Lenalidomide | 191732-72-6

Cas No :

191732-72-6

Quality Standards :

Ih

Form :

Powder

Molecular Weight :

259.26 G/Mol

Molecular Formula :

C13H13N3O3

Melting Point :

265 - 268 °C

Description :

Overview of Lenalidomide

 

Lenalidomide is an immunomodulatory drug (IMiD) used for treating multiple myeloma, myelodysplastic syndromes, and certain lymphomas. Known for its potent anti-cancer, anti-angiogenic, and immunomodulatory properties, Lenalidomide is widely used in hematological oncology.

This API appears as a white to off-white crystalline powder with controlled stability requirements.

Its mechanism—modulation of the cereblon protein and enhancement of immune response—leads to tumor cell death, inhibition of angiogenesis, and stimulation of T-cell- and NK-cell-mediated immunity.

Related products include Thalidomide, Pomalidomide, Bortezomib, and other immunomodulatory and anticancer agents used to treat hematological malignancies.

 

 

Applications of Lenalidomide

 

Pharmaceutical API

 

  • Used in anti-cancer medications for hematological malignancies
  • Effective in treating multiple myeloma, myelodysplastic syndromes (MDS), and mantle cell lymphoma
  • It modulates the immune system and induces cancer cell apoptosis
  • Inhibits angiogenesis and tumor growth

 

Formulation Development

 

  • Used in hard gelatin capsules
  • Requires a moisture-controlled manufacturing environment
  • Offers good stability under controlled storage conditions
  • Available in multiple strength formulations

 

Oncological Treatment

 

  • Improves progression-free survival in multiple myeloma
  • Effective in patients with deletion 5q myelodysplastic syndrome
  • Used in combination with chemotherapy regimens
  • Demonstrates a better safety profile than thalidomide

 

 

Safety & Handling Guidelines

 

  • Highly potent—use appropriate containment measures
  • Avoid inhalation of powder and skin contact
  • Use PPE, including gloves, goggles, and protective clothing
  • Teratogenic—handle with extreme caution following strict protocols
  • Store in a cool, dry place with controlled access
  • Follow COA and MSDS instructions strictly

 

 

Where to Buy Lenalidomide?

 

Lenalidomide Manufacturer

 

ChemicalBull supplies high-purity Lenalidomide API, meeting IP/EP/USP quality standards for pharmaceutical formulations.

 

Lenalidomide Supplier & Distributor

 

  • Available in bulk packing for formulation units with appropriate containment
  • Stable and high-purity grade for research and production
  • COA, MSDS, and regulatory documents provided

 

 

MSDS

 

Includes detailed safety instructions, hazard identification, and storage guidelines.

 

 

Frequently Asked Questions (FAQs)

 

  1. What is Lenalidomide used for?

    It is used for treating multiple myeloma, myelodysplastic syndromes, and certain types of lymphoma.

  2. Is Lenalidomide related to Thalidomide?

    Yes, Lenalidomide is a derivative of Thalidomide with improved efficacy and safety profile, but still carries teratogenic risks.

  3. Is Lenalidomide stable for capsule formulation?

    Yes, under controlled moisture and temperature conditions, it is stable in capsule formulations.