R-1-Phenylethylamine | 3886-69-9

Description :

Overview of R-1-Phenylethylamine

R-1-Phenylethylamine (R-(+)-a-Methylbenzylamine) is a chiral amine used as a resolving agent for chiral acids, a pharmaceutical intermediate, and a building block in asymmetric synthesis. It is renowned for its capability to create diastereomeric salts using racemic acids and allowing optical resolution. R-1-Phenylethylamine has been extensively used in the pharmaceutical manufacturing as well as chiral synthesis and as a precursor of numerous bioactive substances.

The chemical appears as a colorless or pale yellow liquid that has a distinctive smell of amine.

Its chiral center with (R)-configuration provides unique stereochemical properties essential for preparing enantiomerically pure pharmaceuticals.

Related products include S-1-Phenylethylamine, Phenylethylamine, and other chiral amines used in pharmaceutical synthesis and chiral resolution applications.

Applications of R-1-Phenylethylamine

Chiral Resolution

• Used as a resolving agent for racemic carboxylic acids
• Applied in separating enantiomers of pharmaceutical intermediates
• Used in the optical resolution of chiral acids
• Applied in preparing enantiomerically pure compounds

Pharmaceutical Synthesis

• Used as a chiral building block in drug synthesis
• Applied in preparing pharmaceutical intermediates
• Used in synthesizing CNS-active compounds
• Applied in the manufacturing of cardiovascular drugs

Research & Development

• Used in studying stereochemistry
• Applied in developing asymmetric catalysis

Safety & Handling Guidelines

• CORROSIVE and FLAMMABLE—handle with care
• Avoid inhalation of vapors
• Use gloves, goggles, and protective clothing
• Handle in a well-ventilated fume hood
• Store in tightly closed containers away from heat and ignition
• Keep away from strong acids and oxidizing agents
• Follow COA and MSDS instructions strictly

Where to Buy R-1-Phenylethylamine?

 R-1-Phenylethylamine Manufacturer

ChemicalBull supplies high-purity R-1-Phenylethylamine that meets pharmaceutical and research quality standards.

 R-1-Phenylethylamine Supplier & Distributor

• Available in bulk quantities for pharmaceutical and research use
• High-purity grades (98%, 99%, ≥99% ee)
• Enantiomeric excess certified batches
• COA, MSDS, and chiral analysis provided

MSDS

Includes detailed safety instructions, handling protocols, and storage guidelines.

Frequently Asked Questions (FAQs)

1. What is R-1-Phenylethylamine used for?
   

   Used as a chiral resolving agent for separating enantiomers, as a pharmaceutical intermediate, as a chiral building block in asymmetric synthesis, and in preparing enantiomerically pure compounds.
   
   

2. What is the molecular formula?
   

   Molecular formula: C₈H₁₁N with molecular weight 121.18 g/mol.
   
   

3. How does it function as resolving agent?
   

   Forms diastereomeric salts with racemic acids; diastereomers have different physical properties, enabling separation by crystallization or chromatography.