Lenalidomide | 191732-72-6
Cas No :
191732-72-6
Quality Standards :
Ih
Form :
Powder
Molecular Weight :
259.26 G/Mol
Molecular Formula :
C13H13N3O3
Melting Point :
265 - 268 °C
Description :
Overview of Lenalidomide
Lenalidomide is an immunomodulatory drug (IMiD) used for treating multiple myeloma, myelodysplastic syndromes, and certain lymphomas. Known for its potent anti-cancer, anti-angiogenic, and immunomodulatory properties, Lenalidomide is widely used in hematological oncology.
This API appears as a white to off-white crystalline powder with controlled stability requirements.
Its mechanism—modulation of the cereblon protein and enhancement of immune response—leads to tumor cell death, inhibition of angiogenesis, and stimulation of T-cell- and NK-cell-mediated immunity.
Related products include Thalidomide, Pomalidomide, Bortezomib, and other immunomodulatory and anticancer agents used to treat hematological malignancies.
Applications of Lenalidomide
Pharmaceutical API
- Used in anti-cancer medications for hematological malignancies
- Effective in treating multiple myeloma, myelodysplastic syndromes (MDS), and mantle cell lymphoma
- It modulates the immune system and induces cancer cell apoptosis
- Inhibits angiogenesis and tumor growth
Formulation Development
- Used in hard gelatin capsules
- Requires a moisture-controlled manufacturing environment
- Offers good stability under controlled storage conditions
- Available in multiple strength formulations
Oncological Treatment
- Improves progression-free survival in multiple myeloma
- Effective in patients with deletion 5q myelodysplastic syndrome
- Used in combination with chemotherapy regimens
- Demonstrates a better safety profile than thalidomide
Safety & Handling Guidelines
- Highly potent—use appropriate containment measures
- Avoid inhalation of powder and skin contact
- Use PPE, including gloves, goggles, and protective clothing
- Teratogenic—handle with extreme caution following strict protocols
- Store in a cool, dry place with controlled access
- Follow COA and MSDS instructions strictly
Where to Buy Lenalidomide?
Lenalidomide Manufacturer
ChemicalBull supplies high-purity Lenalidomide API, meeting IP/EP/USP quality standards for pharmaceutical formulations.
Lenalidomide Supplier & Distributor
- Available in bulk packing for formulation units with appropriate containment
- Stable and high-purity grade for research and production
- COA, MSDS, and regulatory documents provided
MSDS
Includes detailed safety instructions, hazard identification, and storage guidelines.
Frequently Asked Questions (FAQs)
-
What is Lenalidomide used for?
It is used for treating multiple myeloma, myelodysplastic syndromes, and certain types of lymphoma. -
Is Lenalidomide related to Thalidomide?
Yes, Lenalidomide is a derivative of Thalidomide with improved efficacy and safety profile, but still carries teratogenic risks. -
Is Lenalidomide stable for capsule formulation?
Yes, under controlled moisture and temperature conditions, it is stable in capsule formulations.