Tetracaine Hydrochloride | 136-47-0
Cas No :
136-47-0
Form :
Solid
Molecular Weight :
300.82
Molecular Formula :
C15H24N2O2 · HCL
Melting Point :
135 - 138°C
Solubility :
Dichloromethane, Methanol
Description :
Overview of Tetracaine Hydrochloride
Tetracaine Hydrochloride is an effective ester-type local anesthetic that is used to provide spinal and topical anesthesia. It is renowned for its quick beginning, extended time of action, and its high potency. Tetracaine Hydrochloride is used extensively in dentistry, ophthalmology, techniques for spinal anesthesia, and the treatment of pain on the skin.
This API appears as a white to off-white crystalline powder with good water solubility and a bitter taste. Its mechanism—blocking sodium channels in neuronal membranes—prevents nerve impulse generation and conduction, providing effective local anesthesia for various medical and surgical procedures.
Related products include Lidocaine, Bupivacaine, Procaine, and other local anesthetic agents used in regional anesthesia and topical pain relief applications.
Applications of Tetracaine Hydrochloride
Pharmaceutical API
- Used in topical ophthalmic anesthesia (eye examinations, procedures)
- Applied in spinal anesthesia for surgical procedures
- Used for topical mucosal anesthesia
- Applied in diagnostic procedures requiring local anesthesia
- Used in combination with anesthetic formulations
- Applied in dental procedures and topical pain relief
Formulation Development
- Used in ophthalmic solutions and eye drops
- Available in injectable formulations for spinal anesthesia
- Applied in topical gels, creams, and ointments
- Used in lozenges for throat anesthesia
- Available in combination with other anesthetics
- Stable in properly formulated aqueous solutions
Medical & Surgical Applications
- Provides surface anesthesia for eye procedures
- Rapid onset (within 30 seconds for ophthalmic use)
- Long duration of action (30-60 minutes)
- Highly potent (10-15 times more potent than procaine)
- Suitable for various mucous membrane applications
- Used in emergency medicine and minor procedures
Safety & Handling Guidelines
- Potent local anesthetic—handle with care
- Avoid inhalation of fine powder
- Use gloves, goggles, and protective clothing during handling
- Store in a cool, dry place protected from light
- Follow COA and MSDS instructions strictly
Where to Buy Tetracaine Hydrochloride?
Tetracaine Hydrochloride Manufacturer
ChemicalBull supplies high-purity Tetracaine Hydrochloride API, meeting IP/EP/USP quality standards for pharmaceutical formulations.
Tetracaine Hydrochloride Supplier & Distributor
- Available in bulk packing for formulation units
- Stable and high-purity grade for research and production
- COA, MSDS, and regulatory documents provided
MSDS
Includes detailed safety instructions, hazard identification, and storage guidelines.
Frequently Asked Questions (FAQs)
-
What is the chemical formula of Tetracaine Hydrochloride?
The molecular formula is C₁₅H₂₄N₂O₂·HCl with a molecular weight of 300.83 g/mol. -
What is the structure of Tetracaine Hydrochloride?
Tetracaine is an ester local anesthetic with a para-aminobenzoic acid (PABA) ester structure, containing a butyl group and a dimethylaminoethyl side chain. -
What is the molecular weight of Tetracaine Hydrochloride?
The molecular weight is 300.83 g/mol (as hydrochloride salt). -
What is Tetracaine Hydrochloride used for?
It is used for topical ophthalmic anesthesia, spinal anesthesia, topical mucosal anesthesia, and various diagnostic and minor surgical procedures.