Iodotrimethylsilane (Trimethylsilyl Iodide) | 16029-98-4

Cas No :

16029-98-4

Synonyms :

Form :

Liquid

Molecular Weight :

200.09 G/Mol

Molecular Formula :

C3H9ISI

Boiling Point :

106 °C

Flash Point :

-31 °C

Solubility :

Chloroform

Description :

Overview of Iodotrimethylsilane (Trimethylsilyl Iodide)

 

Iodotrimethylsilane (CAS: 16029-98-4), commonly known as Trimethylsilyl Iodide (TMSI), is a colorless to pale yellow liquid widely used in organic synthesis. It is also known by synonyms such as TMS Iodide, Trimethylsilyl Monoiodide, and Iodo(trimethyl)silane.

This compound is a highly reactive silylating and iodinating reagent, making it very useful in chemical reactions involving cleavage, protection, and transformation of functional groups. It is especially effective in breaking ethers, esters, and other oxygen-containing compounds.

It is part of the Industrial Chemicals category and is widely used in pharmaceutical and chemical industries.

At ChemicalBull, we supply high-quality Trimethylsilyl Iodide suitable for industrial and laboratory applications.

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Tetrachloro-1,4-Benzoquinone

 

Applications of Iodotrimethylsilane (Trimethylsilyl Iodide)

 

Organic Synthesis

 

Iodotrimethylsilane is widely used as a reagent in organic chemistry.

  • Used for cleavage of ethers and esters
  • Helps introduce iodine into organic molecules
  • Used in preparation of complex intermediates

 

Pharmaceutical Industry

 

This compound plays an important role in drug manufacturing.

  • Used in pharmaceutical intermediates
  • Helps in synthesis of active drug molecules
  • Useful in selective chemical reactions

 

Silylation & Protection Reactions

 

Trimethylsilyl Iodide is commonly used for protection reactions.

  • Protects alcohols and acids
  • Improves reaction selectivity
  • Used in multi-step synthesis

 

Chemical & Research Applications

 

  • Used in laboratory research
  • Important for advanced chemical reactions
  • Helps in studying reaction mechanisms

 

Safety & Handling Guidelines

 

  • Use gloves, goggles, and protective clothing
  • Handle in a well-ventilated area
  • Avoid contact with moisture
  • Store in tightly closed containers
  • Keep away from water and strong oxidizers

 

Iodotrimethylsilane (Trimethylsilyl Iodide) MSDS

 

  • May cause irritation to skin, eyes, and respiratory system
  • Reacts with moisture and releases fumes
  • Follow proper safety measures
  • Refer to MSDS for detailed handling instructions

 

Where to Buy Iodotrimethylsilane (Trimethylsilyl Iodide)?

 

Iodotrimethylsilane Manufacturer

 

ChemicalBull is a reliable manufacturer of high-quality Trimethylsilyl Iodide for industrial use.

 

Iodotrimethylsilane Supplier & Distributor

 

  • Available in bulk and small quantities
  • Suitable for industrial and lab use
  • COA, MSDS, and technical documents available
  • Fast and reliable supply

 

Frequently Asked Questions (FAQs)

 

  1. What is the molecular formula of Iodotrimethylsilane?

    Molecular Formula: C₃H₉ISi

  2. What are the synonyms of Trimethylsilyl Iodide?


    It is also known as TMSI, TMS Iodide, Trimethylsilyl Monoiodide, and Iodo(trimethyl)silane.

  3. What is Iodotrimethylsilane used for?


    It is used in organic synthesis, pharmaceutical intermediates, silylation reactions, and research applications.