Sodium Hexamethyl Disilazane Powder

Description :

Sodium Hexamethyl Disilazane Powder Supplier & Distributor In India

Chemical Bull is a Sodium Hexamethyl Disilazane Powder supplier, distributor, and exporter in India, supporting sourcing enquiries from pharmaceutical intermediate manufacturers, fine chemical companies, specialty synthesis units, research laboratories, distributors, wholesalers, and global B2B buyers.

Sodium Hexamethyl Disilazane Powder, CAS 1070-89-9, is commonly known as Sodium Hexamethyldisilazide, Sodium Bis(trimethylsilyl)amide, or NaHMDS. It is a strong, sterically hindered base used in organic synthesis and moisture-sensitive chemical processes.

Overview of Sodium Hexamethyl Disilazane Powder

Sodium Hexamethyldisilazide has the molecular formula C6H18NNaSi2 and a molecular weight of approximately 183.37 g/mol. Its condensed formula is NaN[Si(CH3)3]2.

NaHMDS is a sodium amide reagent with bulky trimethylsilyl groups. It is commonly selected for strong-base reactions where low nucleophilicity is useful, although reaction selectivity depends on the substrate, solvent, temperature, and process conditions.

Solid grades may be supplied as powder or chunks. Powder procurement should specify the required physical form. Solid NaHMDS differs from commercial solutions in THF, toluene, or other solvents, which require concentration and solvent specifications.

Buyers should review identity, active-base assay, assay method, residual solvent, impurity limits, physical form, packaging, and storage requirements. Moisture exposure can consume active reagent and affect process performance.

Applications of Sodium Hexamethyl Disilazane Powder

Deprotonation & Enolate Formation

NaHMDS is used to deprotonate suitable substrates and generate enolates in organic synthesis. Manufacturers should evaluate base strength, solvent compatibility, and selectivity against the established reaction conditions.

Pharmaceutical & Fine Chemical Intermediate Synthesis

Sodium Hexamethyldisilazide is used in selected multi-step synthesis routes requiring a strong, hindered base. Buyers should define analytical controls and process qualification requirements; reagent identity alone does not establish suitability for a pharmaceutical manufacturing process.

Carbene Generation & Specialty Transformations

The reagent is used in suitable carbene-generation reactions and selected specialty transformations, including reported sulfenamide amination chemistry. Suitability depends on the specific substrate and approved synthesis route.

Metal Complex Preparation & Research

NaHMDS is used in selected metal-complex preparation processes, including lanthanide complex chemistry. Research teams should confirm reagent assay and compatibility with the intended ligand and metal precursor.

Sodium Hexamethyl Disilazane Powder Price & Bulk Supply

Sodium Hexamethyl Disilazane Powder pricing depends on active-base assay, impurity limits, physical form, manufacturer, quantity, moisture-protective packaging, freight, and delivery destination.

Chemical Bull supports requests for product specifications, batch-specific COA, TDS, MSDS or SDS, packaging details, and export documentation for the offered grade.

For bulk and repeat procurement, share your monthly consumption, approved specification, required powder form, preferred packing, and delivery schedule. Minimum order quantity, availability, and lead time are confirmed during quotation.

Why Choose Chemical Bull For Sodium Hexamethyl Disilazane Powder?

Chemical Bull helps industrial procurement teams coordinate NaHMDS grade requirements, solid-versus-solution clarification, active-base assay details, technical documents, bulk pricing, and delivery arrangements.

Our team supports domestic and export enquiries for specialty synthesis reagents. Offered specifications, packaging, availability, and commercial terms are confirmed before order placement.

Sodium Hexamethyl Disilazane Powder MSDS & Handling

Sodium Hexamethyldisilazide is corrosive and reacts violently with water. It can cause severe skin burns and eye damage. Avoid moisture exposure, direct contact, and inhalation of dust. Follow the offered grade’s SDS for engineering controls and protective equipment.

Handle using suitable dry equipment and an inert atmosphere where specified. Keep containers tightly closed and follow the supplier’s temperature, moisture-exclusion, and storage requirements.

Review the grade-specific SDS before transfer, processing, spill response, disposal, or transportation. Powder and solvent-based solutions may have different handling and transport classifications.

Chemical Bull supports requests for Sodium Hexamethyl Disilazane Powder MSDS or SDS for the offered material.

Related Products

Explore related strong-base reagents for organic synthesis. These products differ in reactivity and handling requirements and are not direct substitutes without process evaluation.

• Sodium Tert-Butoxide
• Potassium Tert-Butoxide
• Sodium Hydride

Request a Quote for Sodium Hexamethyl Disilazane Powder

Send your required quantity, active-base assay, impurity limits, required powder form, application, packing requirements, and delivery destination.

Contact Chemical Bull for a Sodium Hexamethyl Disilazane Powder Bulk Quote to discuss specifications, availability, pricing, and technical documentation.

Frequently Asked Questions

1. What is Sodium Hexamethyl Disilazane Powder?

   It is the solid sodium reagent commonly called Sodium Hexamethyldisilazide, Sodium Bis(trimethylsilyl)amide, or NaHMDS. It is used as a strong, sterically hindered base in organic synthesis.

   
   

2. What is its CAS number and molecular formula?

   Its CAS number is 1070-89-9. The molecular formula is C6H18NNaSi2, and the molecular weight is approximately 183.37 g/mol.

   
   

3. Is NaHMDS powder the same as NaHMDS solution?

   Both contain the same active sodium reagent, but their supplied forms differ. Powder requires a solid-grade assay and physical-form specification, while solutions require concentration, solvent identity, and grade-specific handling information.

   
   

4. Is Sodium Hexamethyldisilazide moisture-sensitive?

   Yes. It reacts violently with water, and moisture exposure consumes active reagent. Follow the supplier’s SDS and specified dry-handling and storage requirements.

   
   

5. Where can I buy Sodium Hexamethyl Disilazane Powder in bulk in India?

   Chemical Bull supports supply enquiries in India and export markets. Share your assay requirement, physical form, quantity, packing, and destination to request bulk pricing, availability, COA, TDS, and MSDS or SDS.

ChemicalBull supplies Sodium Hexamethyl Disilazane Powder across India, serving customers in Andhra Pradesh, Arunachal Pradesh, Assam, Bihar, Chhattisgarh, Goa, Gujarat, Haryana, Himachal Pradesh, Jharkhand, Karnataka, Kerala, Madhya Pradesh, Maharashtra, Manipur, Meghalaya, Mizoram, Nagaland, Odisha, Punjab, Rajasthan, Sikkim, Tamil Nadu, Telangana, Tripura, Uttar Pradesh, Uttarakhand, and West Bengal, as well as the Union Territories of Andaman & Nicobar Islands, Chandigarh, Dadra & Nagar Haveli and Daman & Diu, Delhi, Jammu & Kashmir, Ladakh, Lakshadweep, and Puducherry. We serve pharmaceutical, chemical, research, academic, laboratory, manufacturing, and industrial customers with reliable nationwide delivery.