Cyclohexylamine | 108-91-8

Description :

Overview of Cyclohexylamine

Cyclohexylamine can be described as a pharmaceutical grade Alicyclic amine that is widely utilized as a chemical intermediary in the synthesis of pharmaceuticals. It is a colorless to pale liquid, with an odour that is characteristic of amines and a strong basicity because of the presence of an amine primary group.

In pharmaceutical manufacturing, Cyclohexylamine is valued for its reactivity, structural stability, and role as a building block in the synthesis of active pharmaceutical ingredients and intermediates. It is produced under controlled conditions to meet quality, purity, and documentation requirements.

As a pharma chemical, Cyclohexylamine is primarily used in API synthesis, salt formation, and specialty chemical processing.

Applications of Cyclohexylamine

Pharmaceutical Intermediate & Synthesis Use

Cyclohexylamine is used as an intermediate in the synthesis of pharmaceutical actives, salts, and specialty intermediates. Its alicyclic amine structure allows participation in amide formation, alkylation, and condensation reactions.

In synthetic route development, it is often evaluated alongside Piperidine for amine-based structural modification.

Pharmaceutical Chemistry & Structural Characteristics

From a pharmaceutical chemistry perspective, the cyclohexylamine structure consists of a saturated six-membered cyclohexane ring attached to a primary amine group. This structure provides steric bulk and controlled basicity, making it suitable for selective chemical reactions.

Its chemical behaviour differs significantly from aromatic amines, supporting its use in diverse synthetic pathways.

Industrial & Regulated Manufacturing Use

Cyclohexylamine is manufactured as a high-purity pharmaceutical raw material with strict control over water content, impurities, and assay value. It is suitable for regulated pharmaceutical synthesis environments and large-scale intermediate production.

In amine-based chemical processes, it may be referenced alongside Diethylamine and coupling agents such as N,N-Dicyclohexylcarbodiimide for reaction optimisation.

Safety & Handling Guidelines

• Store in a cool, dry, and well-ventilated area
• Keep containers tightly sealed and clearly labelled
• Avoid inhalation of vapours
• Avoid direct contact with skin and eyes
• Use appropriate personal protective equipment
• Handle under controlled chemical processing conditions
• Dispose of waste according to regulatory guidelines
  
  
  

Where to Buy Cyclohexylamine?

Cyclohexylamine Manufacturer

Cyclohexylamine is a chemical used in specialty and pharmaceutical chemical applications in which controlled synthesis, consistent quality, and compliance with regulatory requirements are necessary.

Cyclohexylamine Supplier & Distributor

Pharmaceutical-grade Cyclohexylamine is supplied in suitable packaging for API and intermediate manufacturers. As a pharmaceutical chemicals supplier and distributor, Chemicalbull Pvt. Ltd. supports reliable sourcing with standard documentation.

MSDS for Cyclohexylamine

The MSDS for Cyclohexylamine provides information on chemical hazards, safe handling practices, storage conditions, exposure controls, and emergency response measures. It should be reviewed before pharmaceutical or chemical processing use.

Frequently Asked Questions (FAQs)

1. What is Cyclohexylamine used for?
   

   Cyclohexylamine is used as a chemical intermediate in pharmaceutical synthesis, salt formation, and specialty chemical manufacturing.
   
   

2. What are the hazards of Cyclohexylamine?
   

   Cyclohexylamine may cause irritation to skin, eyes, and respiratory tract and should be handled with appropriate safety precautions.
   
   

3. What is the structure of Cyclohexylamine?
   

   Cyclohexylamine structure consists of a cyclohexane ring bonded to a primary amine group.
   
   

4. What is the IUPAC name of Cyclohexylamine?
   

   The cyclohexylamine IUPAC name is cyclohexan-1-amine.
   
   

5. What is the difference between Cyclohexylamine and Aniline?
   

   Cyclohexylamine is an alicyclic amine, while aniline is an aromatic amine; this difference affects their reactivity and chemical behaviour.