P-Toluidine | 106-49-0

Description :

Overview of P-Toluidine

P-Toluidine (4-Methylaniline) is an aromatic amine that is used to make a pharmaceutical as well as a dye intermediate in chemical manufacturing. The name is due to its para-substituted methyl group, which offers an uncontrolled reactivity as well as distinctive electronic properties. P-Toluidine is used extensively for the production of dyes, pharmaceuticals, and rubber chemicals. It is also used as a multi-functional chemical building block for organic chemical synthesis.

This chemical appears as an uncolored to light yellow liquid, or as a crystalline solid which may change color upon exposure to light and air. The electron-donating methyl group stimulates the aromatic ring, while creating electronic and steric effects that can be useful in the synthesis of specific molecules.

The products that are related include P-Anisidine, O-Toluidine, Aniline, and various substituted anilines that are used in industrial and pharmaceutical chemicals.

Application of P-Toluidine

Pharmaceutical Synthesis

• Utilized in the production of pharmaceutical intermediates
• It is used in the manufacture of pharmaceutical substances
• Utilized in the creation of antimalarial drugs
• Applied in developing antibiotics
• Utilized in the synthesis of cardiovascular medications
• Used in the preparation of analgesic chemicals
• It is used in pharmaceutical API production
• Used to research medicinal chemistry

Dye & Chemical Manufacturing

• It is used in the production of pigments and azo dyes
• It is used to create dyes for textiles
• Utilized in the process of synthesizing dye intermediates
• Applied in developing colorants
• used in the preparation of special chemicals
• Used in chemical manufacturing
• used in the manufacture of antioxidants
• It is used in the manufacture of polymer additives

Organic Synthesis

• It is used in the Buchwald-Hartwig Amination
• It is used in Ullmann's coupling reactions
• It is used in the preparation of toluidine derivatives
• Used in the process of synthesizing heterocyclic compounds
• Utilized in the development of practical materials
• Used in the fine chemical synthesis

Safety & Handling Guidelines

• TOXIC and CARCINOGENIC—handle with extreme caution
• Methemoglobin former—avoid all exposure routes
• Use gloves, goggles, and protective clothing
• Handle in a well-ventilated fume hood
• Store in tightly closed containers protected from light and air
• Keep in a cool, dark place
• Dispose of according to hazardous waste regulations
• Follow COA and MSDS instructions strictly

Where to Buy P-Toluidine?

P-Toluidine Manufacturer

ChemicalBull supplies high-purity P-Toluidine for authorized pharmaceutical and industrial applications with strict regulatory compliance.

P-Toluidine Supplier & Distributor

• Available in controlled quantities for authorized use
• High-purity grades (98%, 99%)
• Requires appropriate safety documentation
• COA, MSDS, and regulatory information provided

MSDS

Includes comprehensive toxicity warnings, carcinogenicity information, and strict handling protocols.

Frequently Asked Questions (FAQs)

1. What is the P-Toluidine structure?
   

   Benzene ring with an amino group (-NH₂) and a methyl group (-CH₃) in para positions; molecular formula C₇H₉N.
   
   

2. What is P-Toluidine colour?
   

   Colorless to pale yellow liquid or white to pale pink crystals; darkens on exposure to air and light.
   
   

3. What is P-Toluidine melting point?
   

   Melting point approximately 43-45°C.
   
   

4. What is P-Toluidine molecular weight?
   

   Molecular weight: 107.15 g/mol.
   
   

5. What is P-Toluidine chemical formula?
   

   Molecular formula: C₇H₉N or CH₃C₆H₄NH₂.