S-1-2-Chloroacetyl Pyrrolidine-2-Carbonitrile | 207557-35-5

Description :

(S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile Supplier

ChemicalBull is a reliable (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile supplier, distributor, trader and exporter in India for pharmaceutical intermediate manufacturing, Vildagliptin synthesis, custom synthesis and process-development requirements. Buyers comparing (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile manufacturers and suppliers can contact us for specifications, COA, MSDS/SDS, packing, availability and commercial pricing.

(S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile is a chiral chemical intermediate mainly used in the synthesis of Vildagliptin. Its CAS Number is 207557-35-5, molecular formula is C7H9ClN2O, and molecular weight is approximately 172.61 g/mol.

Overview of (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile

(S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile is a specialised chiral building block used in pharmaceutical synthesis. Its molecular structure contains a pyrrolidine ring, nitrile group and reactive chloroacetyl group.

The S-configuration is important because pharmaceutical manufacturing requires control over the stereochemical identity of the intermediate. Buyers should therefore evaluate both chemical purity and chiral purity before commercial use.

The product is mainly purchased by pharmaceutical intermediate manufacturers, API producers, contract manufacturing organisations, custom-synthesis companies and process-development laboratories.

It is an intermediate rather than a finished active pharmaceutical ingredient. Its use in regulated pharmaceutical production requires buyer approval, process validation and suitable quality documentation.

Applications of S-1-2-Chloroacetyl Pyrrolidine-2-Carbonitrile

Pharma Intermediate Production

The primary application of (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile is as an intermediate in the synthesis of Vildagliptin.

Its reactive chloroacetyl group supports further reaction with a suitable adamantane-based intermediate during the manufacturing route. The resulting process is used to build the required Vildagliptin structure.

Manufacturers should control chemical purity, chiral identity, related substances, residual solvents and unreacted starting materials. These parameters can affect reaction yield and the impurity profile of the downstream product.

Pharmaceutical Intermediate Manufacturing

Pharmaceutical intermediate companies use this material as a chiral building block in multi-stage organic synthesis.

Its suitability depends on the approved manufacturing route and the quality requirements of the next reaction stage. Buyers should confirm assay, specific rotation, moisture and process-related impurity limits before procurement.

Process Development and Research

Research and process-development teams use (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile to study Vildagliptin synthesis routes, reaction conditions, purification methods and impurity formation.

Research-grade and commercial manufacturing-grade products may differ in purity, packing, documentation and minimum order quantity. The required grade should be clearly stated when requesting a quotation.

Price and Commercial Supply

The (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile price depends on purity, chiral specification, impurity profile, order quantity, packing, manufacturing availability and destination.

For an accurate quotation, provide:

• Required assay and analytical method

• Required chiral purity or specific rotation

• Related-substance limits

• Residual-solvent requirements

• Trial, monthly or annual quantity

• Packing preference

• Delivery destination

Buyers searching for CAS 207557-35-5 price, Vildagliptin intermediate price or commercial supply can contact ChemicalBull for current availability and lead time.

Because this is a specialised pharmaceutical intermediate, buyers planning repeat procurement should share their forecast for sourcing and supply coordination.

Safety and Handling Guidelines

(S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile may be harmful if swallowed. It can cause skin and serious eye irritation, and its dust may irritate the respiratory system.

Handle the product in a properly ventilated area. Avoid breathing dust and prevent contact with the skin, eyes and clothing. Personnel should wear suitable gloves, protective clothing and eye or face protection.

Certain grades may require cool storage and protection from air, heat or moisture. Follow the storage conditions stated on the supplied label, specification and MSDS/SDS.

Where to Buy (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile

ChemicalBull supplies CAS 207557-35-5 for Vildagliptin intermediate manufacturing, pharmaceutical synthesis, custom synthesis and process-development requirements across India and selected international destinations.

(S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile Manufacturer

Buyers searching for an (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile manufacturer in India can contact ChemicalBull for suitable sourcing options based on purity, chiral requirements, quantity and application.

ChemicalBull coordinates sourcing, technical documentation, packing and delivery planning according to the buyer’s approved requirements.

Supplier and Distributor

As a B2B (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile supplier and distributor, ChemicalBull supports sample, trial, regular and commercial requirements.

Share your specification, required quantity, packing and destination to receive current availability, expected lead time and pricing.

MSDS for CAS 207557-35-5

The (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile MSDS/SDS provides information covering hazards, exposure controls, personal protection, handling, storage, first aid, accidental release and disposal.

Buyers may request the applicable MSDS/SDS, batch-specific COA and product specification before technical or commercial approval.

Request a Commercial Quotation

Looking for (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile for Vildagliptin or pharmaceutical intermediate production?

Share your required purity, chiral specification, impurity limits, quantity, packing and delivery destination with ChemicalBull.

Submit your requirement to receive suitable sourcing details, COA, MSDS/SDS, current availability and commercial pricing.

Frequently Asked Questions

1. What is the CAS number of (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile?

   The CAS Number is 207557-35-5. Its molecular formula is C7H9ClN2O, and its molecular weight is approximately 172.61 g/mol.
   
   

2. What is CAS 207557-35-5 mainly used for?

   It is mainly used as a chiral pharmaceutical intermediate in the synthesis of Vildagliptin.
   
   

3. Is this product a finished pharmaceutical ingredient?

   No. It is a chemical intermediate used during pharmaceutical synthesis. It should not be treated as a finished medicine or automatically considered an approved API.
   
   

4. Why is chiral purity important for this intermediate?

   The required Vildagliptin manufacturing route uses the S-configured intermediate. Incorrect stereochemistry or uncontrolled chiral impurities can affect downstream product quality.
   
   

5. How can buyers obtain the current price?

   The price depends on purity, chiral specification, impurity limits, quantity, packing and destination. Buyers should share their complete specification for an accurate quotation.

ChemicalBull supplies S-1-2-Chloroacetyl Pyrrolidine-2-Carbonitrile across India, serving customers in Andhra Pradesh, Arunachal Pradesh, Assam, Bihar, Chhattisgarh, Goa, Gujarat, Haryana, Himachal Pradesh, Jharkhand, Karnataka, Kerala, Madhya Pradesh, Maharashtra, Manipur, Meghalaya, Mizoram, Nagaland, Odisha, Punjab, Rajasthan, Sikkim, Tamil Nadu, Telangana, Tripura, Uttar Pradesh, Uttarakhand, and West Bengal, as well as the Union Territories of Andaman & Nicobar Islands, Chandigarh, Dadra & Nagar Haveli and Daman & Diu, Delhi, Jammu & Kashmir, Ladakh, Lakshadweep, and Puducherry. We serve pharmaceutical, chemical, research, academic, laboratory, manufacturing, and industrial customers with reliable nationwide delivery.