Cetyltrimethylammonium Bromide | 57-09-0
Cas No :
57-09-0
Synonyms :
Form :
Solid
Molecular Weight :
364.45 G/Mol
Molecular Formula :
C19H42BRN
Melting Point :
248–251 °C
Flash Point :
244 °C
Solubility :
Soluble In Water; Forms Clear Solution; Heating To 30–35 °C May Be Required
Description :
Overview of Cetyltrimethylammonium Bromide
Cetyltrimethylammonium Bromide, commonly abbreviated as CTAB, is a powerful quaternary ammonium-based cationic surfactant with a Molecular Weight of 364.45 g/mol and a Melting Point of 237–243°C. As a leading Pharmaceutical Intermediate Supplier, Chemical Bull provides high-purity CTAB in white crystalline powder form.
Identified by CAS 57-09-0, this compound is highly valued for its ability to interact with negatively charged molecules, such as DNA and proteins, making it indispensable in molecular biology and advanced cosmetic science.
Applications of Cetyltrimethylammonium Bromide
Biotechnology & Molecular Biology (DNA Extraction)
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Cell Lysis: It effectively disrupts cell membranes and precipitates polysaccharides, which are common contaminants in plant tissue.
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DNA Purification: It forms a complex with DNA in high-salt conditions, allowing for the isolation of high-purity genetic material.
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Synergistic Use: Often used in buffer solutions alongside pH regulators like Lactic Acid or specialized chelating agents.
Personal Care & Hair Care
In the Personal Care Chemicals sector, it acts as a high-performance conditioner:
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Antistatic Agent: Because it is cationic (positively charged), it neutralizes the negative charge on hair strands, reducing frizz and improving manageability.
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Emulsifier: Helps stabilize oil-in-water emulsions in luxury creams and lotions. It pairs exceptionally well with fatty acids like Lauric Acid to create balanced surfactant systems.
Healthcare & Antiseptics
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Topical Antiseptic: Used as an active ingredient in antiseptic creams and liquids due to its potent antimicrobial activity against bacteria and fungi.
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Nanoparticle Synthesis: Acts as a stabilizing agent or "template" in the manufacture of gold nanorods and other specialized nanomaterials.
Where to Buy Cetyltrimethylammonium Bromide?
Cetyltrimethylammonium Bromide (CTAB) Manufacture
High-Scale Manufacture Chemical Bull facilitates the CTAB manufacture process through the alkylation of trimethylamine with cetyl bromide. Our production partners ensure a high-assay crystalline product with strictly controlled moisture and heavy metal limits, meeting the rigorous demands of laboratory and pharmaceutical grades.
Cetyltrimethylammonium Bromide Supplier and Distributor
Reliable Supplier & Distributor As a global supplier and distributor, we provide CTAB to research institutions, biotech firms, and cosmetic manufacturers. We offer specialized packaging, such as 25kg fiber drums with inner PE lining, to maintain the product's dry, free-flowing state and prevent clumping during transit.
Cetyltrimethylammonium Bromide MSDS
Compliance CTAB is classified as hazardous and can cause skin irritation or respiratory distress if mishandled. Every batch is supplied with an updated MSDS (Material Safety Data Sheet) and a COA (Certificate of Analysis). These documents provide essential data on eco-toxicity, handling precautions, and the necessary PPE (Personal Protective Equipment) for safe industrial use.
Safety, Handling & Professional Storage
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Handling: Highly irritating to eyes and skin. It is also toxic to aquatic life. Always use gloves, safety goggles, and a dust mask when handling the powder form.
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Storage: Store in a cool, dry, and well-ventilated area. Keep the container tightly closed, as CTAB is sensitive to moisture and can lose its crystalline integrity if exposed to high humidity.
Frequently Asked Questions (FAQs)
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What is the main difference between CTAB and CTAC?
CTAB uses a Bromide ion, whereas CTAC (Cetrimonium Chloride) uses a Chloride ion. CTAB is generally preferred in DNA extraction protocols due to its specific precipitation characteristics. -
Is CTAB soluble in water?
Yes, CTAB is soluble in water, especially when heated. Its solubility increases significantly as the temperature rises above its Krafft point. -
Can CTAB be used in sulfate-free formulations?
Absolutely. As a cationic surfactant, it is a key component in "clean beauty" conditioners and treatments that avoid traditional sulfates.