N-Hydroxy Succinimide | 6066-82-6
Cas No :
6066-82-6
Form :
Powder
Molecular Weight :
115.09 G/Mol
Molecular Formula :
C4H5NO3
Boiling Point :
260 °C
Melting Point :
125 °C
Flash Point :
125 °C
Solubility :
Soluble In Water; Soluble In Acetone And Methanol
Description :
Overview of N-Hydroxy Succinimide
N-Hydroxy Succinimide (NHS) is a widely used organic compound in pharmaceutical synthesis, peptide chemistry, and bioconjugation reactions. It is primarily employed to activate carboxylic acids for the formation of stable amide bonds, making it essential in peptide coupling and drug intermediate manufacturing.
N-Hydroxy Succinimide appears as a white to off-white crystalline powder with good chemical stability under dry conditions. It is soluble in polar organic solvents and moderately soluble in water. Due to its ability to form NHS esters, it plays a critical role in improving reaction efficiency and reducing side-product formation in pharmaceutical and biochemical synthesis.
ChemicalBull supplies pharma and industrial-grade N-Hydroxy Succinimide with controlled purity, consistent reactivity, and reliable batch-to-batch performance suitable for regulated manufacturing and research environments. Each shipment is supported with complete documentation, including MSDS, COA, and technical data sheets.
As a trusted chemical supplier and reliable distributor, ChemicalBull ensures dependable availability of N-Hydroxy Succinimide. You may also like N,N-Diisopropylcarbodiimide (DIC), EDC Hydrochloride, DCC, and Pharmaceutical Intermediates for related peptide synthesis and coupling reagent applications.
Applications of N-Hydroxy Succinimide
Pharmaceutical Intermediates
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Used in amide bond formation reactions
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Applied in API and drug intermediate synthesis
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Supports ester activation processes
Peptide & Bioconjugation Chemistry
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Used in the preparation of NHS esters
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Applied in protein labelling and conjugation
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Enhances coupling reaction efficiency
Research & Development
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Used in medicinal and organic chemistry research
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Applied in reaction optimisation and process studies
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Suitable for laboratory and pilot-scale production
Fine Chemical Manufacturing
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Used in speciality organic synthesis
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Applied in contract manufacturing projects
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Ensures controlled and reproducible reaction performance
Safety & Handling Guidelines
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Handle using gloves and appropriate protective equipment
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Avoid inhalation of dust
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Use in a well-ventilated laboratory or processing areas
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Store in tightly sealed containers away from moisture
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Follow MSDS and standard chemical safety practices
Where to Buy N-Hydroxy Succinimide?
N-Hydroxy Succinimide Manufacturer
ChemicalBull supplies pharma and industrial-grade N-Hydroxy Succinimide suitable for peptide synthesis and pharmaceutical intermediate manufacturing.
N-Hydroxy Succinimide Supplier & Distributor
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Bulk and customised packaging options
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Export-grade quality with COA, TDS & MSDS
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Reliable supply across India and international markets
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Trusted chemical supplier for pharmaceutical intermediates and coupling reagents
N-Hydroxy Succinimide MSDS
The N-Hydroxy Succinimide MSDS provides essential information on safe handling, storage conditions, exposure controls, chemical stability, and emergency procedures. Always review the MSDS before bulk handling or industrial use.
Frequently Asked Questions (FAQs)
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Why is N-Hydroxy Succinimide used in peptide synthesis?
It helps form activated esters that improve amide bond formation efficiency. -
What are NHS esters?
They are activated intermediates formed from NHS that facilitate coupling reactions. -
Is N-Hydroxy Succinimide supplied as a solid?
Yes, it is typically supplied as a crystalline powder. -
Can N-Hydroxy Succinimide be used in bioconjugation reactions?
Yes, it is widely used for protein and biomolecule labelling. -
Is safety documentation provided with the supply?
Yes, every shipment includes MSDS, COA, and complete technical documentation.