N-Propylmagnesium Chloride In Thf
Molecular Weight :
102.83 G/Mol
Boiling Point :
66 °C
Melting Point :
-108 °C
Flash Point :
-20 °C
Solubility :
Soluble In Thf And Diethyl Ether; Reactive With Water And Air
Description :
Overview of N-Propylmagnesium Chloride in THF
N-Propylmagnesium Chloride in THF (CAS: 7585-29-3) is a Grignard reagent that is widely used in organic synthesis for the formation of carbon-carbon bonds. This organomagnesium compound is typically dissolved in tetrahydrofuran (THF), a highly polar and aprotic solvent that stabilizes the reagent and enhances its reactivity. N-Propylmagnesium Chloride is essential in the synthesis of alcohols, ketones, and other complex organic molecules.
This reagent is utilized in nucleophilic substitution reactions, where it effectively adds the propyl group to various electrophilic compounds, leading to the formation of propylated products. It plays a crucial role in the synthesis of pharmaceuticals, fine chemicals, and specialty compounds. Due to its high reactivity, N-Propylmagnesium Chloride is used under controlled conditions and is highly valued in research and development in synthetic chemistry.
Related products available on ChemicalBull include Methylmagnesium Chloride in THF, Ethylmagnesium Bromide in THF, and Butylmagnesium Chloride in THF – used in a variety of organic synthesis applications.
Applications of N-Propylmagnesium Chloride in THF
Pharmaceutical Synthesis
-
Used in the formation of carbon-carbon bonds, crucial for pharmaceutical compound synthesis
-
Facilitates the propylation of various functional groups such as carbonyl compounds, epoxides, and esters
-
A key reagent in the preparation of pharmaceutical intermediates and active ingredients (APIs)
Fine Chemicals Manufacturing
-
Essential for the synthesis of fine chemicals and specialty compounds
-
Utilized in nucleophilic additions to form secondary alcohols, ketones, and esters
-
Plays a key role in the modification of organic molecules in the chemical industry
Organic Synthesis & Research
-
Widely used in academic and industrial research for nucleophilic substitution reactions
-
Plays a role in reaction studies related to organometallic chemistry
-
Useful in the development of complex organic compounds and functionalized molecules
Agrochemical Production
-
Applied in the synthesis of agrochemical intermediates
-
Contributes to the development of herbicides, pesticides, and other crop protection chemicals
-
Important in the chemical modification of agroactive molecules
Specialty Chemical Manufacturing
-
Used in the manufacture of specialty polymers, plasticizers, and resins
-
Plays a role in the synthesis of novel materials and custom chemical formulations
-
Enhances reaction efficiency and selectivity in fine chemical processes
Safety & Handling Guidelines
-
Handle with care, as N-Propylmagnesium Chloride is highly reactive and can react violently with water, moisture, and air
-
Wear protective gloves, goggles, and appropriate clothing when working with this reagent
-
Store in tightly sealed containers in an inert atmosphere (such as nitrogen or argon) to avoid contact with moisture
-
Use under anhydrous conditions and ensure proper ventilation when handling in lab settings
-
Follow COA and MSDS instructions carefully for handling, storage, and disposal
Where to Buy N-Propylmagnesium Chloride in THF?
N-Propylmagnesium Chloride in THF Manufacturer
ChemicalBull supplies high-purity N-Propylmagnesium Chloride in THF suitable for organic synthesis, pharmaceutical production, and chemical research.
N-Propylmagnesium Chloride in THF Supplier & Distributor
-
Available in bulk and laboratory-scale packaging
-
Ideal for nucleophilic substitution reactions and pharmaceutical synthesis
-
COA, MSDS, and technical specifications provided
Light Diesel Oil MSDS
-
Highly reactive and can react violently with water and moisture
-
May cause burns to skin, eyes, and respiratory tract upon contact
-
Store in dry, inert conditions away from moisture and oxidizing agents
-
Follow MSDS for spill control, first aid measures, and emergency procedures
Frequently Asked Questions (FAQs)
-
What is the molecular formula of N-Propylmagnesium Chloride in THF?
Molecular Formula: C₃H₇MgCl
Molecular Weight: 92.84 g/mol -
What is N-Propylmagnesium Chloride in THF used for?
It is primarily used in organic synthesis for carbon-carbon bond formation, especially in pharmaceutical, fine chemical, and specialty compound synthesis. -
Is N-Propylmagnesium Chloride in THF hazardous?
Yes, it is highly reactive and can cause burns upon contact with skin and eyes. Proper PPE and handling precautions should be followed. -
How should N-Propylmagnesium Chloride in THF be stored?
It should be stored in tightly sealed containers under anhydrous conditions in a cool, dry place. Keep away from moisture and water. -
Which industries use N-Propylmagnesium Chloride in THF?
It is used in pharmaceutical, agrochemical, and chemical manufacturing industries for organic synthesis and fine chemical production.