Indomethacin | 53-86-1
Cas No :
53-86-1
Form :
Powder
Molecular Weight :
357.79 G/Mol
Molecular Formula :
C19H16CLNO4
Melting Point :
155 °C
Solubility :
Chloroform, Methanol
Description :
Overview of Indomethacin
Indomethacin is a potent nonsteroidal anti-inflammatory drug (NSAID) widely used in the pharmaceutical industry for the treatment of pain, inflammation, and fever. It inhibits cyclooxygenase (COX) enzymes, reducing the synthesis of prostaglandins responsible for inflammation and pain. Indomethacin is formulated in oral capsules, tablets, and topical gels, providing effective relief in conditions like arthritis, gout, and musculoskeletal disorders.
Indomethacin is the standard globally recognized name for this compound and is commonly referenced in pharmacopeia guidelines, pharmaceutical regulatory documents, clinical formulations, and safety data sheets.
Applications of Indomethacin
Pharmaceutical Formulations
Used in tablets, capsules, and gels for pain relief, anti-inflammatory therapy, and fever management. Often combined with gastroprotective agents like Omeprazole or Misoprostol in combination therapies.
Rheumatology & Arthritis Therapy
Indomethacin effectively reduces joint inflammation, pain, and stiffness in conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
Gout & Musculoskeletal Disorders
Applied in the management of acute gout attacks, tendonitis, and bursitis to relieve pain and swelling.
Research & Development
Used in pharmaceutical R&D for developing novel NSAID formulations, topical delivery systems, and combination therapies for inflammatory disorders.
Safety & Handling Guidelines
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Store in a cool, dry, well-ventilated place
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Keep containers tightly sealed to prevent contamination
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Avoid inhalation of powder; use gloves, goggles, and PPE
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Handle according to GMP and MSDS guidelines
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Refer to the MSDS for complete safety, first-aid, and disposal instructions
Where to Buy Indomethacin?
Indomethacin Manufacturer
High-purity Indomethacin is manufactured under controlled pharmaceutical standards ensuring stability, efficacy, and regulatory compliance.
Indomethacin Supplier & Distributor
ChemicalBull supplies pharma-grade Indomethacin in bulk packaging suitable for pharmaceutical manufacturers, research labs, and global distributors. Contact us today to request samples or place bulk orders.
MSDS for Indomethacin
The MSDS provides full information on chemical properties, handling precautions, toxicology, exposure control, and emergency measures for safe pharmaceutical use.
Frequently Asked Questions (FAQs)
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What is Indomethacin used for?
It is used to treat pain, inflammation, arthritis, gout, and other musculoskeletal disorders. -
Can Indomethacin be combined with gastroprotective agents?
Yes, it is often combined with Omeprazole or Misoprostol to reduce gastrointestinal side effects. -
Is Indomethacin safe for oral and topical use?
Yes, pharma-grade Indomethacin is formulated for oral tablets, capsules, and topical gels under controlled conditions. -
How is Indomethacin supplied?
ChemicalBull supplies high-purity Indomethacin in bulk containers with COA, MSDS, and full regulatory documentation. -
What forms of Indomethacin are available?
It is supplied for tablets, capsules, and topical gels for pharmaceutical manufacturing.