What is Sodium Hexamethyl Disilazane In THF 40%?

It is a solution of Sodium Hexamethyldisilazide, also called Sodium Bis(trimethylsilyl)amide or NaHMDS, in tetrahydrofuran. Confirm the 40% concentration basis and assay specification for the offered grade.

What is its CAS number?

The active reagent Sodium Hexamethyldisilazide has CAS number 1070-89-9. Its molecular formula is C6H18NNaSi2, and its molecular weight is approximately 183.38 g/mol.

What is Sodium Hexamethyl Disilazane In THF 40% used for?

It is used in carbonyl enolisation, phosphonium ylide preparation for Wittig reactions, selected amine synthesis, and base-mediated intermediate development.

Watch Video MSDS Specifications

Sodium Hexamethyl Disilazane In Thf 40%

Form :

Liquid

Molecular Weight :

183.39 g/mol

Boiling Point :

66 °C

Melting Point :

-108 °C

Flash Point :

-20 °C

Solubility :

Soluble in THF

Description :

Sodium Hexamethyl Disilazane In THF 40% Supplier & Distributor In India

ChemicalBull is a Sodium Hexamethyl Disilazane In THF 40% supplier, distributor, and exporter in India, supporting sourcing for pharmaceutical intermediate manufacturers, fine chemical companies, organic synthesis units, research laboratories, distributors, wholesalers, and global B2B buyers.

Sodium Hexamethyl Disilazane In THF 40% is more precisely known as Sodium Hexamethyldisilazide or Sodium Bis(trimethylsilyl)amide solution. The active compound, CAS 1070-89-9, is commonly abbreviated as NaHMDS. This strong base is supplied dissolved in tetrahydrofuran for selected organic synthesis applications.

Contact ChemicalBull for a Sodium Hexamethyl Disilazane In THF 40% Quote — Share your required quantity, concentration, packing requirements, and delivery location to request bulk pricing and supply details.

Overview of Sodium Hexamethyl Disilazane In THF 40%

Sodium Hexamethyldisilazide has the molecular formula C6H18NNaSi2 and a molecular weight of approximately 183.38 g/mol. These values describe the active reagent, while the commercial product is a solution containing THF.

The 40% grade is commercially described as a 40% by-weight solution in tetrahydrofuran. Confirm the concentration basis and assay tolerance during procurement. The solution is sensitive to air and moisture and requires suitable dry handling conditions.

Buyers should confirm active-base assay, solvent identity, appearance, density, impurity limits, packaging compatibility, and storage requirements. Match the concentration and grade to the intended synthesis route before bulk procurement.

Applications of Sodium Hexamethyl Disilazane In THF 40%

Carbonyl Enolisation

NaHMDS is used as a strong base for enolisation of suitable carbonyl compounds. The resulting enolates can participate in subsequent synthesis steps, depending on the substrate and reaction conditions.

Wittig Reagent Preparation

Sodium Hexamethyldisilazide can be used to generate phosphonium ylides for Wittig reactions. Reagent concentration and compatibility should be confirmed for the selected phosphonium salt and synthesis procedure.

Selected Amine Synthesis

NaHMDS can serve as a nitrogen source in selected aminomethylation processes and routes to primary amines from suitable alkyl halides. These applications require a validated procedure and controlled reaction conditions.

Fine Chemical & Intermediate Development

Synthesis teams use NaHMDS solutions in selected base-mediated intermediate preparation and laboratory process development. Evaluate active concentration, impurity specifications, and solvent compatibility before production scale-up.

Sodium Hexamethyl Disilazane In THF 40% Supply Support For Industrial Buyers

ChemicalBull supports sourcing enquiries from pharmaceutical intermediate producers, fine chemical manufacturers, organic synthesis laboratories, distributors, wholesalers, and export customers.

Buyers can request concentration details, analytical specifications, compatible packing options, COA, TDS, MSDS or SDS, and export documentation for the offered grade. Packaging and dispatch arrangements are confirmed according to quantity and destination.

Why Choose ChemicalBull For Sodium Hexamethyl Disilazane In THF 40%?

ChemicalBull helps B2B buyers discuss active-base concentration, bulk pricing, packaging requirements, and delivery arrangements for Sodium Hexamethyl Disilazane In THF 40%.

Our team supports technical document requests, domestic dispatch planning, export coordination, and repeat procurement enquiries. Availability, lead time, and commercial terms are confirmed during quotation.

Sodium Hexamethyl Disilazane In THF 40% MSDS & Handling

NaHMDS in THF is highly flammable, corrosive, and reacts violently with water. It can cause severe skin burns and eye damage. Handle using dry equipment, an appropriate inert atmosphere, and suitable ventilation. Keep away from moisture, ignition sources, and incompatible chemicals.

THF-containing solutions may form explosive peroxides. Follow the latest SDS and supplier instructions for storage temperature, shelf life, peroxide management, and container opening. Use compatible chemical-resistant gloves, goggles, a face shield, and protective clothing. Spills, disposal, and any quenching operation require an approved procedure performed by trained personnel.

Request a Quote for Sodium Hexamethyl Disilazane In THF 40%

Need Sodium Hexamethyl Disilazane In THF 40% for carbonyl enolisation, Wittig reagent preparation, selected amine synthesis, or fine chemical intermediate production?

Send your required quantity, concentration, assay requirements, impurity limits, packaging needs, application, and delivery location to ChemicalBull. Our team will discuss suitable specifications, availability, bulk pricing, and documentation for domestic or export orders.

Frequently Asked Questions

What is Sodium Hexamethyl Disilazane In THF 40%?
It is a solution of Sodium Hexamethyldisilazide, also called Sodium Bis(trimethylsilyl)amide or NaHMDS, in tetrahydrofuran. Confirm the 40% concentration basis and assay specification for the offered grade.
What is its CAS number?
The active reagent Sodium Hexamethyldisilazide has CAS number 1070-89-9. Its molecular formula is C6H18NNaSi2, and its molecular weight is approximately 183.38 g/mol.
What is Sodium Hexamethyl Disilazane In THF 40% used for?
It is used in carbonyl enolisation, phosphonium ylide preparation for Wittig reactions, selected amine synthesis, and base-mediated intermediate development.
Who supplies Sodium Hexamethyl Disilazane In THF 40% in India?
ChemicalBull supports supply enquiries in India for pharmaceutical intermediate manufacturers, fine chemical companies, synthesis laboratories, distributors, and bulk buyers.
Can I request bulk pricing and Sodium Hexamethyl Disilazane In THF 40% MSDS?
Yes. Contact ChemicalBull with your quantity, concentration, specification, packaging requirements, and delivery location to request bulk pricing and MSDS or SDS. COA, TDS, and other documentation can be requested for the offered grade.

ChemicalBull supplies Sodium Hexamethyl Disilazane In Thf 40% across India, serving customers in Andhra Pradesh, Arunachal Pradesh, Assam, Bihar, Chhattisgarh, Goa, Gujarat, Haryana, Himachal Pradesh, Jharkhand, Karnataka, Kerala, Madhya Pradesh, Maharashtra, Manipur, Meghalaya, Mizoram, Nagaland, Odisha, Punjab, Rajasthan, Sikkim, Tamil Nadu, Telangana, Tripura, Uttar Pradesh, Uttarakhand, and West Bengal, as well as the Union Territories of Andaman & Nicobar Islands, Chandigarh, Dadra & Nagar Haveli and Daman & Diu, Delhi, Jammu & Kashmir, Ladakh, Lakshadweep, and Puducherry. We serve pharmaceutical, chemical, research, academic, laboratory, manufacturing, and industrial customers with reliable nationwide delivery.