L-Histidine | 71-00-1

Description :

Overview of L-Histidine

L-Histidine is a high-quality pharmaceutical grade essential amino acid that is widely employed in medical, pharmaceutical nutritional and biochemical formulations. It plays an essential part in protein synthesis, enzyme activity, as well as metabolism, specifically as a precursor to bioactive substances.

In the pharmaceutical industry, L-Histidine is valued for its defined chemical structure, buffering properties, and compatibility with regulated formulations. It is manufactured under controlled conditions to meet pharmacopeial standards for purity, stability, and batch consistency.

As a pharma chemical, L-Histidine is used in clinical nutrition, metabolic support, and specialised therapeutic formulations.

Applications of L-Histidine

Pharmaceutical & Clinical Nutrition Use

L-Histidine is used in pharmaceutical and clinical nutrition formulations to support protein synthesis, immune function, and metabolic balance. It is commonly included in enteral and parenteral nutrition products where essential amino acid supplementation is required.

In amino-acid-based formulations, it is often evaluated alongside L-Arginine for balanced nitrogen metabolism and physiological support.

Pharmaceutical Chemistry & Structural Characteristics

From the perspective of pharmaceutical chemistry from a chemistry perspective, the L-histidine structure is comprised of an imidazole-like side chain that contributes to its buffering capabilities and participation in active enzyme sites. This unique structure allows involvement in the regulation of acid bases and metal Ion binding.

L-Histidine also serves as a biochemical precursor to histamine and is a structural component in dipeptides such as L-Carnosine, making it important in antioxidant and tissue-protective formulations.

Therapeutic & Specialty Formulations

L-Histidine is used in specialised pharmaceutical and nutritional formulations designed for metabolic support, haemoglobin synthesis, and cellular function. It is frequently formulated with amino acids such as L-Glutamine in regulated clinical nutrition and recovery-support products.

Safety & Handling Guidelines

• Keep it in a cool, dry, well-ventilated, and dry area
• Seal containers well and keep them clearly labeled
• Be sure to protect yourself from the elements
• Avoid inhalation of dust during handling
• Avoid direct contact with the eyes and prolonged skin exposure
• Use appropriate PPE, including gloves and eye protection
• Handle under controlled pharmaceutical manufacturing conditions
• Dispose of waste according to regulatory guidelines
  
  
  

Where to Buy L-Histidine?

L-Histidine Manufacturer

L-Histidine is manufactured for pharmaceutical and clinical nutrition applications where high purity, controlled amino acid composition, and regulatory compliance are essential.

L-Histidine Supplier & Distributor

L-Histidine is supplied in pharmaceutical-grade packaging suitable for formulation manufacturers and healthcare producers. As a pharmaceutical chemicals supplier and distributor, Chemicalbull Pvt. Ltd. supports customers with reliable sourcing and standard regulatory documentation.

MSDS for L-Histidine

The MSDS for L-Histidine provides detailed information on chemical hazards, safe handling practices, storage requirements, exposure controls, and emergency procedures. Always review the MSDS before pharmaceutical manufacturing use.

Frequently Asked Questions (FAQs)

1. What is L-Histidine used for?
   

   L-Histidine is used in pharmaceutical and clinical nutrition formulations to support protein synthesis, metabolic balance, and immune function.
   
   

2. What is the structure of L-Histidine?
   

   L-Histidine structure includes an amino acid backbone with an imidazole-containing side chain, which contributes to its buffering and biochemical activity.
   
   

3. Is L-Histidine an essential amino acid?
   

   Yes, L-Histidine is considered an essential amino acid, particularly important in growth, tissue repair, and clinical nutrition.
   
   

4. Is L-Histidine suitable for pharmaceutical manufacturing?
   

   Yes, pharmaceutical-grade L-Histidine is widely used in regulated healthcare, nutritional, and specialty formulation products.
   
   

5. Is L-Histidine chemically stable?
   

   L-Histidine exhibits good chemical stability when stored and handled under recommended pharmaceutical conditions.