P-toluidine | 106-49-0

Cas No :

106-49-0

Synonyms :

Form :

Liquid

Molecular Weight :

107.16 G/mol

Molecular Formula :

C7H9N

Boiling Point :

210 °c

Melting Point :

-5 °c

Flash Point :

85 °c

Solubility :

Soluble In Water; Soluble In Organic Solvents

Description :

Overview of P-Toluidine

 

P-Toluidine (4-Methylaniline) is an aromatic amine that is used to make a pharmaceutical as well as a dye intermediate in chemical manufacturing. The name is due to its para-substituted methyl group, which offers an uncontrolled reactivity as well as distinctive electronic properties. P-Toluidine is used extensively for the production of dyes, pharmaceuticals, and rubber chemicals. It is also used as a multi-functional chemical building block for organic chemical synthesis.

This chemical appears as an uncolored to light yellow liquid, or as a crystalline solid which may change color upon exposure to light and air. The electron-donating methyl group stimulates the aromatic ring, while creating electronic and steric effects that can be useful in the synthesis of specific molecules.

The products that are related include P-Anisidine, O-Toluidine, Aniline, and various substituted anilines that are used in industrial and pharmaceutical chemicals.

 

 

Application of P-Toluidine

 

Pharmaceutical Synthesis

 

  • Utilized in the production of pharmaceutical intermediates
  • It is used in the manufacture of pharmaceutical substances
  • Utilized in the creation of antimalarial drugs
  • Applied in developing antibiotics
  • Utilized in the synthesis of cardiovascular medications
  • Used in the preparation of analgesic chemicals
  • It is used in pharmaceutical API production
  • Used to research medicinal chemistry

 

Dye & Chemical Manufacturing

 

  • It is used in the production of pigments and azo dyes
  • It is used to create dyes for textiles
  • Utilized in the process of synthesizing dye intermediates
  • Applied in developing colorants
  • used in the preparation of special chemicals
  • Used in chemical manufacturing
  • used in the manufacture of antioxidants
  • It is used in the manufacture of polymer additives

 

Organic Synthesis

 

  • It is used in the Buchwald-Hartwig Amination
  • It is used in Ullmann's coupling reactions
  • It is used in the preparation of toluidine derivatives
  • Used in the process of synthesizing heterocyclic compounds
  • Utilized in the development of practical materials
  • Used in the fine chemical synthesis

 

 

Safety & Handling Guidelines

 

  • TOXIC and CARCINOGENIC—handle with extreme caution
  • Methemoglobin former—avoid all exposure routes
  • Use gloves, goggles, and protective clothing
  • Handle in a well-ventilated fume hood
  • Store in tightly closed containers protected from light and air
  • Keep in a cool, dark place
  • Dispose of according to hazardous waste regulations
  • Follow COA and MSDS instructions strictly

 

 

Where to Buy P-Toluidine?

 

P-Toluidine Manufacturer

 

ChemicalBull supplies high-purity P-Toluidine for authorized pharmaceutical and industrial applications with strict regulatory compliance.

 

P-Toluidine Supplier & Distributor

 

  • Available in controlled quantities for authorized use
  • High-purity grades (98%, 99%)
  • Requires appropriate safety documentation
  • COA, MSDS, and regulatory information provided

 

 

MSDS

 

Includes comprehensive toxicity warnings, carcinogenicity information, and strict handling protocols.

 

 

Frequently Asked Questions (FAQs)

 

  1. What is the P-Toluidine structure?

    Benzene ring with an amino group (-NH₂) and a methyl group (-CH₃) in para positions; molecular formula C₇H₉N.

  2. What is P-Toluidine colour?

    Colorless to pale yellow liquid or white to pale pink crystals; darkens on exposure to air and light.

  3. What is P-Toluidine melting point?

    Melting point approximately 43-45°C.

  4. What is P-Toluidine molecular weight?

    Molecular weight: 107.15 g/mol.

  5. What is P-Toluidine chemical formula?

    Molecular formula: C₇H₉N or CH₃C₆H₄NH₂.

ChemicalBull supplies P-toluidine across India, serving customers in Andhra Pradesh, Arunachal Pradesh, Assam, Bihar, Chhattisgarh, Goa, Gujarat, Haryana, Himachal Pradesh, Jharkhand, Karnataka, Kerala, Madhya Pradesh, Maharashtra, Manipur, Meghalaya, Mizoram, Nagaland, Odisha, Punjab, Rajasthan, Sikkim, Tamil Nadu, Telangana, Tripura, Uttar Pradesh, Uttarakhand, and West Bengal, as well as the Union Territories of Andaman & Nicobar Islands, Chandigarh, Dadra & Nagar Haveli and Daman & Diu, Delhi, Jammu & Kashmir, Ladakh, Lakshadweep, and Puducherry. We serve pharmaceutical, chemical, research, academic, laboratory, manufacturing, and industrial customers with reliable nationwide delivery.