4-Fluorobenzoyl Chloride | 403-43-0

Cas No :

403-43-0

Synonyms :

Form :

Liquid

Molecular Weight :

158.55 g/mol

Molecular Formula :

C7H4CLFO

Boiling Point :

202 °C

Melting Point :

-25 °C

Flash Point :

85 °C

Solubility :

Slightly soluble in water, soluble in organic solvents

Description :

4-Fluorobenzoyl Chloride Supplier & Distributor In India

ChemicalBull is a trusted 4-Fluorobenzoyl Chloride supplier, distributor, and exporter in India, supporting sourcing for pharmaceutical intermediate developers, fine chemical manufacturers, organic synthesis units, research laboratories, chemical distributors, wholesalers, and global B2B buyers.

4-Fluorobenzoyl Chloride, also known as p-Fluorobenzoyl Chloride, is a fluorinated aromatic acid chloride with CAS number 403-43-0. It is used as an acylating reagent for preparing fluorinated amides, esters, aromatic ketones, and specialty chemical intermediates.

Contact ChemicalBull for a 4-Fluorobenzoyl Chloride Quote — Share your required quantity, purity, packing size, and delivery location to request bulk pricing and supply details.


Overview of 4-Fluorobenzoyl Chloride

4-Fluorobenzoyl Chloride has the molecular formula C7H4ClFO and a molecular weight of 158.56 g/mol. Its structure contains an acid chloride group attached to a benzene ring, with fluorine in the para position.

The compound is generally a liquid at normal room temperature, with a reported melting range of approximately 10–12°C. Its reactive acid chloride group enables the introduction of a 4-fluorobenzoyl group into suitable target compounds.

Buyers should confirm assay, isomer identity, impurity profile, moisture control, appearance, packaging, and storage requirements before procurement. Review the offered specification and batch COA against the intended synthesis process.


Applications of 4-Fluorobenzoyl Chloride

Fluorinated Amide Preparation

4-Fluorobenzoyl Chloride can react with suitable amines to prepare 4-fluorobenzamide derivatives. These reactions support fine chemical synthesis and selected pharmaceutical intermediate development routes.

Fluorinated Ester Preparation

The compound can acylate suitable alcohols and phenols to form 4-fluorobenzoate esters. Process developers should select conditions that achieve the required conversion while controlling hydrolysis and other side reactions.

Aromatic Ketone Synthesis

4-Fluorobenzoyl Chloride is used in suitable Friedel–Crafts acylation reactions to prepare aromatic ketones. A documented example is its reaction with 2,6-dimethylnaphthalene to form a bis(4-fluorobenzoyl) derivative.

Pharmaceutical & Fine Chemical Intermediate Development

Intermediate developers can evaluate 4-Fluorobenzoyl Chloride for synthesis routes requiring a para-fluorinated benzoyl group. Suitability depends on the target structure, reaction sequence, and required impurity limits.

Laboratory & Research Use

Research laboratories use 4-Fluorobenzoyl Chloride for acylation studies, synthetic route development, and fluorinated compound preparation. Researchers should select a grade suitable for their experimental and analytical requirements.


4-Fluorobenzoyl Chloride Supply Support For Industrial Buyers

ChemicalBull supports 4-Fluorobenzoyl Chloride sourcing for pharmaceutical intermediate companies, fine chemical manufacturers, organic synthesis units, laboratories, distributors, wholesalers, and export customers.

As a supplier, distributor, and exporter, ChemicalBull assists buyers with specification enquiries, packing options, quantity requirements, and documentation requests. Buyers can request COA, TDS, SDS or MSDS, and applicable export documents for the offered grade.


Why Choose ChemicalBull For 4-Fluorobenzoyl Chloride?

ChemicalBull helps B2B buyers coordinate 4-Fluorobenzoyl Chloride sourcing according to their required specification, order quantity, packaging needs, and delivery schedule.

Our team supports bulk quotation enquiries, document assistance, domestic dispatch coordination, export requirements, and repeat procurement planning. Share your required assay and impurity limits so the offered material can be reviewed before order confirmation.


4-Fluorobenzoyl Chloride MSDS & Handling

4-Fluorobenzoyl Chloride can cause severe skin burns and eye damage. It is a combustible liquid and may be corrosive to metals. Avoid direct contact and breathing vapour or mist. Use suitable chemical-resistant gloves, protective clothing, eye and face protection, and effective local exhaust ventilation.

Protect the material from water and moisture because acid chlorides can hydrolyse and release hydrogen chloride. Keep containers tightly closed and away from heat and ignition sources. Follow the supplied SDS for compatible packaging, storage conditions, incompatible chemicals, spill response, first aid, and disposal instructions.


Related Products

Buyers sourcing 4-Fluorobenzoyl Chloride may also enquire about related aromatic acid chlorides and synthesis intermediates from ChemicalBull.

Request a Quote for 4-Fluorobenzoyl Chloride

Need 4-Fluorobenzoyl Chloride CAS 403-43-0 for fluorinated amides, esters, aromatic ketones, intermediate development, or laboratory research?

Send your required quantity, purity, impurity limits, packing size, application, delivery location, and document needs to ChemicalBull. Our team will confirm the offered specification, current availability, bulk pricing, and supply options for domestic or export orders.


Frequently Asked Questions

  1. What is 4-Fluorobenzoyl Chloride?

    4-Fluorobenzoyl Chloride is a fluorinated aromatic acid chloride also known as p-Fluorobenzoyl Chloride. It is used as an acylating reagent in organic synthesis.

  2. What is the CAS number of 4-Fluorobenzoyl Chloride?

    The CAS number is 403-43-0. Its molecular formula is C7H4ClFO, and its molecular weight is 158.56 g/mol.

  3. What is 4-Fluorobenzoyl Chloride used for?

    It is used in selected routes for fluorinated amide and ester preparation, aromatic ketone synthesis, pharmaceutical intermediate development, and laboratory research.

  4. Who supplies 4-Fluorobenzoyl Chloride in India?

    ChemicalBull supports 4-Fluorobenzoyl Chloride supply in India for chemical manufacturers, pharmaceutical intermediate developers, laboratories, distributors, and bulk buyers.

  5. Can I request bulk pricing and 4-Fluorobenzoyl Chloride MSDS?

    Yes. Share your quantity, specification, and delivery location with ChemicalBull to request bulk pricing and 4-Fluorobenzoyl Chloride CAS 403-43-0 MSDS or SDS. COA, TDS, and other documents can be requested for the offered grade.

ChemicalBull supplies 4-Fluorobenzoyl Chloride across India, serving customers in Andhra Pradesh, Arunachal Pradesh, Assam, Bihar, Chhattisgarh, Goa, Gujarat, Haryana, Himachal Pradesh, Jharkhand, Karnataka, Kerala, Madhya Pradesh, Maharashtra, Manipur, Meghalaya, Mizoram, Nagaland, Odisha, Punjab, Rajasthan, Sikkim, Tamil Nadu, Telangana, Tripura, Uttar Pradesh, Uttarakhand, and West Bengal, as well as the Union Territories of Andaman & Nicobar Islands, Chandigarh, Dadra & Nagar Haveli and Daman & Diu, Delhi, Jammu & Kashmir, Ladakh, Lakshadweep, and Puducherry. We serve pharmaceutical, chemical, research, academic, laboratory, manufacturing, and industrial customers with reliable nationwide delivery.