P-Anisidine | 104-94-9

Cas No :

104-94-9

Form :

Solid

Molecular Weight :

 123.16 

Molecular Formula :

C7H9NO

Boiling Point :

240 - 243 °C

Melting Point :

56 - 59 °C

Flash Point :

122 °C

Solubility :

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

Description :

Overview of P-Anisidine

 

P-Anisidine (4-Methoxyaniline) is an aromatic amine that is used for its role as a pharmaceutical intermediary as well as a dye intermediate for organic chemical synthesis. It is renowned for its para-substituted methoxy group, which has unique electronic properties as well as reactivity. P-Anisidine can be found in the manufacturing of dyes, pharmaceuticals, and pigments. It is also used as a component in fine chemical synthesis.

This substance appears as a reddish to white crystalline solid, which darkens upon exposure to light and air. The electron-donating methoxy groups in it activate the aniline ring to induce electrophilic exchange while generating a distinctive pattern of reactivity.

Similar products are P-Toluidine, Aniline, O-Anisidine, as well as other anilines substituted in the synthesis of dyes and pharmaceuticals. It can be utilized in conjunction with other reagents, such as Diethyl Maleate and Diethyl Oxalate, to create a multi-step synthesis of pharmaceuticals.

 

 

Applications of P-Anisidine

 

Pharmaceutical Synthesis

 

  • Utilized in the production of pharmaceutical intermediates
  • It is used in the process of preparing drug substances
  • Utilized in the production of antimalarial drugs
  • Applied in developing antibacterial agents
  • Utilized in the synthesis of antihypertensive medications
  • It is used in the process of preparing analgesic substances
  • Utilized in the development of APIs for pharmaceuticals.
  • Used to research medicinal chemistry

 

Dye & Pigment Manufacturing

 

  • It is used in the production of Azo dyes
  • Applied in producing disperse dyes
  • Utilized in the production of dyes for textiles
  • Used in the process of synthesizing pigments
  • Used in developing colorants
  • Used in special dye manufacturing

 

Organic Synthesis

 

  • used in the Buchwald-Hartwig coupling reaction
  • Used in the preparation of anisidine derivatives
  • It is used to synthesize heterocyclic compounds
  • Applied in developing functional materials
  • Utilized in the production of polymer intermediates
  • Used for fine chemical production

 

 

Safety & Handling Guidelines

 

  • TOXIC and suspected carcinogen—handle with caution
  • Avoid inhalation of dust and vapors
  • Use gloves, goggles, and protective clothing
  • Handle in a well-ventilated fume hood
  • Oxidizes in air—protect from light and air exposure
  • Store in tightly closed containers in a cool, dark place
  • Dispose of according to hazardous waste regulations
  • Follow COA and MSDS instructions strictly

 

 

Where to Buy P-Anisidine?

 

P-Anisidine Manufacturer

 

ChemicalBull supplies high-purity P-Anisidine that meets pharmaceutical and industrial quality standards.

 

P-Anisidine Supplier & Distributor

 

  • Available in bulk quantities for pharmaceutical and industrial use
  • High-purity grades (98%, 99%)
  • Technical and pharmaceutical grades
  • COA, MSDS, and specifications provided

 

 

MSDS

 

Includes detailed toxicity information, safety instructions, and handling protocols.

 

 

Frequently Asked Questions (FAQs)

 

  1. What is the P-Anisidine melting point?

    Melting point approximately 57-59°C.

  2. What is P-Anisidine CAS No?

    CAS number: 104-94-9.

  3. What is the molecular weight of P-Anisidine?

    Molecular weight: 123.15 g/mol.

  4. What is the P-Anisidine formula?

    Molecular formula: C₇H₉NO or CH₃OC₆H₄NH₂.

  5. What is P-Anisidine's other name?

    Also known as 4-methoxyaniline, para-anisidine, or 4-aminoanisole.