Canagliflozin Hemihydrate | 928672-86-0

Description :

Overview of Canagliflozin Hemihydrate

Canagliflozin Hemihydrate is a pharmaceutical-grade SGLT2 inhibitor intermediate used in the formulation of antidiabetic medications. It is produced through a multistep organic synthesis that involves selective functional group protection, coupling reactions, and controlled crystallization to yield the hemihydrate form required for stability and bioavailability. The compound is designed to support the development of APIs for the management of Type 2 Diabetes.

Known for its role in promoting renal glucose excretion, Canagliflozin Hemihydrate is widely used in pharmaceutical manufacturing for oral solid dosage forms. It is recognized in technical documentation and pharmacopeia references related to diabetes care formulations.

Applications of Canagliflozin Hemihydrate

Pharmaceutical API Manufacturing

Used as a key intermediate in the production of Canagliflozin-based antidiabetic drugs. It supports the synthesis of SGLT2 inhibitors and is compatible with ingredients like Metformin, Dapagliflozin, and Empagliflozin in combination formulations.

Diabetes Care Formulations

Applied in developing tablets and extended-release dosage forms for Type 2 Diabetes management.

Research & Development

Used in medicinal chemistry research and clinical development for improving oral antidiabetic drug profiles.

Custom Synthesis & CRO Support

Employed by chemical R&D facilities for structural modifications, analog development, and formulation trials.

Safety & Handling Guidelines

• Store in an airtight, dry container away from light

• Avoid inhalation of fine powder; use proper PPE

• Keep away from high moisture and extreme temperatures

• Handle with gloves, mask, and laboratory protection

• Always follow MSDS guidelines for disposal and emergency response

Where to Buy Canagliflozin Hemihydrate?

Canagliflozin Hemihydrate Manufacturer

Produced under high-purity, controlled synthesis suitable for pharmaceutical API development.

Canagliflozin Hemihydrate Supplier & Distributor

ChemicalBull supplies pharma-grade Canagliflozin Hemihydrate in secure packaging with COA, MSDS, and global export support.

MSDS for Canagliflozin Hemihydrate

MSDS provides safety hazards, exposure guidelines, safe handling, and first-aid information.

Frequently Asked Questions (FAQs)

1. What is Canagliflozin Hemihydrate used for?

   It is used to manufacture antidiabetic medications based on SGLT2 inhibition for Type 2 Diabetes treatment.
   
   

2. Is Canagliflozin Hemihydrate stable?

   Yes, the hemihydrate form provides good stability when stored properly in a sealed, dry environment.
   
   

3. Which industry uses Canagliflozin Hemihydrate?

   Primarily the pharmaceutical industry for API manufacturing and R&D applications.