R-1-phenylethylamine | 3886-69-9

Cas No :

3886-69-9

Synonyms :

Form :

Liquid

Molecular Weight :

121.18 G/mol

Molecular Formula :

C8H11N

Boiling Point :

198 °c

Melting Point :

-5 °c

Flash Point :

90 °c

Solubility :

Soluble In Water; Soluble In Ethanol And Ether

Description :

Overview of R-1-Phenylethylamine

 

R-1-Phenylethylamine (R-(+)-a-Methylbenzylamine) is a chiral amine used as a resolving agent for chiral acids, a pharmaceutical intermediate, and a building block in asymmetric synthesis. It is renowned for its capability to create diastereomeric salts using racemic acids and allowing optical resolution. R-1-Phenylethylamine has been extensively used in the pharmaceutical manufacturing as well as chiral synthesis and as a precursor of numerous bioactive substances.

The chemical appears as a colorless or pale yellow liquid that has a distinctive smell of amine.

Its chiral center with (R)-configuration provides unique stereochemical properties essential for preparing enantiomerically pure pharmaceuticals.

Related products include S-1-Phenylethylamine, Phenylethylamine, and other chiral amines used in pharmaceutical synthesis and chiral resolution applications.

 

 

Applications of R-1-Phenylethylamine

 

Chiral Resolution

 

  • Used as a resolving agent for racemic carboxylic acids
  • Applied in separating enantiomers of pharmaceutical intermediates
  • Used in the optical resolution of chiral acids
  • Applied in preparing enantiomerically pure compounds

 

Pharmaceutical Synthesis

 

  • Used as a chiral building block in drug synthesis
  • Applied in preparing pharmaceutical intermediates
  • Used in synthesizing CNS-active compounds
  • Applied in the manufacturing of cardiovascular drugs

 

Research & Development

 

  • Used in studying stereochemistry
  • Applied in developing asymmetric catalysis

 

 

Safety & Handling Guidelines

 

  • CORROSIVE and FLAMMABLE—handle with care
  • Avoid inhalation of vapors
  • Use gloves, goggles, and protective clothing
  • Handle in a well-ventilated fume hood
  • Store in tightly closed containers away from heat and ignition
  • Keep away from strong acids and oxidizing agents
  • Follow COA and MSDS instructions strictly

 

 

Where to Buy R-1-Phenylethylamine?

 

 R-1-Phenylethylamine Manufacturer

 

ChemicalBull supplies high-purity R-1-Phenylethylamine that meets pharmaceutical and research quality standards.

 

 R-1-Phenylethylamine Supplier & Distributor

 

  • Available in bulk quantities for pharmaceutical and research use
  • High-purity grades (98%, 99%, ≥99% ee)
  • Enantiomeric excess certified batches
  • COA, MSDS, and chiral analysis provided

 

 

MSDS

 

Includes detailed safety instructions, handling protocols, and storage guidelines.

 

 

Frequently Asked Questions (FAQs)

 

  1. What is R-1-Phenylethylamine used for?

    Used as a chiral resolving agent for separating enantiomers, as a pharmaceutical intermediate, as a chiral building block in asymmetric synthesis, and in preparing enantiomerically pure compounds.

  2. What is the molecular formula?

    Molecular formula: C₈H₁₁N with molecular weight 121.18 g/mol.

  3. How does it function as resolving agent?

    Forms diastereomeric salts with racemic acids; diastereomers have different physical properties, enabling separation by crystallization or chromatography.

ChemicalBull supplies R-1-phenylethylamine across India, serving customers in Andhra Pradesh, Arunachal Pradesh, Assam, Bihar, Chhattisgarh, Goa, Gujarat, Haryana, Himachal Pradesh, Jharkhand, Karnataka, Kerala, Madhya Pradesh, Maharashtra, Manipur, Meghalaya, Mizoram, Nagaland, Odisha, Punjab, Rajasthan, Sikkim, Tamil Nadu, Telangana, Tripura, Uttar Pradesh, Uttarakhand, and West Bengal, as well as the Union Territories of Andaman & Nicobar Islands, Chandigarh, Dadra & Nagar Haveli and Daman & Diu, Delhi, Jammu & Kashmir, Ladakh, Lakshadweep, and Puducherry. We serve pharmaceutical, chemical, research, academic, laboratory, manufacturing, and industrial customers with reliable nationwide delivery.