Chlorhexidine Gluconate | 18472-51-0
Cas No :
18472-51-0
Form :
Powder
Molecular Weight :
897.8 G/Mol
Molecular Formula :
C34H54CL2N10O14
Boiling Point :
360 °C
Melting Point :
195 °C
Flash Point :
190 °C
Solubility :
Soluble In Water; Soluble In Ethanol; Insoluble In Ether
Description :
Overview of Chlorhexidine Gluconate
Chlorhexidine Gluconate can be described as a pharmaceutical-grade biguanide cationic compound that is widely utilized for the broad spectrum of antimicrobial capabilities it has. It is offered in the form of an aqueous solution chlorhexidine and gluconic acid that has improved solubility and stability in formulations.
In pharmaceutical manufacturing, Chlorhexidine Gluconate is valued for its strong antimicrobial efficacy, chemical stability, and compatibility with topical, oral, and medical antiseptic formulations. Chlorhexidine Gluconate manufacturers in India produce this compound under GMP conditions to meet pharmacopeial and regulatory standards.
As a pharma chemical, Chlorhexidine Gluconate is used extensively in antiseptic, disinfectant, and infection-control products.
Applications of Chlorhexidine Gluconate
Pharmaceutical API & Antiseptic Formulations
Chlorhexidine Gluconate is used as an active pharmaceutical ingredient in topical antiseptics, oral care products, and medical disinfectants. Its cationic nature allows strong binding to microbial cell membranes, resulting in sustained antimicrobial action.
In antiseptic formulation development, it is often evaluated alongside Povidone Iodine for comparative antimicrobial performance.
Pharmaceutical Chemistry & Functional Characteristics
From a chemistry standpoint, for pharmaceuticals, Chlorhexidine Gluconate consists of chlorhexidine molecules that are stabilized by gluconate counter-ions. This salt enhances the solubility of aqueous solutions and formulation compatibility while also maintaining the antimicrobial properties.
Its chemical properties support use in solutions, gels, sprays, and impregnated medical materials.
Industrial & Regulated Manufacturing Use
Chlorhexidine Gluconate is produced as a pharmaceutical raw material that has strict control of the assay value, microbial limit, and the impurity characteristics. It is ideal for large-scale pharmaceutical and health production of products.
In infection-control formulation studies, it may be referenced alongside agents such as Benzalkonium Chloride and Hydrogen Peroxide for formulation optimisation.
Safety & Handling Guidelines
- Store in a cool, dry, and controlled environment
- Protect from light and contamination
- Keep containers tightly sealed and clearly labelled
- Avoid inhalation of mist or vapours
- Avoid direct contact with the eyes
- Use appropriate personal protective equipment
- Handle under controlled pharmaceutical manufacturing conditions
- Dispose of waste according to regulatory guidelines
Where to Buy Chlorhexidine Gluconate?
Chlorhexidine Gluconate Manufacturer
Chlorhexidine Gluconate is manufactured for pharmaceutical applications where controlled composition, consistent antimicrobial activity, and regulatory compliance are required.
Chlorhexidine Gluconate Supplier & Distributor
Pharmaceutical-grade Chlorhexidine Gluconate is available in a suitable packaging for formulation producers. As a supplier of pharmaceutical chemicals and distributor, Chemicalbull Pvt. Ltd. provides the reliability of sourcing by providing standard documentation.
MSDS for Chlorhexidine Gluconate
The MSDS for Chlorhexidine Gluconate contains information about chemicals, handling safety precautions, storage conditions safety measures, and exposure control measures. It is recommended to review it prior to the use of pharmaceuticals in manufacturing.
Frequently Asked Questions (FAQs)
-
What is the use of Chlorhexidine Gluconate?
Chlorhexidine Gluconate is used in pharmaceutical and healthcare formulations as an antimicrobial and antiseptic agent. -
What is the difference between Chlorhexidine Digluconate and Chlorhexidine Gluconate?
Both terms refer to the same compound; “digluconate” emphasises the presence of two gluconate ions associated with the chlorhexidine molecule. -
Is Chlorhexidine Gluconate an API or excipient?
Chlorhexidine Gluconate functions as an active pharmaceutical ingredient due to its antimicrobial activity.