Methylmagnesium Bromide

Description :

Overview of Methylmagnesium Bromide

Methylmagnesium Bromide is a Grignard reagent used extensively in organic synthesis for carbon-carbon bond formation, pharmaceutical manufacturing, and chemical research.

Known for its powerful nucleophilic properties and ability to add methyl groups to electrophiles, Methylmagnesium Bromide is widely used in pharmaceutical synthesis, fine chemical production, and the development of complex organic molecules.

This compound appears as a solution in ether solvents (typically THF or diethyl ether) with characteristic concentration ranges. Its organometallic structure provides excellent reactivity for forming new carbon-carbon bonds through addition to carbonyl compounds and other electrophiles.

Related products include Ethylmagnesium Bromide, Phenylmagnesium Bromide, Lithium Bis(Trimethylsilyl)Amide, and other Grignard reagents used in organic synthesis and pharmaceutical chemistry.

Applications of Methylmagnesium Bromide

Pharmaceutical Synthesis

• It is used to synthesize pharmaceutical intermediates
• Applied in forming carbon-carbon bonds in drug molecules
• Utilized in the production of Tertiary alcohols
• It is used in the manufacture of active pharmaceutical components

Industrial Organic Synthesis

• It is used in the preparation of organic magnesium compounds
• Used in nucleophilic addition reactions
• It is used to synthesize complex organic molecules in the synthesis of complex organic molecules.

Research & Development

• Used in academic research laboratories
• Applied in studying organometallic chemistry
• Used in developing synthetic methodologies
• Applied in chemical biology investigations

Safety & Handling Guidelines

• HIGHLY REACTIVE and PYROPHORIC—handle with extreme care
• Reacts violently with water, oxygen, and protic solvents
• Use only under strictly anhydrous conditions and an inert atmosphere
• Handle in the glove box or using Schlenk techniques
• Wear full PPE, including chemical-resistant gloves, face shield
• Store in tightly sealed containers under argon or nitrogen

Where to Buy Methylmagnesium Bromide?

Methylmagnesium Bromide Manufacturer

ChemicalBull supplies high-purity Methylmagnesium Bromide solutions for pharmaceutical and research applications.

Methylmagnesium Bromide Supplier & Distributor

• Available in various concentrations in THF or diethyl ether
• Multiple concentration options (1M, 3M in ether solvents)
• High-purity grades for pharmaceutical synthesis
• Packaged under an inert atmosphere with appropriate safety features
• COA, MSDS, and comprehensive safety documentation provided

MSDS

Includes comprehensive pyrophoric material handling instructions, reactivity warnings, and emergency procedures.

Frequently Asked Questions (FAQs)

1. What is Methylmagnesium Bromide used for?
   

   Used as a Grignard reagent for carbon-carbon bond formation, methylation reactions, pharmaceutical intermediate synthesis, and preparing tertiary alcohols.
   
   

2. What is the molecular formula?
   

   Molecular formula: CH₃MgBr with molecular weight 119.24 g/mol.
   
   

3. How reactive is Methylmagnesium Bromide?
   

   Extremely reactive; reacts violently with water, oxygen, and protic compounds; must be handled under strictly anhydrous, inert atmosphere conditions.