What is Econazole Nitrate's structure?

Econazole Nitrate is an imidazole derivative with molecular formula C₁₈H₁₅Cl₃N₂O·HNO₃, containing a triple-chlorinated phenyl group and an imidazole ring.

What is Econazole Nitrate cream used for?

It is used for treating fungal skin infections, including athlete's foot, jock itch, ringworm, and yeast infections of the skin.

Is Econazole Nitrate the same as Clotrimazole?

No, while both are imidazole antifungals with similar mechanisms, they are different compounds with some variations in spectrum and potency.

Watch Video MSDS Specifications

Econazole Nitrate | 24169-02-06

Cas No :

24169-02-06

Form :

Solid

Molecular Weight :

444.7 G/Mol

Molecular Formula :

C₁₈H₁₅CL₃N₂O.HNO₃

Solubility :

Methanol

Description :

Overview of Econazole Nitrate

Econazole Nitrate is an imidazole-based antifungal with a wide spectrum that is used to treat superficial fungal diseases like dermatophytosis, candidiasis, and tinea infections. The drug is known for its antifungal action and its broad coverage. Econazole Nitrate is widely utilised in dermatological formulations that are used for the treatment of mycosis on the skin.

This API appears as a white to slightly yellowish crystalline powder with good stability under controlled storage conditions. Its mechanism—inhibition of fungal cytochrome P450-dependent 14α-lanosterol demethylase—disrupts ergosterol synthesis in fungal cell membranes, leading to cell death.

Related products include Imidazole, Clotrimazole, Miconazole, Ketoconazole, and other azole antifungal agents used in topical and systemic antifungal therapy.

Applications of Econazole Nitrate

Pharmaceutical API

Used in topical antifungal medications
Effective against dermatophytes, yeasts, and moulds
Treats tinea pedis, tinea cruris, tinea corporis, and cutaneous candidiasis
Shows activity against some gram-positive bacteria

Formulation Development

Used in creams, ointments, lotions, and powders
Available in vaginal suppositories for vulvovaginal candidiasis
Offers good skin penetration and local retention
Stable in various topical formulation bases

Dermatological Treatment

Provides rapid relief from fungal skin infections
Reduces itching, inflammation, and skin lesions
Once or twice daily application regimen
Suitable for various anatomical sites

Safety & Handling Guidelines

Avoid inhalation of fine powder
Use gloves, goggles, and protective clothing during handling
Store in a cool, dry place away from light and moisture
Follow COA and MSDS instructions strictly

Where to Buy Econazole Nitrate?

Econazole Nitrate Manufacturer

ChemicalBull supplies high-purity Econazole Nitrate API, meeting IP/EP/USP quality standards for pharmaceutical formulations.

Econazole Nitrate Supplier & Distributor

Available in bulk packing for formulation units
Stable and high-purity grade for research and production
COA, MSDS, and regulatory documents provided

MSDS

Includes detailed safety instructions, hazard identification, and storage guidelines.

Frequently Asked Questions (FAQs)

What is Econazole Nitrate's structure?
Econazole Nitrate is an imidazole derivative with molecular formula C₁₈H₁₅Cl₃N₂O·HNO₃, containing a triple-chlorinated phenyl group and an imidazole ring.
What is Econazole Nitrate cream used for?
It is used for treating fungal skin infections, including athlete's foot, jock itch, ringworm, and yeast infections of the skin.
Is Econazole Nitrate the same as Clotrimazole?
No, while both are imidazole antifungals with similar mechanisms, they are different compounds with some variations in spectrum and potency.