Tranexamic Acid | 1197-18-8

Description :

Overview of Tranexamic Acid

Tranexamic Acid is an antifibrinolytic medication used to prevent and treat excessive bleeding during many surgical and medical ailments. It is renowned for its capacity to reduce fibrinolysis and stabilise blood clots. Tranexamic Acid is widely used for surgery, trauma, hemophilia, menorrhagia, or treatment.

This API appears as a white crystalline powder with good water solubility. Its mechanism—competitive inhibition of plasminogen activation and plasmin activity—prevents fibrin clot breakdown, thereby reducing bleeding in conditions with excessive fibrinolysis.

Related products include Aminocaproic Acid, Aprotinin, and other antifibrinolytic agents used in bleeding management.

Applications of Tranexamic Acid

Pharmaceutical API

• used in managing hemorrhage and trauma
• Used in the surgical bleeding prevention
• For the bleeding of menstrual cycles (menorrhagia)
• It is a treatment for hemophilia bleeding events
• Utilized for orthopedic and cardiac surgery procedures.
• Used for postpartum hemorrhage prevention

Formulation Development

• Used in tablets for oral administration
• Available in an injectable solution for IV use
• Topical formulations for wound bleeding
• Multiple strength options (500 mg, 650 mg tablets)
• Oral and parenteral routes are available
• Stable in both solid and liquid formulations

Hemostatic Treatment

• Lowers the loss of blood during surgical procedures (30-50 percent reduction)
• Reduces the need for transfusions
• Improves outcomes in trauma patients (CRASH-2 trial)
• Effective in menorrhagia management
• Reduces bleeding in hemophilia patients
• A safe and economical hemostatic agent

Safety & Handling Guidelines

• Do not inhale fine powder
• Make sure you wear gloves, goggles, or protective clothing while handling
• Keep it in a dry, cool space away from sunlight
• Use COA as well as MSDS directions strictly

Where to Buy Tranexamic Acid?

Tranexamic Acid Manufacturer

ChemicalBull supplies high-purity Tranexamic Acid API, meeting IP/EP/USP quality standards for pharmaceutical formulations.

Tranexamic Acid Supplier & Distributor

• Available in bulk packing for formulation units
• Stable and high-purity grade for research and production
• COA, MSDS, and regulatory documents provided

MSDS

Includes detailed safety instructions, hazard identification, and storage guidelines.

Frequently Asked Questions (FAQs)

1. What is Tranexamic Acid used for?
   

   Used for preventing/treating excessive bleeding in trauma, surgery, menorrhagia, dental procedures in hemophiliacs, and postpartum hemorrhage.
   
   

2. How does Tranexamic Acid work?
   

   Competitively inhibits plasminogen activation and plasmin, preventing fibrin clot breakdown and stabilizing formed clots, thereby reducing bleeding.
   
   

3. Is Tranexamic Acid safe?
   

   Generally safe when used appropriately; extensive safety data from trauma and surgical use; requires caution in patients with thrombotic risk.
   
   

4. What is the dosage for different indications?
   

   Trauma: 1g IV bolus then 1g over 8h; Menorrhagia: 1-1.5g orally 3-4x daily during menses; Surgery: varies by procedure.