Potassium Phthalimide | 1074-82-4
Cas No :
1074-82-4
Synonyms :
Form :
Solid
Molecular Weight :
185.22
Molecular Formula :
C8H4KNO2
Melting Point :
300 °C
Boiling Point :
366 °C
Solubility :
Soluble In Water
Flash Point :
174,6 °C
Description :
Overview of Potassium Phthalimide
Potassium Phthalimide is an important organic synthesis intermediate, primarily used in pharmaceutical, agrochemical, and fine chemical manufacturing. It is best known as the key reagent in the Gabriel Synthesis, where it is used to produce primary amines with high selectivity.
Chemically, it is the potassium salt of phthalimide, offering enhanced nucleophilicity compared to phthalimide itself. Because of its controlled reactivity, Potassium Phthalimide is widely used in laboratory-scale synthesis as well as industrial chemical production. Related products are Phthalimide, Phthalic Anhydride, Potassium Hydroxide (KOH), Hydrazine Hydrate, and Aniline.
Applications of Potassium Phthalimide
Pharmaceutical & API Manufacturing
Used as a core reagent in Gabriel synthesis to prepare primary amines.
Helps avoid secondary and tertiary amine formation.
Used in the synthesis of drug intermediates and speciality APIs.
Agrochemical Intermediates
Applied in the manufacture of herbicides, fungicides, and pesticide intermediates.
Allows precise nitrogen incorporation into agrochemical molecules.
Used by bulk agrochemical manufacturers.
Fine Chemical & Research Applications
Widely used in laboratory organic synthesis.
Preferred for reactions requiring clean amine formation.
Common in research institutions and speciality chemical labs.
Speciality Chemical Production
Used in advanced organic reactions involving alkyl halides.
Provides consistent reaction outcomes and scalability.
Safety & Handling Guidelines
- Avoid inhalation of dust and direct skin contact.
- Use gloves, goggles, and protective clothing during handling.
- Store in a dry, cool, and sealed container.
- Not intended for food, cosmetic, or fragrance applications.
- Always follow MSDS recommendations.
Where to Buy Potassium Phthalimide
Potassium Phthalimide Manufacturer
Produced by specialty chemical and pharmaceutical intermediate manufacturers.
Potassium Phthalimide Distributor & Supplier
ChemicalBull Pvt. Ltd. supplies Potassium Phthalimide to pharmaceutical, agrochemical, and research customers.
MSDS
Material Safety Data Sheet (MSDS) available upon request.
Frequently Asked Questions (FAQs)
-
What is Potassium Phthalimide used for?
It is mainly used in Gabriel synthesis for producing primary amines. -
Is Potassium Phthalimide used in perfumes or cosmetics?
No. It is strictly an industrial and laboratory chemical. -
How is Potassium Phthalimide different from Phthalimide?
It is more reactive due to the potassium salt form, making it suitable for nucleophilic substitution reactions. -
Is Potassium Phthalimide hazardous?
It should be handled with proper industrial safety measures as per MSDS. -
Which chemicals are commonly linked with Potassium Phthalimide?
Phthalimide, Phthalic Anhydride, Potassium Hydroxide, Hydrazine Hydrate, and Aniline.
