Triethylchlorosilane
Description :
Overview of Triethylchlorosilane
Triethylchlorosilane is an organosilicon compound used as a silylating agent, protecting group reagent, and chemical intermediate in organic synthesis. Known for its ability to form stable triethylsilyl (TES) protecting groups and for introducing silicon-containing functionalities, Triethylchlorosilane is widely used in pharmaceutical synthesis, materials chemistry, and the production of silicon-based compounds.
This compound appears as a colorless liquid with a characteristic pungent odor. Its chlorosilane structure provides reactivity with hydroxyl groups, while the triethyl groups provide useful steric and electronic properties.
Related products include Trimethylsilyl Trifluoromethanesulfonate, Trimethylchlorosilane, Pivalic Acid (used in similar protective applications), and other chlorosilanes used in organic synthesis.
Applications of Triethylchlorosilane
Pharmaceutical & Organic Synthesis
- Used in protecting hydroxyl groups (TES protection)
- Applied in carbohydrate chemistry
- Used in nucleoside and nucleotide synthesis
- Applied in preparing pharmaceutical intermediates
Industrial Silane Chemistry
- Used in producing organosilicon compounds
- Applied in the surface modification of materials
- Used in hydrophobic treatment applications
- Applied in manufacturing silicone polymers
Chemical Intermediate Production
- Used in preparing other silylating reagents
- Applied in the manufacturing of specialty chemicals
- Used in producing silicon-containing pharmaceuticals
- Applied in developing performance materials
Safety & Handling Guidelines
- HIGHLY REACTIVE—reacts with moisture, releasing HCl
- CORROSIVE and FLAMMABLE—handle with care
- Avoid inhalation of vapors and contact with skin/eyes
- Use in a well-ventilated fume hood
- Wear appropriate PPE, including gloves, goggles, and protective clothing
- Handle under anhydrous conditions
Where to Buy Triethylchlorosilane?
Triethylchlorosilane Manufacturer
ChemicalBull supplies high-purity Triethylchlorosilane for pharmaceutical and industrial applications.
Triethylchlorosilane Supplier & Distributor
- Available in bulk quantities for pharmaceutical and industrial use
- High-purity anhydrous grade (97%, 99%)
- Special moisture-resistant packaging
- COA, MSDS, and specifications provided
MSDS
Includes detailed reactivity warnings, corrosivity information, and handling protocols.
Frequently Asked Questions (FAQs)
-
What is Triethylchlorosilane used for?
Used as a silylating agent for protecting hydroxyl groups, in organosilicon compound synthesis, and surface modification applications. -
What is the molecular formula?
Molecular formula: C₆H₁₅ClSi with molecular weight 150.72 g/mol. -
How does TES protection differ from TMS protection?
TES groups (triethylsilyl) are more stable than TMS (trimethylsilyl); resistant to more conditions; removed under stronger conditions or with fluoride.
