Niacin | 59-67-6

Description :

Overview of Niacin

Niacin (Nicotinic Acid/Vitamin B3) is a water-soluble vitamin, as well as a lipid-modifying drug used to treat dyslipidemia, niacin insufficiency, and pellagra. Niacin is renowned for its capacity to boost HDL cholesterol and decrease triglycerides and LDL cholesterol levels. It is extensively used for nutrition and cardiovascular health.

This API appears as a white to off-white crystalline powder with excellent stability under standard storage conditions. Its mechanism—inhibition of lipolysis in adipose tissue and modulation of lipid metabolism—provides comprehensive improvement of the lipid profile.

Related products include Fenofibrate, Atorvastatin, Gemfibrozil, and other lipid-lowering agents used in cardiovascular disease prevention and dyslipidemia management.

Applications of Niacin

Pharmaceutical API

• Used in lipid-modifying medications and vitamin supplements
• Effective in treating hyperlipidemia and mixed dyslipidemia
• Raises HDL cholesterol significantly
• Reduces triglycerides, LDL cholesterol, and lipoprotein(a)

Formulation Development

• Used in immediate-release, sustained-release, and extended-release tablets
• Suitable for combination formulations with statins
• Available in various dosage strengths
• Modified-release formulations reduce flushing side effects

Nutritional & Cardiovascular Treatment

• Prevents and treats niacin deficiency and pellagra
• Improves lipid profiles in cardiovascular disease prevention
• Supports energy metabolism and cellular function
• Used as adjunct therapy in comprehensive cardiovascular risk management

Safety & Handling Guidelines

• Avoid inhalation of fine powder
• Use gloves, goggles, and protective clothing during handling
• Store in a cool, dry place away from light and moisture
• Follow COA and MSDS instructions strictly

Where to Buy Niacin?

Niacin Manufacturer

ChemicalBull supplies high-purity Niacin (Nicotinic Acid) API, meeting IP/EP/USP quality standards for pharmaceutical and nutraceutical formulations.

Niacin Supplier & Distributor

• Available in bulk packing for formulation units
• Stable and high-purity grade for research and production
• COA, MSDS, and regulatory documents provided

MSDS

Includes detailed safety instructions, hazard identification, and storage guidelines.

Frequently Asked Questions (FAQs)

1. What is Niacin used for?
   

   It is used for treating high cholesterol, low HDL levels, high triglycerides, and niacin deficiency.
   
   

2. What is the difference between immediate-release and extended-release Niacin?
   

   Extended-release formulations reduce the flushing side effect common with immediate-release Niacin while maintaining lipid-modifying benefits.
   
   

3. Is Niacin stable for tablet formulation?
   

   Yes, it offers excellent stability in various solid dosage forms, including immediate and modified-release tablets.