Nalidixic Acid | 389-08-2

Description :

Overview of Nalidixic Acid

Nalidixic Acid can be described as a primary-generation anti-quinolone medication used to treat UTIs that are caused by gram-negative bacteria. It is renowned for its bactericidal properties against susceptible organisms. Nalidixic Acid is extensively utilized in antibacterial formulations for treating uncomplicated UTIs.

This API appears as a pale yellow to yellow crystalline powder and is stable under controlled storage conditions. Its mechanism—inhibition of bacterial DNA gyrase—prevents DNA replication and bacterial growth, making it effective against common urinary pathogens.

Related products include Ciprofloxacin, Norfloxacin, Nitrofurantoin, and other quinolone antibiotics used in urinary and systemic antibacterial therapy.

Applications of Nalidixic Acid

Pharmaceutical API

• Used in antibacterial medications for urinary tract infections
• Effective against gram-negative bacteria, including E. coli, Proteus, and Klebsiella
• Bactericidal action through DNA gyrase inhibition
• Used mainly for uncomplicated lower UTIs

Formulation Development

• Used in tablets, capsules, and oral suspensions
• Suitable for short-term antibacterial therapy
• Offers good oral bioavailability
• Stable in solid and liquid dosage forms

Urinary Antibacterial Treatment

• Helps treat acute and recurrent urinary tract infections
• Concentrated in urine, providing targeted antibacterial action
• Used when broader-spectrum antibiotics are not required
• Suitable for pediatric and adult populations

Safety & Handling Guidelines

• Avoid inhalation of fine powder
• Use gloves, goggles, and protective clothing during handling
• Store in a cool, dry place away from light
• Follow COA and MSDS instructions strictly

Where to Buy Nalidixic Acid?

Nalidixic Acid Manufacturer

ChemicalBull supplies high-purity Nalidixic Acid API that meets IP/EP/USP quality standards for pharmaceutical formulations.

Nalidixic Acid Supplier & Distributor

• Available in bulk packing for formulation units
• Stable and high-purity grade for research and production
• COA, MSDS, and regulatory documents provided

MSDS

Includes detailed safety instructions, hazard identification, and storage guidelines.

Frequently Asked Questions (FAQs)

1. What is Nalidixic Acid used for?
   

   It is used for treating uncomplicated urinary tract infections caused by susceptible gram-negative bacteria.
   
   

2. Is Nalidixic Acid a broad-spectrum antibiotic?
   

   No, it is a narrow-spectrum quinolone primarily effective against gram-negative bacteria in the urinary tract.
   
   

3. Is Nalidixic Acid stable for oral formulations?
   

   Yes, it is stable in both solid and liquid oral dosage forms.