Phenyl Isothiocyanate
Description :
Overview of Phenyl Isothiocyanate
Phenyl Isothiocyanate (PITC) is an organic compound utilized in amino acid sequences as well as peptide chemistry and organic syntheses. The compound is well-known for its function in the Edman process for degradation of proteins and for its ability to interact with amines in order to create Thioureas. Phenyl Isothiocyanate is extensively used for biochemical research as well as pharmaceutical synthesis and as a derivatization agent in chemical analysis.
The compound is a transparent to light yellow colorless liquid that has a distinctive, unpleasant odor. The isothiocyanate functional group offers an excellent reaction with nucleophiles, especially amines. This makes it essential in the field of peptide science.
Similar products are Methyl Isothiocyanate, Allyl Isothiocyanate, Phenylboronic Acid, and many more isothiocyanates, as well as derivatization reagents utilized for analytical and biochemical applications.
Application for Phenyl Isothiocyanate
Peptide & Protein Chemistry
- It is used for Edman degradation to facilitate N-terminal sequencing
- It is used to identify amino acid sequences
- Utilized in peptide synthesis as well as modification
- Utilized in the analysis of protein structures
- It is used in the preparation of Phenylthiocarbamoyl (PTC) amino acids
- It is used in biochemical research
- It is used in studies on proteomics
- Applied in enzyme characterization
Analytical Chemistry
- It is used as a derivatization Reagent to make amino acids
- Utilized for HPLC evaluation of amino acids
- Utilized in the production of PTC-amino acid derivatives
- Used in separation techniques using chromatography
- It is used to quantify amino acids
- Used in the analysis of pharmaceuticals
- Utilized for food analysis based on chemistry
Organic Synthesis
- Utilized in the synthesis of the thiourea derivatives
- Utilized in the production of pharmaceutical intermediates
- It is used in the synthesis of heterocyclic compounds
- Applied in developing bioactive compounds
- It is used in the field of materials chemistry.
- Used in the synthesis of agrochemicals
Handling & Safety Guidelines
- HIGHLY TOXIC and LACHRYMATORY--extreme caution required
- Avoid skin contact, or ingestion of
- Utilize only within a fume hood that is well ventilated.
- Wear appropriate PPE, including gloves, goggles, and a lab coat
- Use small amounts in the proper container
- Storage in sealed, tightly sealed containers that are cool and dry, and shaded conditions
- Avoid contact with the elements of moisture, acids, and bases
- Take a shower in case of emergency, and eyewash on hand
- Be sure to follow COA and MSDS guidelines completely.
Where to Buy Phenyl Isothiocyanate?
Phenyl Isothiocyanate Manufacturer
ChemicalBull supplies high-purity Phenyl Isothiocyanate for research and analytical applications.
Phenyl Isothiocyanate Supplier & Distributor
- Available in controlled quantities for laboratory use
- High-purity grades (98%, 99%, sequencing grade)
- Special moisture-resistant packaging
- COA, MSDS, and safety documentation provided
MSDS
Includes comprehensive toxicity warnings, handling protocols, and emergency procedures.
Frequently Asked Questions (FAQs)
-
What is the structure of Phenyl Isothiocyanate?
Contains benzene ring directly attached to isothiocyanate group (-N=C=S); molecular formula C₇H₅NS. -
What are the uses of Phenyl Isothiocyanate?
Used in Edman degradation for protein sequencing, amino acid derivatization for analysis, peptide chemistry, and organic synthesis. -
What is Phenyl Isothiocyanate CAS No?
CAS number: 103-72-0.
