Lithium Diisopropylamide | 4111-54-0

Description :

Overview of Lithium Diisopropylamide

Lithium Diisopropylamide (commonly called LDA) is highly reacting chemical organolithium used for industrial use that is typically found in an solution within hydrocarbon solvents that are inert conditions. It is highly valued due to its solid base characteristics, which are non-nucleophilic which makes it suitable for deprotonation reactions that are controlled in advanced synthesizers.

As an industrial chemical, Lithium Diisopropylamide is extensively used in organic synthesis, enolate formation, specialty intermediate manufacturing, and fine chemical production, where strict moisture control and predictable base strength are essential.

Applications of Lithium Diisopropylamide

Strong Base for Enolate Formation

Lithium Diisopropylamide is extensively used as an extremely robust and sterically inhibited base to generate enolates in organic synthesis processes used in industry. It is typically processed along with N-Butyllithium, Lithium Amide, as well as Lithium Hydride in reaction systems controlled by a controller that requires exact deprotonation.

Fine Chemical & Specialty Intermediate Manufacturing

In fine chemical production, Lithium Diisopropylamide supports carbon–carbon bond formation and selective functionalisation reactions, ensuring high reaction efficiency and reproducibility. It is often evaluated with Diisopropylamine and Tetrahydrofuran in structured synthesis environments.

Advanced Industrial Synthesis Systems

Lithium Diisopropylamide is used in industrial manufacturing that is performance-driven, especially where low-temperature and moisture-sensitive reactions are needed for consistent quality of the product.

Safety & Handling Guidelines

• Store in an air-tight, dry, and non-humid environment.
• Be sure to shield yourself from humidity and air.
• Make sure containers are tightly sealed and clearly labelled
• Avoid contact with water, as it reacts vigorously
• Keep away from heat and open flames
• Use protective gloves, goggles, face shield, and suitable industrial clothing
• Handle under strictly controlled industrial conditions
• Dispose of waste and packaging according to regulatory guidelines
  
  
  

Where to Buy Lithium Diisopropylamide?

Lithium Diisopropylamide Manufacturer

Lithium Diisopropylamide is manufactured for industrial-grade applications requiring controlled concentration, stable organolithium composition, and reliable performance in moisture-sensitive synthesis systems.

Lithium Diisopropylamide Supplier & Distributor

Lithium Diisopropylamide is supplied in bulk and industrial packaging formats for manufacturers requiring dependable quality and regulated handling. Buy Lithium Diisopropylamide from Chemicalbull Pvt. Ltd., a trusted industrial chemicals supplier and distributor in India, supporting customers with reliable sourcing and compliant logistics.

MSDS for Lithium Diisopropylamide

The MSDS for Lithium Diisopropylamide provides detailed information on the dangers and safe handling practices, the storage environment, exposure control, and emergency response protocols. Always check the MSDS prior to industrial use.

Frequently Asked Questions (FAQs)

1. What is Lithium Diisopropylamide?
   

   Lithium Diisopropylamide (LDA) is a strong, non-nucleophilic organolithium base used in advanced organic synthesis.
   
   

2. What is the chemical formula of Lithium Diisopropylamide?
   

   The chemical formula of Lithium Diisopropylamide is C₆H₁₄LiN.
   
   

3. What is the structure of Lithium Diisopropylamide?
   

   Lithium Diisopropylamide consists of a lithium cation bonded to the diisopropylamide anion, featuring a nitrogen atom attached to two isopropyl groups.
   
   

4. What is Lithium Diisopropylamide used for?
   

   Lithium Diisopropylamide is used for enolate formation, deprotonation reactions, carbon–carbon bond formation, and specialty intermediate synthesis.
   
   

5. How is Lithium Diisopropylamide synthesised?
   

   Lithium Diisopropylamide is typically synthesised by the reaction of diisopropylamine with N-Butyllithium under controlled, moisture-free industrial conditions.