N-Butyllithium | 109-72-8

Description :

Overview of N-Butyllithium

N-Butyllithium (n-BuLi) is a highly reactive organic compound extensively used as a base and nucleophile for organic syntheses. It's an essential chemical reagent used in pharmaceutical, agricultural and speciality chemical manufacturing, specifically in carbon-carbon bonding and exchange reactions between metals and halogens. N-Butyllithium typically comes as a solution within hydrocarbons and should be handled under strict conditions.

The structure of n-butyllithium is the butyl-bonded group lithium. It has an extraordinary ability to reactivate. Due to its high reactivity, this element is crucial in modern synthesis. However, it is required to follow strict safety procedures. The CAS number for n-butyllithium will ensure proper identification and regulatory compliance throughout acquisition and utilisation.

When performing multi-step chemical procedures, N-Butyllithium is frequently used in conjunction with intermediates like Monocalcium Phosphate Anhydrous, Monoethylene Glycol and Morpholine, which are available at ChemicalBull, providing complete sourcing solutions for complicated chemical synthesising workflows.

Applications of N-Butyllithium

Organic & Pharmaceutical Synthesis

• Used as a strong base for deprotonation reactions

• Enables carbon–carbon bond formation

• Essential in the synthesis of pharmaceutical intermediates and APIs

Agrochemical & Fine Chemical Manufacturing

• Used in the preparation of herbicide and pesticide intermediates

• Supports selective lithiation reactions

• Ensures high reaction efficiency and yield

Polymer & Speciality Chemicals

• An initiator for an anionic polymerisation reaction

• Utilized in speciality Elastomers as well as advanced materials

• Allows for exact control over molecular structure

Research & Advanced Laboratory Applications

• The HTML0 format is extensively utilized in research labs for studies of the reaction mechanism

• Essential reagent in organometallic chemistry

• Sometimes, these solvents are combined with Monoethylene Glycol and other intermediates, such as Morpholine when planning synthesis

Safety & Handling Guidelines

• It is also pyrophoric. use only in an atmosphere of inertity

• Use a laboratory coat and gloves and a face shield, eye shield and wear eye protection

• Do not come into contact with moisture, air and solvents that are protic.

• Store in approved containers under inert gas

• Follow strictly MSDS and the most advanced safety protocols

Where to Buy N-Butyllithium?

N-Butyllithium Manufacturer

ChemicalBull supplies high-quality N-Butyllithium for pharmaceutical, agrochemical, and speciality chemical synthesis, meeting controlled supply standards.

N-Butyllithium Supplier & Distributor

• Supplied in controlled concentrations and packaging

• Export-grade material with COA, TDS & MSDS

• Reliable supply for manufacturers and R&D facilities

• Explore related products: Monocalcium Phosphate Anhydrous, Monoethylene Glycol, Morpholine

N-Butyllithium MSDS

The Material Safety Data Sheet (MSDS) provides critical information on handling, storage, reactivity hazards, fire risks, and emergency response procedures. Always review the MSDS before use in any laboratory or industrial environment.

Frequently Asked Questions (FAQs)

1. What is N-Butyllithium used for?

   It is used as a strong base and nucleophile in organic synthesis, especially for lithiation and carbon–carbon bond formation reactions.
   
   
   

2. What is the N-Butyllithium CAS number?

   The n-butyllithium CAS no is 109-72-5.
   
   
   

3. Is N-Butyllithium dangerous to handle?

   Yes. It is highly reactive and pyrophoric, and must be handled only by trained professionals under inert conditions following strict safety guidelines.