine chemical synthesis. It is an amino malonate derivative that is protected, which plays an important part in the preparation of heterocyclic compounds.

Due to its active methylene group and acetamido functionality, Diethyl Acetamidomalonate is highly valued in carbon–carbon bond formation reactions and advanced organic synthesis. It serves as a key building block in the preparation of substituted amino acids and specialty nitrogen-containing compounds.

Diethyl Acetamidomalonate is primarily utilized in research laboratories, pharmaceutical manufacturing, and specialty chemical production.

Applications of Diethyl Acetamidomalonate

Pharmaceutical Intermediates

Diethyl Acetamidomalonate is widely used in the synthesis of α-amino acids and drug intermediates. It acts as a precursor in the preparation of glycine derivatives and other substituted amino acid structures.

In pharmaceutical processes, it may be used with reagents such as Sodium Ethoxide, Acetyl Chloride, and Hydrochloric Acid during hydrolysis and decarboxylation steps.

Amino Acid & Peptide Synthesis

Diethyl Acetamidomalonate is a key intermediate in the synthesis of amino acids via hydrolysis and alkylation reactions. The compound permits controllable introduction of the side chain prior to deprotection.

Agrochemical & Fine Chemical Manufacturing

Diethyl Acetamidomalonate is applied in the development of agrochemical intermediates and specialty organic compounds. Its reactive ester groups make it suitable for further functionalization.

Research & Advanced Organic Synthesis

In laboratory and R&D environments, Diethyl Acetamidomalonate is used in carbon–carbon bond formation reactions, heterocycle synthesis, and substituted acetic acid derivatives.

Safety & Handling Guidelines

• Store in a cool, dry, well-ventilated area
• Make sure containers are tightly sealed and clearly labeled
• Beware of inhaling dust or vapours
• Avoid contact with eyes and skin
• Use protective gloves, goggles, and suitable laboratory clothing
• Handle under controlled industrial conditions
• Dispose of waste according to regulatory guidelines

Always review the MSDS before handling.

Where to Buy Diethyl Acetamidomalonate?

Diethyl Acetamidomalonate Manufacturer

Diethyl Acetamidomalonate is manufactured under controlled production standards to ensure high purity and consistent performance for pharmaceutical and specialty chemical applications.

Diethyl Acetamidomalonate Supplier & Distributor

Diethyl Acetamidomalonate is available in laboratory and bulk packaging. Buy Diethyl Acetamidomalonate from Chemicalbull Pvt. Ltd., a trusted industrial chemicals supplier and distributor in India, ensuring reliable sourcing and quality assurance.

MSDS for Diethyl Acetamidomalonate

The MSDS for Diethyl Acetamidomalonate provides detailed information on hazard identification, safe handling practices, storage requirements, exposure controls, and emergency response measures. Always consult the MSDS before industrial or laboratory use.

Frequently Asked Questions (FAQs)

1. What are the uses of Diethyl Acetamidomalonate?
   

   Diethyl Acetamidomalonate is used in amino acid synthesis, pharmaceutical intermediates, agrochemical manufacturing, and advanced organic synthesis.
   
   

2. What is the CAS number of Diethyl Acetamidomalonate?
   

   The CAS number of Diethyl Acetamidomalonate is 1068-90-2.
   
   

3. How is Diethyl Acetamidomalonate synthesized?
   

   Diethyl Acetamidomalonate is typically synthesized by acetylation of diethyl aminomalonate or through controlled acylation reactions involving malonate derivatives under regulated conditions.
   
   

4. Is Diethyl Acetamidomalonate used in amino acid production?
   

   Yes, it is widely used as a protected intermediate in the preparation of substituted amino acids through alkylation, hydrolysis, and decarboxylation steps.
   
   

5. Is Diethyl Acetamidomalonate suitable for pharmaceutical manufacturing?
   

   Yes, high-purity grades of Diethyl Acetamidomalonate are suitable for pharmaceutical and fine chemical manufacturing applications.