P-Anisidine | 104-94-9
Cas No :
104-94-9
Form :
Solid
Molecular Weight :
123.16
Molecular Formula :
C7H9NO
Boiling Point :
240 - 243 °C
Melting Point :
56 - 59 °C
Flash Point :
122 °C
Solubility :
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Description :
Overview of P-Anisidine
P-Anisidine (4-Methoxyaniline) is an aromatic amine that is used for its role as a pharmaceutical intermediary as well as a dye intermediate for organic chemical synthesis. It is renowned for its para-substituted methoxy group, which has unique electronic properties as well as reactivity. P-Anisidine can be found in the manufacturing of dyes, pharmaceuticals, and pigments. It is also used as a component in fine chemical synthesis.
This substance appears as a reddish to white crystalline solid, which darkens upon exposure to light and air. The electron-donating methoxy groups in it activate the aniline ring to induce electrophilic exchange while generating a distinctive pattern of reactivity.
Similar products are P-Toluidine, Aniline, O-Anisidine, as well as other anilines substituted in the synthesis of dyes and pharmaceuticals. It can be utilized in conjunction with other reagents, such as Diethyl Maleate and Diethyl Oxalate, to create a multi-step synthesis of pharmaceuticals.
Applications of P-Anisidine
Pharmaceutical Synthesis
- Utilized in the production of pharmaceutical intermediates
- It is used in the process of preparing drug substances
- Utilized in the production of antimalarial drugs
- Applied in developing antibacterial agents
- Utilized in the synthesis of antihypertensive medications
- It is used in the process of preparing analgesic substances
- Utilized in the development of APIs for pharmaceuticals.
- Used to research medicinal chemistry
Dye & Pigment Manufacturing
- It is used in the production of Azo dyes
- Applied in producing disperse dyes
- Utilized in the production of dyes for textiles
- Used in the process of synthesizing pigments
- Used in developing colorants
- Used in special dye manufacturing
Organic Synthesis
- used in the Buchwald-Hartwig coupling reaction
- Used in the preparation of anisidine derivatives
- It is used to synthesize heterocyclic compounds
- Applied in developing functional materials
- Utilized in the production of polymer intermediates
- Used for fine chemical production
Safety & Handling Guidelines
- TOXIC and suspected carcinogen—handle with caution
- Avoid inhalation of dust and vapors
- Use gloves, goggles, and protective clothing
- Handle in a well-ventilated fume hood
- Oxidizes in air—protect from light and air exposure
- Store in tightly closed containers in a cool, dark place
- Dispose of according to hazardous waste regulations
- Follow COA and MSDS instructions strictly
Where to Buy P-Anisidine?
P-Anisidine Manufacturer
ChemicalBull supplies high-purity P-Anisidine that meets pharmaceutical and industrial quality standards.
P-Anisidine Supplier & Distributor
- Available in bulk quantities for pharmaceutical and industrial use
- High-purity grades (98%, 99%)
- Technical and pharmaceutical grades
- COA, MSDS, and specifications provided
MSDS
Includes detailed toxicity information, safety instructions, and handling protocols.
Frequently Asked Questions (FAQs)
-
What is the P-Anisidine melting point?
Melting point approximately 57-59°C. -
What is P-Anisidine CAS No?
CAS number: 104-94-9. -
What is the molecular weight of P-Anisidine?
Molecular weight: 123.15 g/mol. -
What is the P-Anisidine formula?
Molecular formula: C₇H₉NO or CH₃OC₆H₄NH₂. -
What is P-Anisidine's other name?
Also known as 4-methoxyaniline, para-anisidine, or 4-aminoanisole.